A bench top incubator is described. The bench top incubator includes a first tray stack designed to retain microscope slides in a plurality of slide trays and a second tray stack designed to retain multi-well plates in a plurality of plate trays. The incubator is relatively simple and small in design and can be conveniently located to carry out temperature processing of biological samples such as fixed cells and tissues, biological fluids, and so forth.

A method and system for measuring the alignment between a substrate and a platform upon which it is disposed by using image processing algorithms are described herein. These algorithms automate the detection of edges of a microscope slide and the platform in a digital image. A reference line pattern in an image of the platform can be used to detect platform edges based on a computed location of the reference line pattern in the image.

A digital dispense system and methods for preparing samples for analysis. The digital dispense system includes a fluid droplet ejection system housed in a housing unit. The fluid droplet ejection system contains a fluid droplet ejection head and fluid cartridge containing one or more fluids to be dispensed. A cartridge translation mechanism is provided for moving the fluid droplet ejection head and fluid cartridge back and forth over a sample holder in an x direction. A sample tray translation mechanism moves a sample tray back and forth beneath the fluid droplet ejection head and fluid cartridge in a y direction orthogonal to the x direction.

The invention is directed to a slide chamber comprising a top member (10), a fluidic seal (20), a transparent closure member (30) and base member (40) wherein the top member (10) is provided with at least one examination chamber (11) and a plurality of openings (12) positioned at two sides of the cover member outside of the examination chamber (11); and the base member (40) is provided with interconnecting means (41) complementary to the openings (12) of the top member characterized in that the interconnecting means (41) of the base member (40) and the openings (12) of the top member (10) are configured to mechanically interlock with each other by lateral movement thereby pressing the top member (10) against the transparent closure (30) member in a water-tight manner.

Device, systems, and methods are provided that can be used to monitor, examine, and/or analyze hair conditions and make suggestions to improve the hair conditions.

The present disclosure relates to methods for preparing biological samples for in situ analysis of one or more analytes wherein the biological sample has been previously affixed to a substrate, which in some cases may not be compatible with in situ analysis, for example, due to the absence of positional markers and/or fiducial markers and/or a region suitable for in situ signal detection on the substrate. In some aspects, a hydrophobic adapter having positional markers and/or fiducial markers is applied to the substrate to which a biological sample has been affixed, thus enabling in situ sample processing and analysis of the biological sample. The hydrophobic adhesive label or adapter can be used for automated microscope alignment and sample preparation.

Methods for performing multiple omics analysis in parallel are provided, the methods can include: dividing the mixture of cells or cell components into at least a first portion and a second portion; performing a first analysis on the first portion to acquire a first set of analytical data; performing a second analysis on the second portion to acquire a second set of analytical data. Methods for forming mixtures of analytes into first and second portions are also provided. The methods can include aligning the first and second plates to engage the first exposed surface with the second exposed surface, wherein the engaging is sufficient to convey at least some of the first analytes into the second solution to form a second mixture of the first analytes.

The present disclosure provides a cell harvesting method for the efficient sedimentation and retention of cells from liquid samples onto a solid support with low cell losses and low impact on cell morphology.

The present disclosure provides apparatus and methods for handling slides. The apparatus includes a carrier comprising a retention hole and a cartridge having a case coupled to one or more separators that together define a plurality of compartments each configured to accept the carrier. At least one of the separators comprises a guide hole, with all guide holes are disposed on a first axis. The retention hole of the carrier is aligned with the first axis when the carrier is disposed in a seated position within one of the compartments. The cartridge also comprises a plurality of spacers each partially disposed within at least one of the guide holes.

The device for the storage and traceability of biological specimens placed in holders is provided with identification information in the form of encoded data. The device includes at least one tray provided with a plurality of cells for the storage of the holders provided with storage housings for the holders, at least one apparatus for reading encoded data and determining data relative to the location of each holder within the receptacle, and a computerized processor for the data read and determined by the apparatus. The is a device for recognizing an empty housing within the receptacle defined by a detector for a physical characteristic of the bottom of the cell or an element secured to this bottom.