The object of the invention is a print head for three-dimensional printing comprising an extrusion assembly (1) functionally coupled to a drive assembly (3), and a nozzle assembly (2), functionally coupled to the extrusion assembly (1), providing filament (10) transfer, wherein there is a cooling assembly (18) disposed between the extrusion assembly (1) and the drive assembly (2), containing a fluid cooling system, comprising an inlet (15), an outlet (17) and a system of cooling ducts (14) disposed inside the cooling assembly (18), distributing the cooling medium (11), providing maintenance of the preset temperature of the extrusion assembly (1) and the drive assembly (3). The object of the invention is also a print head assembly.

A method of manufacturing three-dimensional (3D) objects is provided. The method includes generating a plan for printing a plurality of 3D objects in a 3D printing medium at least in part by identifying an unprinted area of the 3D printing medium for insertion of a cooling device and determining where at least some of the plurality of 3D objects are to be printed in the 3D printing medium such that none of the at least some of the plurality of 3D objects, when printed, intersect the identified unprinted area for the insertion of the cooling device. The method further includes printing, using a 3D printer, the at least some of the plurality of 3D objects in accordance with the plan and, after the printing, inserting the cooling device into the unprinted area of the 3D printing medium and cooling the 3D printing medium using the cooling device.

A manufacturing apparatus for use in the low-temperature high-speed manufacturing of a support structure is introduced. The support structure thus manufactured is for supporting a low-temperature manufacturing scaffold for use in tissue engineering. The manufacturing apparatus includes a frame; a ring-shaped thermally conductive member disposed on the frame; a thermally conductive platform disposed centrally at the ring-shaped thermally conductive member and having an edge in direct contact with an inner wall of the ring-shaped thermally conductive member, wherein a space is defined by and between the thermally conductive platform and the ring-shaped thermally conductive member; a low temperature generating mechanism connected to the ring-shaped thermally conductive member and the thermally conductive platform to cool down the ring-shaped thermally conductive member and the thermally conductive platform; and a spray member disposed above the thermally conductive platform to spray a support material into the space.

Machine (10) for the temperature control of part of an industrial plant adapted for the formation of a product, comprising at least one thermoregulating hydraulic circuit (11) adapted to be operationally connected with a part of an industrial plant adapted for the formation of a product, wherein a thermoregulating liquid circulates in said hydraulic circuit (11); said hydraulic circuit comprisinga recirculating pump (12) for the thermoregulating liquid, of the variable flow type,downstream of the pump (12), a section (13) for delivery of the thermoregulating liquid from the hydraulic circuit (11) to the product formation part (B) of an industrial plant,a section (14) for returning the thermoregulating liquid from the product formation part (B) of an industrial plant to the hydraulic circuit (11),a heat exchange unit (15) for the thermoregulating liquid, placed between said return section (14) and said pump (12), wherein the thermoregulating liquid is thermoregulated, said machine (10) further comprising an electronic control and management apparatus (30), in which there is set at least one value for the operating temperature of the thermoregulating liquid and at least one predetermined time-based pump flow rate variation profile, according to which, upon receipt of a synchronization signal at a predetermined moment of the industrial process of product formation in the part (B) of the plant to be thermoregulated, the pump (12) moves the thermoregulating liquid with a variable flow rate based on said predetermined time-based flow variation profile.