B01L2300/0806

Base module and tray insert of a multipurpose tray for an automated processing system, multipurpose tray for an automated processing system, and method of simplified loading/unloading of a multipurpose tray into/from an automated processing system

The present invention describes a base module (100) and a tray insert (200, 300, 400) of a multipurpose tray (100) for an automated processing system, such as an analytical, pre-analytical or post-analytical processing system, as well as to a multipurpose tray comprising such base module and such tray insert, wherein the tray insert can be particularly used for holding a plurality of reagent or sample tubes to be processed in the automated processing system. The present invention further relates to a method of simplified loading/unloading of such a multipurpose tray into/from the automated processing system.

Analytical cartridge for soil testing and related methods

A rotary analysis apparatus and related methods are disclosed. The apparatus generally includes a rotary machine operable to rotate or spin a removable disk-type analytical cartridge. The cartridge includes a plurality of fluidly isolated processing trains for processing multiple samples simultaneously. Each process train includes an extractant mixing chamber, slurry filtration chamber, supernatant collection chamber, and reagent mixing chamber in fluid communication. In one use, soil sample slurry is prepared and added to the extractant mixing chamber. The slurry is mixed with an extractant by rotating the cartridge to separate out an analyte from the mixture. A sediment filter in the filtration chamber deliquifies and traps soil particles to produce clear supernatant. A color changing reagent or fluorescent agent may be mixed with the collected supernatant for subsequent colorimetric, fluorescent, turbidimetric, or other type of analysis.

Method for detecting aldehydes or ketones

A method for simulataneously separating and detecting aldehydes or ketones from a plurality of samples containing the samein a simple and rapid manner by using a rotary microdevice capable of integrating derivatization and TLC separation of aldehydes and ketones, and the method providing reliable TLC separation, control of moving speed of an eluent on a TLC plate, and improved TLC resolution.

A CYNADIDE DETERMINATION SYSTEM AND A METHOD FOR OBTAINING GOLD NANOCLUSTERS USED IN THE SYSTEM
20240302278 · 2024-09-12 · ·

The present invention relates to a system which enables to carry out cyanide determination in biological samples taken from the living beings who are exposed to cyanide gas and/or cyanide components especially released from the industry and/or house fires, and a method of obtaining gold nanoclusters used in the system.

SYSTEMS AND METHODS FOR INLINE, DUAL-STAGE SAMPLE DILUTION
20240299928 · 2024-09-12 ·

Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.

Micro-fluidic device for concentration of particles via centrifugal force, and corresponding centrifugation and/or detection device

A microfluidic device for concentrating particles contained in a fluid sample (FS) comprises a substrate (11) configured for being set in rotation about a centre of rotation (5a), the substrate (11) having a surface (11b) defined in which is at least one microfluidic arrangement (12) that extends substantially according to a plane identified by the substrate (11). The at least one microfluidic arrangement (12) comprises at least one microchannel (13) having a first end (13a) and a second end (13b), wherein: the at least one microchannel (13) comprises, in a region thereof intermediate between its first end (13a) and its second end (13a), at least one accumulation area (15) that is at a first distance (R1) in a radial direction (R) from the centre of rotation (5a) of the substrate (11); the first end (13a) and the second end (13b) of the at least one microchannel (13) are at second distances (R2) in a radial direction (R) from the centre of rotation (5a) of the substrate (11); and the first distance (R1) in a radial direction (R) is greater than the second distances (R2) in a radial direction (R), in such a way that particles (P) possibly contained in a volume of fluid of the fluid sample (FS) that penetrates into the at least one microchannel (13) tend to concentrate in the at least one accumulation area (15) as a result of the centrifugal force caused by a rotation of the substrate (11) about the centre of rotation (5a).

Relative humidity control apparatus

A relative humidity control apparatus for control of the relative humidity in a gas space has a nebulizer source with an outlet for nebulized liquid, a frame surrounding an open area and comprising an opening arrangement to the open area and in operational flow connection with the outlet, and a flow drive arrangement generating a gas flow from the outlet to and out of the opening arrangement. A liquid handling robot comprising this apparatus, a method of operating the apparatus, an immunoassay method and methods of controlling the time course of the relative humidity in a gaseous space and of producing a predetermined volume of a liquid are also disclosed.

Microfluidic structure, microfluidic device having the same and method of controlling the microfluidic device
10058864 · 2018-08-28 · ·

A microfluidic structure in which a plurality of chambers arranged at different positions are connected in parallel and into which a fixed amount of fluid may be efficiently distributed without using a separate driving source, and a microfluidic device having the same. The microfluidic device includes a platform having a center of rotation and including at least one microfluidic structure. The microfluidic structure includes a sample supply chamber configured to accommodate a sample, a plurality of first chambers arranged in a circumferential direction of the platform at different distances from the center of rotation of the platform, and a plurality of siphon channels, each of the siphon channels being connected to a corresponding one of the first chambers.

Particle detection using reflective surface
10060850 · 2018-08-28 · ·

An example assembly includes a target holder that retains a target in a detection region. A reflective surface reflects at least part of a focused spot of light to provide resultant light. An irradiation system irradiates at least part of the detection region with the focused spot of light. A motion system causes motion of the focused spot of light relative to the reflective surface. A detection system detects the resultant light. An example device, e.g., a lab-on-chip, includes a substrate, a sample inlet, and a reflective grating. The grating is retains a fluidic sample in a detection region fluidically connected to the sample inlet. The detection region is operatively arranged with respect to the reflective grating so that at least a portion of light passing through the detection region towards the reflective grating also passes through the detection region after reflecting off the reflective grating.

Microfluidic device

Disclosed herein is a microfluidic device, which includes a platform, at least one chamber provided in the platform to accommodate a sample, and at least one channel configured to couple the chambers to each other. The at least one chamber includes a detection chamber configured to detect the sample, and the microfluidic device further includes a light blocking portion configured to prevent external light from entering the detection chamber so as to prevent occurrence of errors in detection of the sample in the detection chamber. The microfluidic device can be useful for preventing the occurrence of detection errors which might otherwise be caused by interference of external light. The microfluidic device may also be useful for reducing an inspection time and for miniaturizing microfluidic devices. Further, the microfluidic device may be useful for preventing contaminants from entering the detection chamber.