This disclosure relates to an apparatus for simultaneously filling a plurality of sample chambers. In one aspect, the apparatus comprises a common fluid source and a plurality of independent, continuous fluidic pathways. Each independent, continuous fluidic pathway comprises a sample chamber and a pneumatic compartment. The sample chamber is connected to the common fluid source, and the pneumatic compartment is connected to the sample chamber. The sample chamber comprises, in part, an assay chamber. The assay chamber comprises a monolithic substrate and a plug having optically transmissive properties. In some embodiments, the assay chamber contains a magnetic mixing element. In some embodiments, the assay chamber is a double tapered chamber. In some embodiments, a ratio of a volume of the sample chamber to a volume of the pneumatic compartment is substantially equivalent for each fluidic pathway of the plurality of fluidic pathways.

The invention is directed to a slide chamber comprising a top member (10), a fluidic seal (20), a transparent closure member (30) and base member (40) wherein the top member (10) is provided with at least one examination chamber (11) and a plurality of openings (12) positioned at two sides of the cover member outside of the examination chamber (11); and the base member (40) is provided with interconnecting means (41) complementary to the openings (12) of the top member characterized in that the interconnecting means (41) of the base member (40) and the openings (12) of the top member (10) are configured to mechanically interlock with each other by lateral movement thereby pressing the top member (10) against the transparent closure (30) member in a water-tight manner.

A sample assembly includes a vial, a vial insert, and a sealing arrangement. The vial insert could be any combination of a sample chamber, a matrix, or a swab breaker configured to be positioned within the vial. The sealing arrangement includes a coupling portion and a cap assembly. The coupling portion defines a mounting channel sized to receive a portion of the vial. The coupling portion is configured to slidably couple to the vial. The cap assembly includes a desiccant cap. The desiccant cap is configured to couple to the vial to selectively form a sterile barrier between the sealing arrangement and the vial.

There is provided a sample processing cartridge comprising a. a sample entry location; b. a closed sample processing chamber; c. a sample analysis location comprising a sample analysis well; d. a first channel fluidly connecting the sample entry location and the sample processing chamber; e. a second channel connecting the sample analysis location and the sample processing chamber, the second channel comprising a closed or closable second channel valve;
wherein the sample processing chamber comprises a second channel port providing fluid connection between the second channel and the sample processing chamber, the second channel port being positioned in a sample accumulating region of the sample processing chamber.

There is also provided a sample processing system comprising the cartridge, and methods of use of the cartridge and processing system in a sample processing assay.

The present application discloses an antigenic detector, including: a pen holder and a pen cap. The pen holder includes: a test paper tube, a test paper assembled in the test paper tube, a test paper support, and a foam support installed on the front end of the test paper tube with a foam and a protective cover; the pen cap includes: a base, an aluminum foil assembled in the base, and an interior of the base forms a cavity into which a front end of the pen holder is inserted, and a reaction solution is sealed inside the cavity of the base by the aluminum foil; the protective cover is detachably installed on the front end of the test paper tube and covers the foam; the foam support is provided with a channel that communicates with an interior of the test paper tube.

An inspection chip includes: a body part including a microchannel; and a liquid introduction part introducing liquid into the microchannel. The liquid introduction part includes: a liquid reception part; and a lid part capable of sealing the liquid reception part. The liquid reception part includes: a liquid storage part having an opening part in an upper part thereof; and a connection part connected to the microchannel from a bottom part of the liquid storage part. The lid part includes a protrusion part that protrudes so as to be housed in the liquid storage part.

A biological sample reaction vessel comprising a reagent storage portion and a push rod movable relative to the reagent storage portion is provided. The reagent storage portion comprises at least one reagent containing cavity, and the reagent containing cavity is sealed by a sealing element; and the push rod is connected to the sealing element, and the push rod is used for cooperation with an external device to separate the sealing element from the reagent storage portion. In reaction, the biological sample reaction vessel cooperates with a test cassette. By inserting the biological sample reaction vessel into the external device, the reagent in the reagent storage portion can be released rapidly.

The present invention relates to a whole blood and fingertip blood testing device, including a blood collection structure and a testing chamber connected to and in fluid communication with the blood collection structure. The blood collection structure includes a collection rod, a capillary channel is arranged inside the collection rod, the bottom end of the capillary channel is located at the tail end of the collection rod, and the top end of the capillary channel is located in the middle of the capillary channel; and the collection rod is provided with a communicating hole connected to and communicated with the top end of the capillary channel. Moreover, the present invention also provides a method for collecting and testing a blood sample by using the testing device. Through the integrated structure of the blood collection structure, the testing chamber and the buffer chamber, the whole blood and fingertip blood testing device and method achieve functions of collecting, slowly releasing and testing the blood sample. The operation is easy, which reduces the difficulty of use by the operator. The number of times and time that the operator contacts the sample are effectively reduced, and the infectious possibility of the operator is reduced, so that the testing device is suitable for HIV testing, novel coronavirus testing, etc. The testing device and method have low requirements on the collected amount of the sample, and the collected amount is optimized from the milliliter level to the microliter level.

The present invention relates to a container assembly for collecting and transporting a tissue sample. The container includes a container having a chamber therein for receiving the tissue sample. The container assembly includes a cap configured to be attached to the container to close off the chamber. The cap includes a base section, which is configured to be attached to the container, and a movable section, which is movably coupled to the base section. The base section and movable section are configured to form a reservoir therebetween, the reservoir being sized and shaped so as to contain a preservation solution. The base section and the movable section are configured such that the preservation solution is discharged into the chamber from the reservoir when the movable section is moved relative to the base section from a closed position to an open position.

A system and method for automated single cell capture and processing is described, where the system includes a deck supporting and positioning a set of sample processing elements; a gantry for actuating tools for interactions with the set of sample processing elements supported by the deck; and a base supporting various processing subsystems and a control subsystems in communication with the processing subsystems. The system can automatically execute workflows associated with single cell processing, including mRNA capture, cDNA synthesis, protein-associated assays, and library preparation, for next generation sequencing.