The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.

Embodiments in accordance with the present invention encompass an organoruthenium compound of the formula (I) or formula (II):

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Wherein X, L, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, Ar.sub.1 and Ar.sub.2 are as defined herein. Also disclosed herein are the use of organoruthenium compound of formula (I) or formula (II) as (pre)catalysts for the olefin metathesis reactions, as well as to the process for carrying out the olefin metathesis reaction.

The invention relates to monocarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The invention relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.

The invention concerns a new, efficient process for the preparation of enantiomerically pure norepinephrine (also known as noradrenaline), or an addition salt thereof, using a catalytic hydrogenation system under hydrogen donor transfer. The invention also discloses a novel intermediate and the process for the preparation thereof.

A hydroformylation catalyst, a preparation method thereof and a use thereof. The hydroformylation catalyst including an active component and a carrier carrying the active component, wherein the active component includes a transition metal as a center atom, and a polyhydroxy aromatic ring group bonded to the transition metal; and the transition metal and the polyhydroxy aromatic ring groups are bonded by at least one of metal-hydroxyl coordination bond and at least one of metal-oxygen covalent bond, and the active component has at least one of the metal-hydroxyl coordination bond and at least one of the metal-oxygen covalent bond.

A method of preparing an organosilanol compound is disclosed. The method comprises reacting (A) an initial organosilicon compound and (B) water in the presence of (C) a catalyst. The catalyst (C) is selected from: (C1) [(C.sub.8H.sub.12irCl].sub.2[(p-cymene)RuCl.sub.2].sub.2; and (C3) Pd/C. The initial organosilicon compound (A) has the general formula HO—Si(R).sub.2—[Si(R).sub.2O].sub.a—OSi(R).sub.2—Y and the organosilanol compound has the general formula HO—Si(R)2-[Si(R).sub.2O].sub.a—OSi(R).sub.2—Y, where each R is an independently selected hydrocarbyl group; Y comprises a functional moiety selected from alkoxysilyl moieties, epoxide moieties, and acryloxy moieties, with the proviso that Y is other than the acryloxy moieties when the catalyst (C) is (C3) Pd/C; and subscript a is 0 or 1. The organosilanol compound prepared by the method is also provided.

The invention relates to heterogeneous catalysts comprising an organo-ruthenium complex immobilized to an aluminum-modified inorganic oxide by a chemical bond between a tetra-coordinated aluminum atom on a surface of the aluminum-modified inorganic oxide and an amino or imino nitrogen of the organo-ruthenium complex, methods of preparing the heterogeneous catalysts including immobilizing the organo-ruthenium complex to a tetra-coordinated aluminum atom on a surface of an inorganic oxide by reacting an amino or imino nitrogen of the organo-ruthenium complex and an aluminum-modified inorganic oxide, followed by a defined heat treatment, as well as methods for producing hydrogen from formic acid using the heterogeneous catalysts.

The present invention relates to a transition metal complex having a PNNP4 ligand, which is easy to manufacture and handle and is relatively inexpensively available, and a method for manufacturing the same, as well as a method using this transition metal complex as a catalyst for hydrogenation reduction of ketones, esters and amides to manufacture corresponding alcohols, aldehydes, hemiacetals and hemiaminals, a method using this transition metal complex as a catalyst for oxidation of alcohols, hemiacetals and hemiaminals to manufacture corresponding carbonyl compounds, and a method using this transition metal complex as a catalyst for dehydrogenation condensation between alcohols and amines to manufacture alkylamines.

In a ruthenium complex compound according to the present invention, an NHC ligand has an excellent electron-donating ability to stabilize methylidene species due to the steric interaction between substituents having relatively different sizes. The ruthenium complex compound can improve selectivity when used as a catalyst due to having an asymmetric structure, and the activity of the ruthenium complex compound can be improved by adjusting substituents and additives. Accordingly, the ruthenium complex compound can be used as a catalyst in cross metathesis reactions including ethenolysis to produce desired compounds such as linear α-olefins at high yield, even under relatively mild conditions.

The present invention relates to the technical field of chiral synthesis, and specifically provides a new type of oxa-spirodiphosphine ligands. The bisphosphine ligand is prepared with oxa-spirobisphenol as a starting material after triflation, palladium catalyzed coupling with diaryl phosphine oxide, reduction of trichlorosilane, further palladium catalyzed coupling with diaryl phosphine oxide, and further reduction of trichlorosilane. The oxa-spiro compound has central chirality, and thus includes L-oxa-spirodiphosphine ligand and R-oxa-spirodiphosphine ligand. The racemic spirodiphosphine ligand is capable of being synthesized from racemic oxa-spirobisphenol as a raw material. The present invention can be used as a chiral ligand in the asymmetric hydrogenation of unsaturated carboxylic acids. The complex of the ligand with ruthenium can achieve an enantioselectivity of greater than 99% in the asymmetric hydrogenation of methyl-cinnamic acid.