A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.

Provided is a technique capable of easily performing a microbial test with high accuracy. A microbial test kit of the present disclosure includes: a first syringe capable of collecting a specimen and having a first syringe needle; a second syringe containing an ATP extraction reagent and having a second syringe needle; a sealed reaction container having a first opening, a first sealing member fitted to the first opening, a nozzle, a nozzle cap covering the nozzle, and a filter disposed so as to partition the first opening and the nozzle; a waste liquid container including a second opening and a second sealing member fitted to the second opening, and sealed under reduced pressure; and a luminescence measurement container that includes a third opening and a third sealing member fitted to the third opening, stores a luminescent reagent that emits light in presence of ATP, and is sealed under reduced pressure.

Disclosed is a centrifugable syringe and syringe components for use in blood fractionation. Also disclosed is a method of blood fractionation using the syringe. The syringe comprises a substantially transparent barrel, a substantially transparent, elongated delineation neck, a plunger for drawing blood into and expelling blood from the barrel, and an adapter attached to the neck for enabling releasable connection of a selected device over an inlet/outlet opening in the neck. The delineation neck extends away from a distal end of the barrel. The barrel and the neck have respective axial bores in fluid flow communication with each other, the cross sectional area of the bore in the delineation neck being substantially less than the cross sectional area of the bore in the barrel. The selected device may be one of various devices including a capping device sealing the inlet/outlet opening of the neck, a needle device used during withdrawal of blood from a subject through the neck, or a hose device used to carry away delineated blood fractions from the syringe through the neck.

A protector assembly for handling, storing and transporting donor tissue in a transfer pipette includes a distal cap and a proximal plug that are respectively engageable with opposite ends of the pipette. Structurally, the pipette includes a distally tapered fluid chamber which is in fluid communication with an extension tube. The distal cap is dimensioned for friction engagement with the fluid chamber of the pipette and it is formed with a plurality of vents to establish fluid communication through the vents with the fluid chamber. On the other hand, the proximal plug is dimensioned for a friction engagement with the extension tube to prevent leakage of solution from the fluid chamber of the pipette when the proximal plug is engaged with the pipette. In combination, an engagement of the protector assembly with a pipette holding a donor tissue will protect and preserve the donor tissue during handling and transport.

This invention provides a high-efficient single-cell collection method using a specially designed collection well and collection pipet tip for particle/cell collection from the collection well. The structures of the collection well and pipet tip eliminate fluidic dead volume in the collection, resulting in all (or most) of the particles/cells can be brought into the collection pipette tip with the flow. The advantages of this invention in cell manipulation include high cell collection efficiency, low cell damage and easy operation procedure.

Described herein are devices, systems, and methods to facilitate cryopreservation of a cell or a mass of a plurality of cells such as oocytes or embryos. A device of the disclosure can, for example, store oocytes or embryos during the vitrification and/or warming processes of in vitro fertilization.

An aid device, for manually emptying contents of a tube, including: a housing, a clamp, coupled to the housing and configured to secure a position of the tube in relation to the housing, wherein the tube includes a plunger configured to slide within the tube between an inlet end of the tube and an outlet end of the tube, a pusher configured to abut the plunger, and a lever pivotally coupled to the pusher by a first rotational axis such that the lever is continuously rotatable between an open configuration and a closed configuration about the first rotational axis, thereby facilitating a continuous movement of the pusher from the open configuration to the closed configuration, wherein the clamp is configured to secure the position of the tube such that the plunger of the tube is positioned between the outlet end of the tube and the pusher.

A fluid delivery device includes at least one area onto which at least one support element having at least one well may be placed in a defined position. The fluid delivery device further includes at least one pipetting device having a connector configured to releasably connect the at least one pipetting device with a disposable tip and with a fluid displacement element which enables aspiration and ejection of a defined volume of liquid to or from the disposable tip. The at least one pipetting element is movable in a vertical and preferably in at least one horizontal direction. The fluid delivery device also includes a blowing element that has at least one aperture coupled to a source of pressurized gas and is movable in a vertical and preferably at least one horizontal direction. A system includes such a fluid delivery device and the at least one support element.

The present disclosure relates to the field of liquid handling and dispensing systems in combination with additive manufacturing. In particular, it relates to temperature-controlled units, i.e. dispensing heads and source well holders, for receiving, holding and releasing liquid and semi-liquid material, liquid-handling and dispensing systems, apparatuses and methods for applying temperature-sensitive liquids. A temperature-controlled unit (1) comprises at least one Peltier element (3), each Peltier element having opposite first and second surfaces (4a, 4b). The unit (1) further comprises at least one cooling element (5). The at least one Peltier element (3) is arranged to have each respective first surface (4a) facing a reservoir block (2) of the unit (1). The at least one cooling element (5) is thermally connected to the Peltier element (3) and arranged to transfer heat generated by the at least one Peltier element (3) and dissipate the transferred heat away from the at least one Peltier element (3).

Misalignment of intersecting devices on a diagnostic instrument may be detected and remediated using a system comprising components such as an accelerometer, a plurality of strain gauges and a device comprising a processor and a memory (e.g., a computer). In such a system, the accelerometer may be adapted to detect movement of the diagnostic instrument. The device comprising the processor and the memory may be configured to, for each of the structural elements of the diagnostic instrument, determine whether an alignment change has taken place in that structural element based on analyzing measurements made by the plurality of strain gauges. The device comprising the processor and the memory may also be configured to, for each structural element where an alignment change is determined to have taken place, trigger a remediation for each device from a set of devices impacted by the alignment change of that structural element.