B01L2200/145

Microfluidic devices and related methods

A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.

BLOOD SAMPLE COLLECTION DEVICE WITH TIME STAMP AND SIMULTANEOUS ENVIRONMENTAL SAMPLE
20200121234 · 2020-04-23 ·

A blood sample collection device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect and optionally process the sample. A sample event detection circuit triggers a recording of a time when the sample was taken. The sample event detection circuit may determine when the housing is closed, or may detect the presence of blood in or near the sample port. The electronics may optionally record environmental conditions such as temperature or humidity, etc. at the time the sample is taken. The recorded data may then be used to enhance the value or accuracy of lab test, or for other purposes, such as inventory management.

Position indicator on liquid sample container
10526118 · 2020-01-07 · ·

A disclosed technique includes an assembly comprising a cup with a first visual sealing indicator and a lid with a second visual sealing indicator wherein, in operation, the lid is screwed on the cup to a sealing indicator position where the first visual sealing indicator and the second visual sealing indicator are aligned. Another disclosed technique includes an assembly comprising a cup with a first audible sealing indicator and a lid with a second audible sealing indicator wherein, in operation, the lid is screwed on the cup to a position past where the first audible sealing indicator and the second audible sealing indicator have contacted each other producing an audible sound. Another disclosed technique includes a cup with a raised central bottom area and an insert with bracing wings wherein, in operation, the bracing wings stabilize and secure the insert in the cup.

SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS

A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

Barrier isolator
10220382 · 2019-03-05 · ·

An isolator comprises a manipulation chamber isolated from the external atmosphere, a door for opening and closing a portal formed on the manipulation chamber, a linear guide mechanism for guiding a linear motion of a front-side edge of the door along the portal, and a rotation guide mechanism defining a rotation of the door about an axis coinciding with the front-side edge. The door is closed by positioning the front-side edge at the front side of the manipulation chamber, and the door is opened inward into the manipulation chamber by moving the front-side edge toward the back side while rotating the door about the front-side edge.

SEALED DOUBLE-DOOR CONNECTION DEVICE WITH REINFORCED SECURITY
20240278228 · 2024-08-22 ·

A sealed connection device for a double-door connection system comprising a first flange and a first door closing off the first flange, the first flange comprising bayonet connection for connecting an object, the object comprising a second flange closed off by a second door, the second flange being provided with n lugs intended to engage with the bayonet connection of the first flange, the first flange comprising n detectors of the correct assembly of the lugs of the second flange in the bayonet connection, each detector being configured to detect the presence of a lug.

Detection device for a sample detection
12090484 · 2024-09-17 · ·

The present invention provides a detection device for sample detection, where the detection device includes a device body and a device cover, the device cover is configured to cover the device body, the device body is spirally connected to the device cover, a signal apparatus is disposed between the device body and the device cover, a completely screwed state exists between the device body and the device cover, and when the device body and the device cover are in the completely screwed state, the signal apparatus makes a sound. The detection device is provided with a two-stage sealing apparatus and the signal apparatus. As the device cover performs covering, a first sealing apparatus first seals the device body and the device cover, and the signal apparatus makes a first sound, to prompt an operator that the detection device has completed primary sealing, which is suitable for short-distance and gentle-vibration transportation after sampling is performed by using the detection device. As the device cover continues performing covering, a second sealing apparatus seals the device body and the device cover again, and the signal apparatus makes a second sound, to prompt the operator that the detection device has completed secondary sealing, and covering no longer needs to be continued.

ADJUSTABLE TIPPING-PREVENTING TEMPERATURE-CONTROLLING TEST TUBE RACK FOR SMART MEDICAL TESTING
20180257079 · 2018-09-13 ·

The present invention relates to an adjustable tipping-preventing temperature-controlling test tube rack for smart medical testing comprising a stand, a temperature control mechanism, an adjustable stand, and a shaking mechanism. A slot rail, butterfly bolts and a magnet are disposed on the stand. The shaking mechanism comprises a heating plate mounted inside a chamber of the case and a micro pump connected to the chamber of the case. The shaking mechanism comprises a motor, a drive crank, a drive piece, slide rail and sliders. The adjustable stand comprises a stainless steel fixed piece, a magnetic adjustment plate, and supporting plates. The stainless steel fixed piece is connected to the magnetic adjustment plate. The test tube rack has the advantages of being reasonable, simple, convenient, fixedly mounted, good temperature control performance, good adaptability, high level of automation, precipitation preventing, can effectively solve the problem of the test tube rack tipping over easily.

MICROFLUIDIC DEVICES AND RELATED METHODS

A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.

SYSTEM AND METHOD FOR CONTROL OF CONTAMINANTS WITHIN LABORATORY CONTAINMENT DEVICES
20180056285 · 2018-03-01 ·

The present invention provides a measured containment control system fitted to a laboratory containment device 1. These devices can have a variety of coherent enclosure configurations in terms of size and geometry. User access to these devices can be by means of either an opening or the use of gloves with, in this latter case, typically filtration of the intake and exhaust ventilation. The system comprises further at least one sensor 6, an exhaust duct 5 or exhaust outlet connected to the laboratory containment device 1 for ventilation, an air flow control means 2 for controlling the exhaust air volume in the exhaust duct 5 and a control unit 13 connected to at least one sensor 6 and to the air flow control means 2. The control unit 13 is arranged to receive signals from at least one sensor 6 constantly and adjusting, based on these signals, the air flow control means 2 to change the exhaust air volume from the laboratory containment device 1.