A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.

A system for buoyant separation includes a separation container. Additionally or alternatively, the system can include an automated instrument, one or more processing components, and/or any other components. A method for buoyant separation can include any or all of: manipulating the separation container; adding materials to the separation container; removing materials form the separation container; otherwise processing the separation container; and/or any other processes.

The disclosed apparatus, systems and methods relate to sample preparation and shipping technologies in a single shippable container. The shipping container contains a single use centrifuge. The centrifuge can be temperature controlled and meets all standards and regulations for the shipping and transport of biological specimens.

A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.

Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency.

A rotor 10 of a centrifuge 100 having a rotor axis R, a receiving space 18 for samples to be centrifuged, a lid 40 which limits the receiving space 18 at the top, which is concentrically mounted relative to the rotor and which has, on its side remote from the receiving space 18, a handle 44 for carrying the rotor and the lid 40, and a locking mechanism of lid 40 and rotor, which mechanism is mounted in a support 52, 54 in the lid 40, said locking mechanism 50, 34b comprising a locking element 50 adapted to be movable between a locking position and an unlocking position and which has an actuating member 56 and a latching element 58, with the actuating member 56 and the latching element 58 being axially spaced from each other relative to the rotor axis R. The invention is characterized in that the locking element 50 is formed by a tilt lever which has the actuating member 56 mounted on its upper end and the latching element 58 mounted on its lower end, with its pivot axis being aligned perpendicular to the rotor axis R.

A rotor 10 of a centrifuge 100, having a receiving chamber 18 for samples to be centrifuged, a concentrically mounted seat 20 which is associated with a support 106 of a drive shaft 104 of said centrifuge 100, a lid 40 which limits the receiving chamber 18 at the top, which is mounted concentrically relative to the rotor and which has, on its side remote from the receiving chamber 18, a handle 44 for carrying the rotor and the lid 40, and a locking mechanism 50, 34b of lid 40 and rotor, which locking mechanism 50, 34b comprises a locking element 50 which can be moved between a locking position and an unlocking position thereof. In accordance with the invention, part of the handle 44 is adapted to be movable and is operatively connected to a retaining element 48b, 48c, which retaining element 48b, 48c can be moved, by the handle 44, between a first position which prevents actuation of the locking element 50, and a second position which releases the locking element 50.

Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency.

Provided herein are devices and methods for sample isolation comprising a planar member configured to rotate around a bearing, and a plurality of apertures positioned at an angle to the planar member. Exemplary embodiments relate generally to the field of sample isolation, and more particularly to sample isolation using centrifugal and magnetic forces.

A device for use in a laboratory and operable as both a centrifuge and a magnetic stirrer includes a housing defining a cavity therein, a motor coupled to the housing, and a spindle driven by the motor and rotatable about a first axis. The device also includes a first rotor removably couplable to the spindle and configured to support at least one tube therein, and a second rotor removably couplable to the spindle and including at least one magnet. The device also includes a controller in communication with the motor and operable in a first mode of operation when the first rotor is coupled to the spindle and operable in a second mode of operation when the second rotor is coupled to the spindle.