A dispensing device includes a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side.

A dosing device has a dosing tip for dispensing liquid medium and at least one pressure vessel with a pressurizing gas, in which an overpressure or a negative pressure can be set as a predefined pressure setpoint value of an internal pressure by a pressure regulator, the internal pressure set by means of the pressurizing gas acting on a first liquid medium. A bidirectional flow meter is provided to measure a quantity of the first medium that is moved by the internal pressure prevailing in the pressure vessel. Furthermore, a dosing valve is provided upstream of the dosing tip, which is adapted to enable or disable a flow of the first medium from the flow meter to the dosing tip. For precise dosing, the first medium is moved by means of a change in the predefined pressure setpoint value of the internal pressure of at least one pressure vessel, and the moved quantity of the first medium is measured by means of the flow meter.

A flow cell applicator system can include a flow cell applicator including multiple flow cells to deposit multiple substance spots on a deposition surface, and a positioning assembly to position, to dock, and to unlock the multiple flow cells relative to the deposition surface. The substance spots can be depositable when the multiple flow cells are docked on the deposition surface. The flow cell applicator system can also include a spot deposition identifier operably associated with a processor to: record data related to substance spots as applied on the deposition surface, identify data related to substance spots previously deposited on the deposition surface, or both.

The presently disclosed subject matter provides devices and methods for sample extraction from a swab during biological sample processing. In particular embodiments, the devices and methods are configured for use in conjunction with microfluidic devices for sample processing.

Fluid assembly for use in a fluid system, having a control module including a processing unit for processing control commands into individual electrical control signals with individually adjustable control signal levels and a control signal level electrically connected to the processing unit, with a power unit, which has a power module for converting the control signals into individual electrical control currents as a function of the control signal levels and an output interface electrically connected to the power module, wherein the processing unit is designed to provide a first group of control signals in a first time interval which can be individually predetermined for each control signal and to provide a second group of control signals in a second time interval which can be individually predetermined for each control signal and follows the respective first time interval, wherein the first control signal and the second control signal are selected in such a way that the control currents in the first time interval are greater than the control currents in the second time interval.

The present disclosure is directed to methods and devices for reducing or otherwise mitigating accumulated reagent material and/or fluids within a dispense nozzle of a dispenser.

The transfer systems, devices, kits, and methods described here may be used to facilitate the transfer of a material (e.g., a fluid) to or from a donor container, e.g., to or from wells of a donor plate while leaving target agents attached to the wells. The systems may comprise a donor plate, a transfer adapter, and a receiver plate that may be coupled to form a transfer assembly. The transfer adapter may comprise a planar sheet and a plurality of openings, and it may be configured to regulate the flow of fluid out of the wells. The transfer assembly may be placed into a centrifuge, and the fluid transfer force produced by the centrifuge may cause fluid to flow out of the wells of the donor plate, through the openings in the transfer adapter, and into the receiver plate.

An apparatus, system, and method combining a liquid transfer device with a non-contact liquid fill height sensor to improve the reliability, accuracy, and precision of liquid transfers and to determine liquid fill height and liquid volume in a container before or after liquid transfers.

A micropump for exchanging liquid between a supply region and a working region is provided. An enclosed gas region is located above the working region. The micropump includes a capillary pipette having a closed pipette tip on a first end, an open pipette inlet disposed opposite the first end, and a pipette section enclosing the working region and disposed in a direction of the open pipette inlet from the closed pipette tip. The micropump further includes a liquid-permeable filter covering the open pipette inlet and connected to the supply region. The micropump additionally includes a capillary structure extending through the gas region between the closed pipette tip and the liquid-permeable filter.

A container for a reactive product including a container body having a neck delimiting a neck opening; a closure member comprising a puncturable closure membrane which tightly seals off the neck opening; a suction tube located in the container body and comprising a first end portion attached to the closure member and a second end portion extending in the proximity of the bottom of the container body; and a cap attached to the neck and comprising a passage opening which is located facing the puncturable closure membrane and the first end portion of the suction tube, the cap being configured so as to enable the penetration of a sampling needle through the passage opening and the puncturable closure membrane such that the sampling needle is fluidly connected to the suction tube, and so as to enable the penetration of a venting needle through the passage opening and the puncturable closure membrane such that the venting needle is fluidly connected to an internal volume of the container body.