A lateral flow assay (LFA) device includes a capillary pad and a sample port that holds the sample fluid before a hole is made in a cavity surface of the sample port. The LFA device includes a breaker with a tip to make a hole in the cavity wall of the sample port causing the sample fluid held inside the compartment to be applied to the capillary pad after the start of a test.

A container includes a vial, cap, and one or more wireless transponders secured to the cap, the vial or a jacket to store and identify samples of biological material at cryogenic temperatures (e.g., vitrified biological samples), for instance held by cryopreservation storage devices. A specimen holder may be extend from the cap. The vial and/or cap includes ports or vents. A carrier includes a box, thermal shunt, thermal insulation to store and identify arrays of containers that hold cryopreservation storage devices with samples of biological material at cryogenic temperatures. Various apparatus include wireless transponders positioned and oriented to enhance range, and allow interrogation while retained in a carrier. Various apparatus can maintain the biological material at or close to cryogenic temperatures for prolonged period of times after being removed from a cryogenic cooler, and can allow wireless inventorying while maintaining the biological samples at suitably cold temperatures.

A system (100) for storing, identifying and localizing supports (20, 21) for tissue samples embedded in paraffin, comprising—a plurality of supports (20, 21), wherein each one is provided with a respective RFID tag (201), said supports (20, 21) being each a histology cassette (20) configured to contain a tissue sample embedded in paraffin, or a slide (21); —a plurality of trays (1), wherein each tray (1) is provided with a respective RFID tag (101), and is configured to contain a plurality of said supports (20, 21), ach tray (1) being provided with a plurality of seats (11), each seat (11) being configured to receive a respective support (20, 21) and each support (20, 21) being adapted to be arranged at a respective seat (11); —at least one component (3) provided with a plurality of RFID antennas (10, 31), said plurality of RFID antennas (10, 31) comprising an RFID antenna (10) for reading the RFID tag (101) of a tray (1) of said plurality of trays, and RFID antennas (31) for reading the RFID tags (201) of the supports (20, 21); —at least one RFID interrogator (4); —one or more demultiplexers (5), by means of which the RFID interrogator (4) may be connected to each RFID antenna (10, 31) of said plurality of RFID antennas (10, 31), said one or more demultiplexers (5) being configured to sequentially activate a unique signal transmission line for each RFID antenna (10, 31) of said plurality of RFID antennas (10, 31); —an electronic control unit (6), configured to synchronize said one or more demultiplexers (5) and said at least one RFID interrogator (4) with one another, to sequentially read the RFID tags (210) of the supports (20, 21) and the RFID tag (101) of a tray (1) of said plurality of trays by means of one RFID antenna (10, 31) at a time, of said plurality of RFID antennas (10, 31).

The present technology provides for a fluorescent detector that is configured to detect light emitted for a probe characteristic of a polynucleotide. The polynucleotide is undergoing amplification in a microfluidic channel with which the detector is in optical communication. The detector is configured to detect minute quantities of polynucleotide, such as would be contained in a microfluidic volume. The detector can also be multiplexed to permit multiple concurrent measurements on multiple polynucleotides concurrently.

An apparatus for distributing medicines, vitamins and/or samples, including an organizer and dispensing units for medicines, vitamins and/or samples. The organizer includes seats in which to place the dispensing units. The apparatus includes an identification device connected to a data processing device and containing dispensing data on medicines, vitamins and/or samples, including detecting members controlled to a detecting state by detecting signals generated on the basis of dispensing data in the data processing device. The identification device is configured to be brought in connection with the organizer so that at least some of the detecting members are aligned with at least some of the seats of the organizer, wherein at least those dispensing units, which are aligned with at least one detecting member, can be identified by means of detecting signals generated on the basis of dispensing data in the data processing device.

A cartridge pre-processing device system and method receives immunoassay lateral flow assay test cartridges for development prior to submitting the cartridge for assay/analysis. The cartridge pre-processing device supports high assay throughput with reduced operator burden by automating device pre-processing timing steps without locking-down the reader that is used to perform the assay/analysis. The pre-processing device is operated in a walk-a-way mode. The pre-processing device is separate from the assay cartridge reader and is capable of automatically timing the development of an assay cartridge with minimal to no operator oversight. Additionally, the device disclosed herein is able to alert the operator when assay development is complete and when the assay has developed in excess of a predetermined flex-time associated with an individual cartridge.

An assembly for storing sample processing consumables can include a cover and a tray. The cover defines a cover cavity. The tray defines a first plurality of wells. The tray includes a first portion received within the cover cavity such that a press fit is formed between a first tray surface of the first portion of the tray and a first cover surface of the cover defining the cover cavity, thereby releasably coupling the cover to the tray. Each of the first plurality of wells contains a sample processing consumable. The assembly can be used to load sample processing consumables into a sample processing instrument.

A container includes a vial, cap, and one or more wireless transponders secured to the cap, the vial or a jacket to store and identify samples of biological material at cryogenic temperatures (e.g., vitrified biological samples), for instance held by cryopreservation storage devices. A specimen holder may be extend from the cap. The vial and/or cap includes ports or vents. A carrier includes a box, thermal shunt, thermal insulation to store and identify arrays of containers that hold cryopreservation storage devices with samples of biological material at cryogenic temperatures. Various apparatus include wireless transponders positioned and oriented to enhance range, and allow interrogation while retained in a carrier. Various apparatus can maintain the biological material at or close to cryogenic temperatures for prolonged period of times after being removed from a cryogenic cooler, and can allow wireless inventorying while maintaining the biological samples at suitably cold temperatures.

A method of classifying sample data for robotically extracted samples is disclosed. A specimen is received from a human subject with a potential infection of a first disease agents or a plurality of disease agents. The specimen includes genetic material collected from a human subject using a collection device and stored in a collection carrier. The specimen includes a unique identifier on the collection carrier. The unique identifier contains human subject descriptive data. The method classifies the human subject descriptive data to identify a second disease agent. The method extracts a sequence of genetic material from the specimen using an automated robot. The method determines a test result for the first disease agent as a function of the sequence of genetic material. A system comprising a computer device configured to classify sample data for robotically extracted samples is also disclosed.

Point-of-care biomarker assay apparatus arranged for measuring a presence or concentration of a biomarker in a sample, said biomarker assay apparatus comprising cartridge receiving means arranged for receiving at least one cartridge having multiple chambers designed for receiving a plurality of liquid media comprising said sample, labelled binding reagent, magnetic beads reagent and wash buffer, a sample distribution unit arranged for processing pipetting steps with said chambers, thereby providing a liquid reactant mixture in one or more of said chambers, a magnetic coil assembly arranged for applying a magnetic field to said liquid reactant mixture for separating biomarkers bound to said magnetic beads and said labelled binding reagent, from said reactant mixture, a photo detector or assembly arranged for measuring said presence or concentration of said labelled binding reagent, a control unit arranged for controlling said processing pipetting steps with said chambers, and for controlling said sample distribution unit along said chambers according to a test protocol, wherein said test protocol comprises an order of subsequent processing steps performed in said plurality of chambers to be processed by said sample distribution unit, said processing steps comprising one or more processing pipetting steps by the sample distribution unit and one or more processing incubation steps of the reaction mixture within any of the chambers wherein the control unit being programmed for performing multiple, distinct test protocols.