The present invention provides a sample tube for polymerase chain reaction. The sample tube includes a sample tube body having an annular side wall and a bottom wall connected to annular side wall, wherein the annular side wall and the bottom wall form an accommodating space for accommodating a reaction mixture; and a first extension member extending from the bottom wall to the accommodating space, wherein, to carry out PCR, the reaction mixture immerses the first extension member, such that the light from the light source enters into the reaction mixture via the bottom and the bottom wall of the sample tube and the first extension member sequentially.

The present application is directed to a sampling system for sampling a fluid from a vessel, where the sampling system includes a sterile dispenser assembly operatively connected to the vessel, the sterile dispenser assembly including a valve operatively connected to the vessel, a membrane, and a needle, and a detachable sterile sampling container assembly operatively connected to the sterile dispenser assembly, the detachable sterile sampling container assembly including a sampling container, a membrane attached to the sampling container, and a sampling container housing enclosing the sampling container, where the sampling container housing includes a compressible portion having a deflated configuration and an expanded configuration.

Devices and methods for performing pre-analysis sample processing of biological and chemical samples using robotic liquid handlers are disclosed. Methods for solid phase extraction, protein precipitation and filtration of biological and chemical samples using automation and the devices in a rapid and convenient way are described.

A microplate assembly for a plurality of samples includes a donor microplate having a plurality of sample donor cavities. The microplate assembly further includes a receiver microplate having a plurality of sample receiver cavities each sample receiver cavity having a transparent receiver bottom configured to enable microscopic imaging. In addition, the microplate assembly includes a leak-tight connecting structure configured to assemble the donor microplate and the receiver microplate, with at least one of the sample donor cavities being in communication with at least one of the sample receiver cavities. Further aspects are a receiver microplate and a leak-tight connecting structure for a microplate assembly as well as a method for transferring samples by means of a microplate assembly.

A device for determining contamination of a fluid by microorganisms has a housing with an internal volume, a cover closing the housing, a fluid inlet port, at least one filtration member, at least one nutrient layer including a composition of a microbiological culture medium, characterized in that the device includes a fluid outlet port, and in that the cover has an inner surface in the internal volume extending radially about the fluid inlet port up to a peripheral edge of the cover, said inner surface being inclined and converging towards the fluid inlet port, and in that the bottom of the housing has a surface extending radially about the fluid outlet port up to the side wall of the housing, said inner surface being inclined and converging towards the fluid outlet port.

A microtube assembly includes a column container, a sealing cap and a collecting tube. The column container includes a column body having a first protruding structure, and the one end of the column body has an opening and a first outer thread. The sealing cap has an inner thread matching up with the first outer thread, and the sealing cap is sealed the opening of the column container by the inner thread screwed on the first outer thread of the column body. The collecting tube includes a collecting tube body having a containing space and a matching structure corresponding to the first protruding structure. The containing space is configured for containing the column container. The matching structure leans against the first protruding structure when the sealing cap seals the column container.

The present disclosure relates to an apparatus, method, and system for separating a fluid sample. The apparatus for separating a fluid sample may include a receiving chamber comprising a first opening and a second opening. The first opening may have a larger diameter than the second opening. The apparatus may include a channel extending from the second opening of the receiving chamber. The channel may include a proximal end adjacent the receiving chamber and a distal end. The distal end of the channel may bifurcate into a first branch and a second branch. The first branch and the second branch can be inserted into a first container and a second container through a cap having an orifice to separate a fluid sample into the first container and the second container.

A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.

An adjustable volume sampling system is disclosed for aseptically retrieving a sample volume of a fluid from an origination container. The system includes a sampling container. A cap is removably attached to the sampling container so as to close off the open top. The cap includes two ports. A first tube is attached to one of the ports. An elongated diptube extends through port into the sampling container and an upper end of the diptube is located inside a portion of the first tube. The diptube can be raised and lowered relative to the sampling container by pinching an stretching the first tube. Syringes are provided for expelling excess material from the sampling container.

A reagent preparation device (also called sterile and safe reagent preparation device) is disclosed for preparing a solution of a reagent, particularly a toxic chemical. The sterile and safe reagent preparation device comprises a liquid storage for storing a liquid (solvent or other fluid reactant); and a reagent (chemical or other reactant) container for containing a reagent. The liquid storage and the reagent container are configured to be detachably engaged. A method of making the sterile and safe reagent preparation device and a method of using the sterile and safe reagent preparation device are also disclosed in the present application.