Patent classifications
B01L2300/028
Sample and reagent reservoir kits and liners with anti-vacuum feature
A pipetting reservoir kit includes a base, a disposable liner, and a lid. The disposable liner includes anti-vacuum channels on the bottom wall to prevent a pipette tip vacuum engaging the wall during aspiration. The groupings of anti-vacuum channels located on the bottom surface of the liner face upward into the basin that holds liquid samples or reagents. The groupings of anti-vacuum channels are spaced in an array 4.5 mm apart for a 384 pipetting head and 9 mm apart for a 96 pipetting head. The anti-vacuum channels also lower the required working volume for the liner and reduce liquid waste.
Specimen container for biological materials
A specimen container that includes a first cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein a fill line is placed at a predetermined location on the body section; a threaded winged section that is adapted to be attached to the second threaded end of the first cylindrical housing section, wherein the threaded winged section includes two gripping wings formed on opposite sides of the threaded winged section; a second cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein two gripping wings are formed on opposite sides of the second cylindrical housing section and are integral therewith; a threaded connector ring that is adapted to connect the first cylindrical housing section to the second cylindrical housing section; and at least one syringe plunger adapted for insertion into the first cylindrical housing section or the second cylindrical housing section.
Pipette with improved readability and toughness
A serological pipette has an elongated hollow tubular body having an optical transmission of 40 to 70% over a range of 390 to 700 nm. The pipette body is formed from a polymer composition that includes 5 to 30 wt. % poly(styrene-butadiene-styrene) and 70 to 95 wt. % polystyrene. The tubular body is formed by extrusion at a barrel temperature ranging from 400 to 500 F.
STRETCH BLOW MOLDED PIPETTE, AND SYSTEM AND METHOD FOR FORMING SAME
A stretch blow molding method may include fabricating a preform (e.g., by molding, optionally while a core pin rotates within a mold cavity), heating the preform to a softening temperature, stretching and thereby elongating at least a portion of the heated preform, blowing the elongated preform with pressurized fluid within a mold cavity, and cooling the resulting pipette. A system for fabricating a stretch blow molded pipette includes a first mold defining a mold cavity for producing a preform. A stretch rod drive unit is configured to move a stretch rod within an interior of the preform to form an elongated preform, and a second mold defines blow molding cavity and a molding surface to contain expansion of the elongated perform when subjected to blowing by supplying pressurized fluid to an interior thereof.
Capillary pressure re-set mechanism and applications
Many hand-held diagnostics are limited in their functionality due to the challenging physics associated with small dimensional systems. An example of this is capillary forces in hydrophilic systems, such as the tight retention of liquid passing through a small pore filtration membrane, or capillary force driven microfluidics where, to keep liquid flowing the dimensions of the system become so small that the flow rates are too low to be useful, or the manufacturing of such devices becomes uneconomical. This disclosure details methods to reset the capillary force condition to avoid the requirement of transient pressure spikes associated with the breakthrough pressure of small pore membranes, and avoid the necessity of extremely small microfluidic channels, which can be useful in applications such as filtration of whole blood to plasma using only suction pressure or passive capillary pressure.
Sample cup
A cup used to receive, hold, measure and pour liquids, such a specimens, such as for a medical assay, is described. The cup comprises an open receiving upper chamber, two or more open sample-directing channels, and an open, calibrated and marked measuring column. When sitting on a level surface, fluid flows freely from the upper chamber through the sample-directing channels into the measuring column. A foot is under each fluid-directing channel. The base of the measuring column functions as an additional, such as a third, foot. Cups nest, with the two feet of the upper cup sitting into two sample-directing columns of lower cup. The measuring column and upper chamber taper to permit nesting. If the cup is tipped, it rests on two of three of: the two feet and the base of the measuring column, and a point on a lower perimeter of the upper chamber, such that fluid will not spill.
MNS False Bottom Specimen Transport Tube
This application is for a false bottom specimen transport tube, to be utilized for laboratory serum/plasma specimen transport and storage. It has the capacity to hold 3 mL of specimen, with graduated markings every 0.5 mL for visual estimation of volume. The bottom section of the aliquot tube will mimic the weight of a serum/plasma separator blood collection tube that has been centrifuged and the serum removed, leaving the gel barrier and the clot. The bottom section will also be completely nontransparent, which will allow for accurate sample volume determination with laboratory automation systems utilizing serum level detectors. This will allow the MNS tube to be utilized as a primary specimen
Materials: Polypropyleneclearfor top section Polypropylenesolid colorfor bottom section Function: Mimic a primary blood collection tube: Serum/plasma specimens can be poured off of the primary blood collection tubes into the MNS false bottom tubes, then sent to a secondary location and loaded directly onto a laboratory automation system. Weighted to match primary blood collection tubes, therefor it can be centrifuged along with them without interrupting normal operation.
Allows for micro sampling without the risk of aspirating into the gel barrier.
Allows accurate measurement of sample by serum level detectors on laboratory automation systems, therefor eliminating the risk of analyzer probe crashes.
Solid color bottom section, will allow for color coding: Red=serum, green=Li plasma, purple=EDTA plasma
Child Resistant Bottle Closure System
The present application provides a child-resistant liquid dispensing closure apparatus, which includes a plunger and pipet, and preferably a dosage measuring system that is integrated that appears as the plunger is withdrawn from the pipet. The closure may be used for a bottle containing a liquid for oral administration of solutions, syrups, suspensions, elixirs, tinctures, concentrates, and the like.
Closed fluid receiving and sampling container
A closed fluid receiving and sampling container that enables transfer of valuable reaction liquid to a receptacle without risking loss of sterility. The sampling container has a dip tube subassembly with a shorter inlet tube bent towards the wall of the receptacle to prevent or reduce foaming, and a longer outlet tube used to drain the waste liquid once the magnetic beads are trapped by the magnet. The dip tube subassembly is injection molded in one piece and provides a sealed lid also with a vent tube therethrough to enable filling and draining the receptacle without removing the lid, thus keeping the process aseptic. The sampling container is especially useful in the context of magnetic bead separation processes.