An integrated fluid ejection and spectroscopic sensing system may include a fluid ejector to eject a droplet of fluid through an ejection orifice towards a deposition site, a sensor array, a dispersive element to project light onto the sensor array. The dispersive element, the sensor and the fluid ejector are joined as part of an integrated unit.

The invention provides devices for generating pre-templated instant partitions. The devices may include a shearing mechanism, such as a vortexer, a holder for holding a vessel containing a liquid onto the vortexer, and a temperature control unit for modulating a temperature of the vessel by convection. The invention also provides methods of using such devices to process analyte inside the pre-templated instant partitions.

A thermal cycler system for use with a sample holder configured to receive a plurality of samples includes a sample block having an upstanding peripheral side wall and being configured to receive the sample holder and an adaptor having an upstanding peripheral side wall configured to be positioned about the peripheral side wall of the sample block. When the peripheral side wall of the adaptor is positioned about the peripheral side wall of the sample block and the sample holder is received in the sample block, the peripheral side wall of the adaptor extends in an upward direction toward the sample holder.

A testing system collects a specimen from a subject and measures the collected specimen to test the specimen, and includes a box to allow at least one of specimen collection for collecting and receiving the specimen, preprocessing for processing the collected specimen before measurement, or specimen measurement for measuring the preprocessed specimen to be performed therein.

A multi-well assay plate is provided. The multi-well assay plate includes at least a top plate that defines a plurality of wells and a base plate having a substrate with well electrode structures patterned thereon. The well electrode structures are arranged in a plurality of sector electrical structures, each including a working electrode bus bar and a portion of an auxiliary electrode pattern. The substrate further includes at least one working electrode contact patterned on a bottom surface and an auxiliary electrode contact pattern disposed on the bottom surface.

An analysis unit for quantitating detection target substances bound to antibodies includes wells and inclination parts. The wells each have a hole-like shape defined by an opening, an inner circumferential surface, and a bottom. The inclination parts each have an inclined surface connected to the inner circumferential surface and inclined downward such that whose height with respect to the bottom decreases as a distance from an outer circumferential side of the well increases.

A method for producing a liquid reaction mixture containing a radioisotope, in particular, a radioactive composition, minimizes device contamination with radioactive substances and increase speed and accuracy with which droplets are mixed. The method for producing a radioactive composition includes placing at least one first droplet L1 containing a radionuclide and at least one second droplet L2 containing a labeling substance on at least two respective dimples 5 among dimples 5 on a front surface 4b of an insulating layer 4 of a liquid manipulation device 1, and obtaining a liquid mixture M by using a change in electrostatic force caused by changing voltage applied to the electrodes 3 to thereby cause a relative movement between the at least one first droplet L1 and the at least one second droplet L2 so that the at least one first droplet L1 and the at least one second droplet L2 are mixed together at any one dimple among the dimples 5.

An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with multiple receptacle wells. Each well has a through-hole extending from an inner surface of the well to an outer surface of the holder. A cover is rotatable between an open position and a closed position relative to the holder and is configured to exert a force onto any receptacles in the wells when the cover is in the closed position. The apparatus includes multiple optical fibers, and each of the optical fibers provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A thermal element is positioned between a thermally-conductive support and the receptacle holder.

Embodiments of the present invention provide systems and methods for tagging and acoustically characterizing containers.

An optofluidic diagnostic system and methods for rapid analyte detections. The system comprises an optofluidic sensor array, a test plate and an optical detection cartridge. The sensor array supports one or more distinct sensor units, each having a reactor section designed to temporarily enter a series of different kinds of wells in the test plate. One kind of well is a sample reservoir that holds reagent solution to be transferred into the reactor section. Another kind of well is a drainage chamber that removes reagent solution from the reactor section. A third kind of well is a colorant reservoir that holds a colorant reagent transferable into a reactor section. Finally, the sensor unit is transferred to the optical detection cartridge where it is placed into an isolation booth during the optical detection process so that its flat observation face is stationed in a viewing window opposite an optical detector lens.