The present invention relates to a multisystem for simultaneously performing a biochemical examination and a blood test or an immunity test, the multisystem including a multi-disc in which a biochemical examination unit, a blood testing unit and an immunity test unit are divided and formed in a fan shape based on a rotation center. There is an effect that it is possible to perform all of a biochemical examination for measuring concentration values of biochemical components of serum to diagnose vital functions, a blood testing for separating blood samples to measure and test the number and deformation of red blood cells or white blood cells, and an immunity test for measuring an antigen-antibody reaction of serum to diagnose and test cancer or viruses in one device at the same time by using the multi-disc according to the present invention.

Compositions and methods for separating a sample of whole blood or bone marrow aspirate into a fraction rich in at least one of platelets and pluripotent cells are provided. A sample of whole blood can be centrifuged in a collection tube comprising a separator substance formulated to settle between the PRP fraction and the at least one other fraction. Preferably, centrifugation is completed without substantial activation of platelets. Optionally, the separator substance could be hardened to form a solid barrier that allows removal of all or substantially all of the platelets in the PRP fraction without remixing of the PRP fraction with the at least one other fraction. Transfer devices and methods are also provided in which a sterile sample can be transferred from a separation/preparation container (e.g., vacutainer) to a consumer or other container (e.g., dropper) while maintaining sterility of the sample.

A reagent storage device of the present disclosure includes a shutter and a moving mechanism. The shutter is configured to open and close an opening in a reagent compartment for housing a reagent container, the reagent compartment being provided with the opening for insertion and removal of a probe used to extract a reagent from inside the reagent container housed in the reagent compartment. The moving mechanism is configured to move the shutter to an overlay position opposing the opening and separated from the opening before moving the shutter downward so as to close off the opening, and is also configured to move the shutter that is closing off the opening upward to open up the opening before withdrawing the shutter from the overlay position over the opening.

An oral care implement that includes a head having a face with a tuft hole therein. A plurality of bristles are disposed within the tuft hole and arranged in a bristle tuft that extends from the face of the head. The bristle tuft includes a first subset of the bristles and a second subset of the bristles. Each of the bristles has a longitudinal axis and a transverse cross-sectional profile having a major axis and a minor axis, the major axes of the bristles being longer than the minor axes of the bristles. The major axes of the bristles of the first subset may be non-parallel to the major axes of the bristles of the second subset.

A joint point-of-care testing (POCT) analyzer, and a system comprising an analyzer and a cartridge, for measuring one or more analyte quantities per unit volume of blood and one or more formed element quantities per unit volume of blood, is described. Examples of formed elements of blood are red blood cells and white blood cells, and cell counts are determined by imaging using a two-dimensional multi-channel detector. Examples of analytes are hemoglobin and bilirubin, and hemoglobin and bilirubin concentrations are determined by spectroscopy using a one-dimensional multi-channel detector. Other examples of analytes are electrolytes, and electrolyte concentrations may be determined using biosensors incorporated in the cartridges.

The present invention discloses a multi-function polymerase chain reaction device, which utilizes a movable multi-functional top cover to make an equipment can selectively perform variable temperature PCR (Polymerase Chain Reaction) or constant temperature PCR, which the flexibility of test-application is highly raised.

The present disclosure provides an assay cartridge used in a PCR-based molecular diagnostic device. In one embodiment, the assay cartridge comprises (1) an elongated body having a proximal end, a distal end and a plurality of compartments arranged between the proximal end and the distal end, said plurality of compartments include at least a first pipette tip holder near the proximal end, and a second pipette tip holder near the distal end; and (2) a seal assembly covering the elongated body comprising a rigid frame which matches the top periphery of the elongated body, and an elastic top mounted on the rigid frame, the elastic top comprising a first sub-portion near the proximal end comprising a first ring structure that matches the first pipette holder, and a second sub-portion near the distal end comprising a second ring structure that matches the second pipette holder.

The present technology provides for a fluorescent detector that is configured to detect light emitted for a probe characteristic of a polynucleotide. The polynucleotide is undergoing amplification in a microfluidic channel with which the detector is in optical communication. The detector is configured to detect minute quantities of polynucleotide, such as would be contained in a microfluidic volume. The detector can also be multiplexed to permit multiple concurrent measurements on multiple polynucleotides concurrently.

Apparatus and methods are disclosed for container lids, suitable for use in reliable automated handling and transport of lamella carriers used for transmission electron microscopy samples, or similar light or thin objects. A lid is for use with a container having one or more cavities that can be accessible through a top surface of a container. The lid can comprise a rigid member having a planar surface. Affixed to the rigid member are a first means for constraining motion of the planar surface to one-degree of freedom movement over the top surface, and a second means for restricting motion, within the cavity, of a lamella carrier contained within the cavity.

Some systems, devices and methods detailed herein provide a restraint device for holding a microslide or another slide instrument in an operative position in a petri dish.