B01L2300/0854

MNS False Bottom Specimen Transport Tube
20200391205 · 2020-12-17 · ·

This application is for a false bottom specimen transport tube, to be utilized for laboratory serum/plasma specimen transport and storage. It has the capacity to hold 3 mL of specimen, with graduated markings every 0.5 mL for visual estimation of volume. The bottom section of the aliquot tube will mimic the weight of a serum/plasma separator blood collection tube that has been centrifuged and the serum removed, leaving the gel barrier and the clot. The bottom section will also be completely nontransparent, which will allow for accurate sample volume determination with laboratory automation systems utilizing serum level detectors. This will allow the MNS tube to be utilized as a primary specimen

Materials: Polypropyleneclearfor top section Polypropylenesolid colorfor bottom section Function: Mimic a primary blood collection tube: Serum/plasma specimens can be poured off of the primary blood collection tubes into the MNS false bottom tubes, then sent to a secondary location and loaded directly onto a laboratory automation system. Weighted to match primary blood collection tubes, therefor it can be centrifuged along with them without interrupting normal operation.

Allows for micro sampling without the risk of aspirating into the gel barrier.

Allows accurate measurement of sample by serum level detectors on laboratory automation systems, therefor eliminating the risk of analyzer probe crashes.

Solid color bottom section, will allow for color coding: Red=serum, green=Li plasma, purple=EDTA plasma

Specimen tester including a separate initiator and method
20200384458 · 2020-12-10 ·

A specimen collection, storage, transport, and testing device can include an outer vessel containing an internal cup having an openable drain having a brim raised above the bottom floor of the cup. Once opened the drain allows a portion of liquid specimen to flow from the cup into a lower chamber of the vessel containing a number of chromatographic assay strips. A lid sealing the vessel can include a downwardly projecting guide tube having first barrier sealing a bottom aperture. An oblong initiator can axially engage the guide tube, break the first barrier and open the drain to initiate the test while retaining a pool of liquid specimen in the cup for subsequent confirmatory testing.

DEVICE FOR THE CAPTURE AND REMOVAL OF DISEASE MATERIAL FROM FLUIDS
20200378948 · 2020-12-03 ·

A device for the capture and adsorption of blood-borne materials of interest comprising a fluidic cartridge with at least one inlet and at least one outlet; a multidirectional fluidic channel between the at least one inlet and the at least one outlet; said multidirectional fluidic channel comprising at least one inner wall; and a substance coating at least a portion of the at least one inner wall of the multidirectional fluidic channel.

Device and process for automated extraction of nucleic acids
10851368 · 2020-12-01 · ·

A device and method are useful for automated extraction of nucleic acids. The device can include a body that can be immersed partly or completely in a reaction cavity, where the part immersed in the reaction cavity has a non-smooth surface. After lysis, an organic substance, preferably alcohols or ketones, can be mixed with a biological sample. This mixture can be brought into contact with a material with a non-smooth surface. Under these conditions, nucleic acids may be adsorbed on the surface of the material being used. Washing steps may be carried out. After drying, the adsorbed nucleic acid may be detached from the material by adding water or a buffer of low salt concentration, whereupon it can be used for downstream applications.

MICROFLUIDIC DEVICES WITH BUBBLE DIVERSION

A microfluidics device has one or more bubble diversion regions. Problems associated with the generation of air bubbles are avoided in a microfluidics device such as a cartridge, for use with a point of care (POC) diagnostics device, the cartridge being able to carry out downstream processing such as polymerase chain reaction (PCR) and/or nucleic acid capture. The bubble diversion region has a lower flow resistance than the flow resistance of an area of interest.

Device for Protecting an Inner Container
20200299048 · 2020-09-24 ·

A device for protecting an inner container and the sample or contents in the inner container. The device for protecting an inner container and sample includes an inner container and an outer protective body. The inner container can receive a sample for applications such as biomedical, health care, dentistry, agricultural, industrial, and veterinary. The inner container can be received into the outer protective body for protection. A lid secures over the inner container forming a seal to prevent leakage and contamination of the sample or inner container contents. The outer protective body is breakage-resistant for protection if the apparatus is dropped.

CRYOGENIC VIAL SLEEVE AND RELATED SYSTEMS AND METHODS
20200281191 · 2020-09-10 ·

A vial sleeve for a cryogenic vial includes a cover portion including a side wall defining a cavity for receiving at least a portion of the vial, and a locking feature configured to operatively engage at least a portion of the vial for resisting movement of the vial relative to the vial sleeve. The vial sleeve may include a first label adhered to an exterior surface of the side wall and including a first set of indicia. The first set of indicia may be different from a second set of indicia included on a second label adhered to an exterior surface of the vial.

Counting compartment and method for sample analysis
10768087 · 2020-09-08 · ·

The invention relates to a counting chamber for a microscope, adjustable in height. The method measures a cell count at two different chamber heights and deduces the concentration of particles without an exact calibration of the absolute height, as the height difference gives a measurement of the missing volume and therefore an estimate of the particle concentration.

Acid digestion instrument and vessel system

An instrument system for acid digestion is disclosed. The instrument includes a heating block, a reaction vessel formed of a polymer that is resistant to acid and other chemical attack at temperatures above 150 C. and that has a structure (thickness, etc.) sufficient to withstand pressures above atmospheric, a metal sleeve surrounding the polymeric reaction vessel, and an opening in the block that has a cross-section corresponding to the cross-section of the metal sleeve.

Container for biological preservation at low temperature
10745186 · 2020-08-18 · ·

A container is provided in the present disclosure. The container includes at least one outer wall that is made of a low temperature tolerant material where the at least one outer wall is arranged to substantially form the container with an opening end; a tube that is situated inside the at least one outer wall, where the tube and the at least one outer wall are substantially thermally insulated, and the tube is open at one end that is on a same side of the opening end of the container; and a container cover being shaped substantially to match the at least one outer wall, where the container over is capable of covering the opening end of the container.