The invention relates to thermal cycling device comprising: a sample location; a first heating means, wherein advantageously said first heating means is a contact heating means; a second heating means, wherein said second heating means is configured to bring said sample to a second temperature by directing electromagnetic radiation to the first light pipe section end and the light pipe section is configured to direct said electromagnetic radiation through its second end to the sample location, its uses and methods based thereon.

A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder containing biological sample. Each flow cell also may be configured to be selectively placed in an open position for positioning the at least one sample holder into the flow cell and a closed position for reacting biological sample contained in the at least one sample holder. The plurality of flow cells may be configured to be selectively placed in the open position and the closed position independently of each other.

Provided are a temperature control system, a detection system and a temperature control method for a micro-fluidic chip. The temperature control system includes a circuit structure in a functional layer of the micro-fluidic chip, corresponding to a reaction zone of the micro-fluidic chip, and including at least two thermistors and an input port and an output port, wherein the input port and the output port are electrically coupled through the thermistors to form an application circuit; and a controller electrically coupled to each port and configured to select a first input port and a first output port, such that the circuit structure is configured to form a first application circuit as a heating device, and to select a second input port and a second output port, such that the circuit structure is configured to form a second application circuit as a temperature sensor.

A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of one of the substrate layers, and a printed substrate layer that is bonded to or printed on one substrate layer of the at least one substrate layer. The printed substrate layer includes a heater printed on the printed substrate layer so as to align with at least a portion of the microchannel. The heater includes two electrodes aligned on opposite sides of the microchannel, and a plurality of heater bars electrically connecting the two electrodes. The plurality of heater bars includes a central heater bar disposed between outer heater bars.

A jet injection system (10) comprising (i) a microfluidic device (100) for jet ejection and (ii) a laser-based heating system (200), wherein: —the microfluidic device (100) comprises a hosting chamber (110) defined by a chamber wall (120), the hosting chamber (110) having a chamber height he selected from the range of 5-400 μm, a chamber width we selected from the range of 2hc-10hc, and a chamber length l.sub.c defined by a first chamber end (111) and a second chamber end (112), wherein the second chamber end (112) comprises a first chamber opening (131) for jet ejection from the hosting chamber (110), and wherein the hosting chamber (110) is configured to host a liquid (50); —the laser-based heating system (200) is configured to provide laser radiation (201) to one or more of the chamber wall (120) and a liquid (50) in the hosting chamber (110).

1. A method of performing an acoustophoretic operation comprises the steps of: i. providing a fluid, ii. positioning the fluid in a microfluidic cavity, iii. subjecting at least one portion of the fluid, in the microfluidic cavity, to an acoustic wave, and iv. providing, in at least one first region of the at least one portion, a thermal inhomogeneity whereby the temperature of the fluid in the at least one first region differs from the temperature of the fluid in at least one second region of the remainder of the at least one portion. A microfluidic system is also disclosed.

A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of one of the substrate layers, and a printed substrate layer that is bonded to or printed on one substrate layer of the at least one substrate layer. The printed substrate layer includes a heater printed on the printed substrate layer so as to align with at least a portion of the microchannel. The heater includes two electrodes aligned on opposite sides of the microchannel, and a plurality of heater bars electrically connecting the two electrodes. The plurality of heater bars includes a central heater bar disposed between outer heater bars.

A flow control and processing cartridge used in a nucleic acid analysis apparatus includes a cartridge body and a reaction chip. The cartridge body includes plural chambers for storing at least one sample and plural biochemical reagents and buffers, and plural channels connected with the plural chambers. The reaction chip is in conjunction with the cartridge body and includes plural detection wells, at least one main fluid channel connected with the detection wells and adapted to dispense the sample into the detection wells, and at least one gas releasing channel connected with the detection wells and adapted to release gas from the detection wells.

A Polymerase Chain Reaction (PCR) device used to detect infectious agents and certain diseases. The device provides a quantitative PCR that amplifies the target DNA sequence, while monitoring the amplitude of signal originating from DNA-intercalating probes, typically fluorescence, to quantify the amount of DNA being amplified. The device is used in combination with other medical devices to obtain the user's physical exam data. A combination of the PCR machine and above-mentioned other instruments with a network communication device (TOTUS) sends the physical exam and PCR information to servers, and/or physicians, pharmacists and other medical professionals to provide AI decisions.

The invention relates to a heating device for a rack of a diagnose robot comprising: -a polygonal, oval or cylindrical ring (221) defining a polygonal, oval or cylindrical closed wall, having a bottom opening (222) and a top opening (223) -wherein the bottom opening matches the size and form of a filter membrane and/or supporting body (2, 3) of a carrier (1) of a filtration assembly; and -one or more heating elements (224) selected from -a heating element which is integrated into the ring, -a heating element which is arranged on the outer and/or inner surface of the wall defining the ring, and -a heating element arranged in or on a lid, wherein the lid matches the size and form of the opening of the ring.