A sample preparation cartridge for use with a sample preparation device, the cartridge includes a housing defining plural separate segments, at least one of said segments comprising a fixed section of a pipette component; and a moveable head comprising a pipette tip, the head being configured, in use, to be moved between a position in which the pipette tip is in sealed engagement with the fixed section of pipette component and a position in which pipette tip is positioned adjacent to another of said plural segments. With the present invention a disposable sample preparation cartridge and corresponding analytical reader can be provided in a very cost effective and simple manner whilst still ensuring high quality sample preparation for analysis.

A cartridge comprises a housing; a sample mixing compartment disposed within the housing, the sample mixing compartment comprising: an activation pouch, and a sample collection region; and a gas transporter tube having a first end and a second end, the tube being disposed within the housing adjacent to the sample mixing compartment, wherein the sample mixing compartment is partially defined by a moveable door of the housing, the moveable door providing access to the sample mixing compartment when the door is in an open position and preventing access to the sample mixing compartment when the door is in a closed position; and wherein the door is configured to release contents of the activation pouch upon movement from the open position to the closed position.

Cell seeding devices and methods for utilization of the devices are described. The devices include a rolling needle support that carries a plurality of channeled needles thereon. Upon rolling the support over the surface of a scaffold, the needles penetrate the scaffold surface and deliver cells to the interior of the scaffold. The devices can deliver cells to a scaffold at a high density with high cellular retention and survival.

Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

The invention disclosed herein relates to a sample treatment device. The sample treatment device can include a bore comprising at least one chamber, wherein the at least one chamber, or multiple chambers, is formed by using partitions to define the chamber inside the device bore. The chambers can be formed by having a single shaft that is adapted to be moved longitudinally through the bore of the device, the shaft having sealing elements formed on or as part of the shaft, wherein the sealing elements create a seal with the interior bore wall, wherein the separate chambers defined by the interior bore wall and the sealing elements are formed by the spaces between the sealing elements. The chambers of the sample treatment device disclosed herein can be suitable for performing mixing, chemical reaction, heating, cooling, separation and/or washing steps using a simple to manufacture device, where one or all of the steps can be conducted for a desired or predetermined time.

A container may include a tubular sidewall defining interior and exterior surfaces of the container, and including first and second regions disposed relative to one another along a major axis of the tubular sidewall. The container further may include an identification mark embedded within the tubular sidewall at a plurality of sectors about the tubular sidewall within the first region. Each sector may have a width, and the identification mark is machine readable by a reader viewing any arbitrary one or more of the sectors. An exemplary method for preparing such a container is also provided.

Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

A system for concentrating cells, wherein a syringe comprises a lumen and an axial end comprising a port and a radial end closed to liquid flow. A plunger divides the axial and radial ends, and the syringe is configured to hold a cellular suspension. A filter disposed at the radial end is configured to maintain sterility of the syringe. A cap comprises a vent disposed at the radial end. The plunger is configured to be actuated towards the axial end by air pressure being applied into the radial end and the plunger is configured to be actuated towards the radial end by a vacuum being applied into the radial end.