A flow assay cartridge for housing and protecting a flow assay membrane or lateral flow test strip which can be vertically stacked and is adapted for high-throughput automated lateral flow assay testing and analysis. The flow assay cartridge comprises a base and lid for receiving the flow assay membrane, and top and bottom engagement features such that two or more flow assay cartridges can be releasably adjoined in a vertical orientation such that they can be easily handled by an automated assay apparatus.

The present invention provides a device for detecting whether an analyte is contained in a fluid sample; the device includes an absorbing element used for absorbing the fluid sample and a testing element, and fluidic communication between the testing element and the absorbing element may be controlled. By means of such a test device, quantitative detection can be achieved, and the liquid sample on the absorbing element can be prevented from flowing onto the testing element in advance to start test at the same time.

Lateral flow devices, methods and kits for performing lateral flow assays are provided.

An integrated testing device and fluid module are disclosed, as well as a method of manufacture. Fluid module contains a reservoir containing a test fluid, and a control vessel. The reservoir discharges test fluid into the control vessel, which discharges the test fluid in a controlled way to a test component.

Provided herein is a lateral flow diagnostic device and methods of using thereof. The device comprises a substrate and a first end, wherein the first end comprises a sample loading portion. The first end may further comprise a first region loaded with a detectable ligand, a CRISPR effector system, a detection construct, a first test band comprising a biotin ligand, and a second test band comprising a capture molecule for the detectable ligand. The detection construct may comprise an RNA oligonucleotide, having a first molecule such as FITC on a first end and a second molecule such as FAM on a second end. Contacting the sample loading portion with a sample causes the sample to flow from the sample loading portion of the substrate towards the first and second capture regions, thereby generating a detectable signal, which may be indicative of a disease state.

The present invention relates to a device and a method for qualitative and quantitative analysis of heavy metals and more particularly provides a device and a method for qualitative and quantitative analysis of heavy metals utilizing a rotary disc system.

An all-in-one self test kit includes: a test tool having a reagent container adapted to store a diagnosis reagent therein and a diagnosis kit with a casing constituted of a first body and a second body and a diagnosis strip disposed inside the casing and having a sucking part for sucking the diagnosis reagent and a diagnosis part reacting to the diagnosis reagent sucked to the sucking part; a sub-body having a container insertion portion for inserting the reagent container thereinto and a kit insertion portion for inserting the diagnosis kit thereinto; a main body for inserting the sub-body thereinto; and a cap fastened and unfastened with an entrance of the main body to open and close the main body.

The present application discloses an antigenic detector, including: a pen holder and a pen cap. The pen holder includes: a test paper tube, a test paper assembled in the test paper tube, a test paper support, and a foam support installed on the front end of the test paper tube with a foam and a protective cover; the pen cap includes: a base, an aluminum foil assembled in the base, and an interior of the base forms a cavity into which a front end of the pen holder is inserted, and a reaction solution is sealed inside the cavity of the base by the aluminum foil; the protective cover is detachably installed on the front end of the test paper tube and covers the foam; the foam support is provided with a channel that communicates with an interior of the test paper tube.

Disclosed is a sample collection and detection card. A lower cover of the card is provided with a sample loading chamber capable of accommodating a sampling part of a sampling end, an outlet is arranged at a bottom of the sample loading chamber, and a sample loading area of a test strip is located at the outlet; a fixing structure for fixing a sampling rod to a box is further arranged between the box and the sampling rod, and the sampling part is deformable when the sampling rod is fixed to the box. In embodiments of the present disclosure, the sample loading chamber is arranged on the lower cover, and the sample loading area of the test strip is arranged at the outlet of the sample loading chamber.

A rapid, low-cost, portable and reliable method for on-site detection of deoxynivalenol (DON), a representative mycotoxin predominantly occurring in grains, would be helpful to control mycotoxin contamination. Herein, a paper-based microfluidic chip capable of measuring deoxynivalenol (DON-Chip) in foods, feeds and feed ingredients was developed. As discussed herein, the DON-Chip incorporated a colorimetric competitive immunoassay into a paper microfluidic device and used gold nanoparticles as a signal indicator. Furthermore, a novel ratiometric analysis method was used to improve signal resolvability at low concentrations of DON. Detection of DON in aqueous extracts from solid foods, feeds or feed ingredients was successfully validated with a detection range from 0.01-20 ppm (using dilution factors from 10-10.sup.4). Compared with conventional methods, the novel DON-Chip greatly reduces the cost and time of mycotoxin detection in the food and feed industry.