A lateral flow assay (LFA) device includes a sample port that holds the sample fluid before a hole is made in a wall of the sample port. The LFA device includes a cap with a sealer. The sealer fits inside the sample port after the sample port receives the sample fluid, forms a compartment for holding a predetermined volume of sample fluid between the sample port's wall and the sealer, and pushes any amount of sample fluid in excess of the predetermined volume out of the compartment after the cap is fitted inside the sample port. The LFA device includes a breaker with a tip to make a hole in the wall of the sample port causing the sample fluid held inside the compartment to be applied to the capillary pad after the start of a test.

The disclosed embodiments related to an apparatus and methods for biological sample processing enabling isolation and concentration of microbial or pathogenic constituents from the sample. Sample may be obtained directly from a specimen container, such as a vacutainer, and processed directly without risk of user exposure. The disclosed methods and apparatus provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.

A system for analysis of a sample to aid in diagnosis and/or detection of the presence or absence, and/or the identity of, an analyte in the sample is provided. A cartridge with reagents to isolate nucleic acid from a sample inserted in the cartridge and to amplify the isolated nucleic acid, and an instrument that interacts with the cartridge, together provide a self-contained sample to answer system for detection, identification, differentiation and/or quantification of a target nucleic acid in a sample.

Provided is a biological fluidic system that provides a high degree of sterilization by performing the biological processing in a closed system in which the fluid is contained in chambers that are isolated from the environment in a manner that does not permit ingress of contaminants.

A reacting device of dual path synchronous immunochromatographic platform includes a seat, an upper housing, and a fluid dividing funnel. The seat contains two immunochromatographic carriers. The hollow pipe portion has two sloped structures. A force bearing portion of the fluid dividing funnel can be pressed down, so two fluid exits of the fluid dividing funnel move towards these two sloped structures. The specimen drops and is guided into these two immunochromatographic carriers respectively. A reaction result can be observable. The fluid dividing funnel can divide the specimen into two immunochromatographic carriers evenly. The sloped structure can increase the accuracy of specimen supply. Excess specimen can be scraped off for enhancing the solving accuracy. In addition, it can decrease the possibility of false positive problem.

A sample analysis substrate capable of holding a plurality of liquids. The sample analysis substrate has a microchannel structure for transferring a liquid through rotary motion, the sample analysis substrate including: a substrate body having a rotation axis; a first and a second container holding a first and a second liquid therein; a first and a second accommodating section accommodating the first and the second container; and a cap having a first and second projection and movably supported on the substrate body. As the cap moves, the first drive projection and the second drive projection move the first container and the second container with staggered timing, thereby releasing the first and the second liquid accommodated therein.

Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.

A purpose is to provide a monitoring system to monitor whether there is a substance to be monitored in the air, and a detecting device used in the monitoring system. The monitoring system includes a detecting device, an analyzing device, and an abnormality notification system. The detecting device determines whether the air is in an abnormal state on the basis of an output signal from an abnormality detection sensor, pours liquid to be inspected, into which the air is sucked and liquefied, into a previously-installed reagent container when determining the abnormal state, generates mixed liquid in which a reactant in the reagent container and the poured liquid to be inspected are mixed, and drops the generated mixed liquid to an electrode of the analyzing device. The analyzing device determines existence/non-existence of a substance to be monitored on the basis of the mixed liquid dropped to the electrode, and gives a predetermined notification to the abnormality notification system when determining that there is the substance to be monitored. The abnormality notification system gives a predetermined notification when receiving the notification from the analyzing device.

The present invention relates to sample-to-answer systems, devices, cartridges, and method of using the same for detecting the presence of microorganisms in a sample, such as bacteria.

A device includes: a first portion configured to be grasped by the hand of the user, and a second portion defining a reservoir containing a control material, wherein the control material contains a target analyte in a known or predetermined concentration. A method of verifying the accuracy of an analyte monitoring device includes receiving a fluid sample, identifying the fluid sample as a control solution, and analyzing the fluid sample.