A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.

There is provided a histology system that comprises a microtome configured to expose a face of a tissue block comprising a tissue sample embedded in an embedding material and remove one or more tissue sections from the sample, a hydration system configured to hydrate the tissue block by depositing a hydrating liquid on the face of the tissue block, and a transfer system configured to transfer the one or more tissue sections from the microtome to one or more slides. In some embodiments, the hydration system is configured to produce droplet condensation of the hydrating liquid and deposit the condensation on the face of the tissue block.

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

A two-piece assembly for sequential through-matrix processing of solutions and/or solids is provided, the assembly having an inner vial which maintains and holds the matrix and an outer vial which is configured to receive the inner vial at the upper or lower parked positions, to respectively allow or impede passage of the solution through the matrix of the upper vial. Captured molecules can be treated with enzymes and/or chemistries in situ in the matrix, and without the need for the use of strong chaotropic agents such as urea or detergents like SDS.

An inspection chip includes: a body part including a microchannel; and a liquid introduction part introducing liquid into the microchannel. The liquid introduction part includes: a liquid reception part; and a lid part capable of sealing the liquid reception part. The liquid reception part includes: a liquid storage part having an opening part in an upper part thereof; and a connection part connected to the microchannel from a bottom part of the liquid storage part. The lid part includes a protrusion part that protrudes so as to be housed in the liquid storage part.

A lid apparatus for a multi-chambered container. The lid apparatus has a top-lid that is hingedly attached to a bottom-cap. The top-lid includes one or more openings for fluid filling multiple passages that extend from the bottom-cap. A lower bottom-cap includes welding features for welding to the multi-chambered container. The bottom-cap further includes one or more auxiliary ports for injecting a reagent when the lid apparatus is in a closed configuration sealingly attached to the multi-chambered sample container.

A sample collection device including a collection tube at least partially defining a storage volume therein, a mouthpiece coupled to the collection tube, the mouthpiece defining a channel providing access to the storage volume, and a filter at least partially positioned within the channel, where the filter is configured to filter a sample as it passes through the channel and into the storage volume.

Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Devices, systems, and methods for storing and/or transporting bodily fluid samples are disclosed herein. In some embodiments, a device for storing and/or transporting a sample of bodily fluid is configured to receive a collection cartridge including a housing and a sample tray removably coupled to the housing. The device can include a base and a cover pivotally coupled to the base. The cover is movable relative to the base between.an open position in which the jig portion is accessible and a closed position in which the jig portion is inaccessible. The base can include a jig portion configured to (a) receive the collection cartridge and (b) decouple the sample tray from a housing of the collection cartridge.

The invention concerns a filtration assembly (1) for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly (1) comprises a ring-like membrane support (10) holding a filtration membrane (11), a cylindrical reservoir (20) of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support (10) to define a sample volume adjacent to the filtration membrane (11) on one axial side of the membrane support (10); and a drain member (30) removably and fluid tightly attachable to the membrane support (10) to define a drain channel space adjacent to the filtration membrane (11) on an opposite axial side of the membrane support (10).