A fluidic assembly comprising a fluid analysis apparatus (30), the fluid analysis apparatus (30) comprising: a fluid measurement device (34); a fluidic device including a flow cell (36) arranged in a measurement region of the fluid measurement device (34), the flow cell (36) constructed of at least one first fluoropolymer material, the flow cell (36) including a channel, the channel containing a sample segment (52) that is carried in a fluorinated fluid carrier (54), wherein the sample segment (52) and fluorinated fluid carrier (54) are immiscible.

An electric field gradient focusing device is provided that includes: (i) a fluidic channel having an inlet and an outlet for a fluid, (ii) a first actuator configured to induce a fluid flow in the fluidic channel from the inlet to the outlet via AC electroosmosis, and (iii) a second actuator configured to generate a DC electric field gradient along at least part of the fluidic channel.

Devices that can transport biological materials are described. The devices incorporate capillary channeled fibers that can effectively transport living cells as well as other biological materials such as nutrients, growth factors, waste materials, etc. The devices can include a sorptive material at one end of the fibers that can improve transport of materials through the devices. The devices can differentially transport different cell types, particularly when the fibers are held in a vertical orientation. Diagnostic devices that incorporate the capillary channeled fibers are described that can be utilized to separate cell types from one another. Tissue engineering scaffolds that incorporate the capillary channeled fibers are described that can more efficiently transport materials into and out of the scaffolds.

An apparatus for collecting liquid fractions from a separation/reaction apparatus (1). A capillary (2) guides an extracted liquid fraction to a branching unit (3), a collection arrangement (4) carries a plurality of target vessels (5) receiving the liquid fraction from the capillary and a fluid line (6) is flow-connected to a fluid pump (7) and opens into the branching unit. The capillary and the fluid line each have outlet openings in the direct vicinity of one another at their end facing a target vessel such that liquid emerging from the outlet opening (2′) of the capillary transitions into the outlet opening (6′) of the fluid line. This precludes back mixing with earlier/later liquid fractions, precludes uncontrolled dripping of sample substance at the transfer point, speeds displacement of the target vessels in the collection arrangement, facilitates automation of the fraction processing procedure, and results in a more compact fraction collection apparatus.

A measurement cell (3) for measuring at least one constituent of a liquid sample, in particular blood, includes a reception space (9) for receiving the sample includes a measurement system (8) having at least one sensor electrode (10) exposed within the reception space; a first heat supply equipment (12) extending over a first area (91); a second heat supply equipment (14) extending over a second area (93), the first and second heat supply equipment being arranged to heat the sample within the reception space (9), wherein the second area (93) is larger than the first area (91).

A droplet generating method includes the steps of providing a micro-pipe having an outlet end; providing a liquid driving device to generate a flow of a first liquid; locating and positioning the micro-pipe which extends along a vertical longitudinal axis; connecting the liquid driving device with the micro-pipe so that the first liquid flows and is emitted out from the outlet end; providing a container, which is positioned at least in-part below the micro-pipe and adapted to contain a second liquid including a liquid surface disposed at a position located between a highest and a lowest positions; and either vertically or horizontally vibrating the micro-pipe, and thereby forming a plurality of droplets of the first liquid emitted from the outlet end at a position below the liquid surface of the second liquid.

Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

A structure, apparatus, and method are disclosed. A silicon substrate with a microfluidic system that receives a sample fluid and prepares an analyte solution received by a reservoir containing a sensing surface is electrically connected to a semiconductor device. The structure includes a component for receiving a sample fluid, a component for preparing the sample fluid, a CRISPR system for cleaving a reporter species when the sample fluid contains a target sequence, a sorting component for separating the cleaved reporter species from the sample fluid and the CRISPR products, a cavity for receiving an analyte solution containing the cleaved reporter species, and a sensing surface in the cavity. The sensing surface detects electrical signals induced by reaction events in the analyte solution.

The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle.

A capillary chamber for performing chemical and physical analysis using a plurality of whole blood samples is presented. Following a loading of the whole blood samples into a plastic tube, the whole blood samples are distributed into a collection chamber and the capillary chamber has means of adding respective vaccines or similar biological products into each capillary tubes. The whole blood is then analyzed using standard microscopic techniques with sufficient resolution and contrast to record the chemical and physical properties of the blood immediately after withdrawal.