A hydrogenation method for preparing HBPA includes placing a BPA reaction liquid into a hydrogenation vessel with a hollow-shaft stirrer installed inside; starting the hollow-shaft stirrer to stir the BPA reaction liquid and simultaneously allowing hydrogen gas evenly distributed over and contact well with the BPA reaction liquid; in the presence of a single-metallic Ru/Al2O3 hydrogenation catalyst to proceed with a catalytic hydrogenation at low temperature and low pressure to produce HBPA, the HBPA has a yield of 99.7% or more, and particularly having a trans/trans isomer ratio above 63%.

A reactor system for high throughput applications includes a plurality of reactor assemblies, each reactor assembly including: a fluid source, which fluid source is adapted to provide a pressurized fluid to the flow-through reactors, a flow splitter which flow splitter includes a planar microfluidic chip, which microfluidic chip has a chip inlet channel and a plurality of chip outlet channels, which microfluidic chip further includes a plurality of flow restrictor channels, where each flow restrictor channel extends from said chip inlet channel to an associated chip outlet channel, where the chip inlet channel and the chip outlet channels each have a diameter, where the diameter of the chip inlet channel is the same or less than the length of said chip inlet channel and where the diameter of each chip outlet channel is the same or less than the length of said chip outlet channel.

A method of separating a plurality of particles (14) from a portion of fluid, comprising directing the plurality of particles (14) into a microchannel (12). A first portion (16) of particles (14) is focused into an equilibrium position in the microchannel (12). The focused first portion (16) is directed into a first outlet (18) aligned with the equilibrium position. A portion of the fluid is directed into one or more outlets (20, 22). A microfluidic device (10) for separating a plurality of particles (14) from a portion of fluid, comprising a microchannel (12) having a first aspect ratio and a length L, thereby focusing the particles (14) directed therein into an equilibrium position in the microchannel, wherein at least a first portion (16) of the particles (14) focuses at distance X from a beginning of the microchannel (12). A first outlet (18) disposed after distance X and aligned with the equilibrium position to receive at least the first portion (16) of the particles (14) after the first portion (16) focuses into an equilibrium position in the microchannel (12). At least a second outlet (20) for receiving a second portion of the particles (14) before the second portion focuses into an equilibrium position.

Modular reactors comprising a chassis, reactor tubing and optionally a cover are disclosed. The chassis comprises a plurality of channels of different lengths into which a length of reactor tubing is placed to create the reactor portion of the flow reactor.

A method comprises enabling epoxy vegetable oil to react with a compound of a formula III in a second microstructured reactor to obtain the vegetable oil polyol. Compared with the existing technology, the present invention adopts a novel, environment-friendly ring-opening agent, the obtained polyol is novel in structure, high in hydroxyl value, even in distribution and low in viscosity, and can completely replace traditional petrochemical polyol to be applied to the preparation of polyurethane foam materials.

A polyurethane polyol, and a preparation method and application thereof. The method comprises the following steps: (1) carrying out a reaction on phosphorus oxychloride, epichlorohydrin, a first acidic catalyst and an inert solvent in a first microchannel reactor to obtain a chloroalkoxy phosphorus compound; (2) carrying out a reaction on the chloroalkoxy phosphorus compound, glycidol, a second acidic catalyst and an inert solvent in a second microchannel reactor to obtain a hydroxy compound; (3) carrying out a ring-opening reaction on the hydroxy compound, epoxy vegetable oil, a basic catalyst and an inert solvent in a third microchannel reactor to obtain a vegetable oil polyol; and (4) carrying out an addition polymerization reaction on the vegetable oil polyol, propylene oxide and an inert solvent in a fourth microchannel reactor to obtain the polyurethane polyol.

A reactor system for high throughput applications includes a plurality of reactor assemblies, each reactor assembly including: a fluid source, which fluid source is adapted to provide a pressurized fluid to the flow-through reactors, a flow splitter which flow splitter includes a planar microfluidic chip, which microfluidic chip has a chip inlet channel and a plurality of chip outlet channels, which microfluidic chip further includes a plurality of flow restrictor channels, where each flow restrictor channel extends from said chip inlet channel to an associated chip outlet channel, where the chip inlet channel and the chip outlet channels each have a diameter, where the diameter of the chip inlet channel is the same or less than the length of said chip inlet channel and where the diameter of each chip outlet channel is the same or less than the length of said chip outlet channel.

A method for synthesising spherical material particles carried out in a continuous reactor. An intake tube is supplied with a solution A including at least one transition metal sulfate and the other intake tube being supplied with a solution B comprising hydroxide or a carbonate. The method includes delivering solutions A and B to a reaction tube at a flow rate d.sub.A and d.sub.B, and recovering the precipitated precursor at the outlet of the reaction tube. The length of the reaction tube and the delivery flow rates d.sub.A and d.sub.B are configured such that the residence time in the reaction tube is less than or equal to 10 seconds, wherein the pH in the reaction tube is 7 to 12 and wherein the regime in the reaction tube is a laminar regime.

A hydrogenation method for preparing HBPA includes placing a BPA reaction liquid into a hydrogenation vessel with a hollow-shaft stirrer installed inside; starting the hollow-shaft stirrer to stir the BPA reaction liquid and simultaneously allowing hydrogen gas evenly distributed over and contact well with the BPA reaction liquid; in the presence of a single-metallic Ru/Al2O3 hydrogenation catalyst to proceed with a catalytic hydrogenation at low temperature and low pressure to produce HBPA, the HBPA has a yield of 99.7% or more, and particularly having a trans/trans isomer ratio above 63%.

A reactor system for high throughput applications includes a plurality of reactor assemblies, each reactor assembly including: a fluid source, which fluid source is adapted to provide a pressurized fluid to the flow-through reactors, a flow splitter which flow splitter includes a planar microfluidic chip, which microfluidic chip has a chip inlet channel and a plurality of chip outlet channels, which microfluidic chip further includes a plurality of flow restrictor channels, where each flow restrictor channel extends from said chip inlet channel to an associated chip outlet channel, where the chip inlet channel and the chip outlet channels each have a diameter, where the diameter of the chip inlet channel is the same or less than the length of said chip inlet channel and where the diameter of each chip outlet channel is the same or less than the length of said chip outlet channel.