A method for manufacturing a medical patch for the treatment of chronic vascular and diabetic ulcers comprises the steps of preparing a tubular support, spraying toward the axial lateral surface of said support at least two separate, simultaneous, converging jets of two nebulized solutions containing fibrinogen and thrombin, respectively, rotating the support and/or orienting the jets in such a way as to deposit on said support a layer of material (M) of predetermined size, and incubating the material (M) until the fibrin contained therein is polymerized.

Simulated tissue structures for practicing surgical techniques and methods of manufacturing those structures are provided. In particular, a realistic organ model or simulated tissue portion for practicing the removal of a tumor or other undesired tissue followed by suturing a remnant defect as part of the same surgical procedure is provided. The simulated tissue structures include a polyp simulation having a suturable mesh layer that is separable from a defect layer. A simulated colon model with interchangeable and suturable tissue pods is also provided as is a fully suturable rectum model and a rectum model with integrative suturable and removable polyp zones.

Apparatus for producing a three dimensional nanofiber structure includes (1) at least two spaced electrodes; (2) a spinner adapted to rotate the at least two spaced electrodes; (3) a syringe assembly adapted to eject a polymer solution from a syringe of the syringe assembly towards the at least two spaced electrodes while the at least two spaced electrodes are rotated by the spinner; and (4) a power supply assembly for providing the two spaced electrodes at a first electric potential, and for providing the syringe at a second electric potential which is different from the first electric potential. A composition of matter may include (1) a least one layer of nanofibers in which a distribution of angles of fibers is aligned; and (2) at least one gel layer, wherein the at least one layer of microfibers and the at least one gel layer alternate to form a laminate.

A breast implant device product that mimic the natural pectoral fat pad of the breast and is characterized by an incomplete pyramid with isosceles triangular base and wedge-shaped edges and sloping faces that meet at acute angles with variable degree located medially, laterally and on the top and a footprint characterized by a semicircular lower portion and an oval paraboloid upper portion and a center of gravity located closer to the base than to the profile, the said footprint is advantageously converging and moving towards the underlying surface as the chest wall with a method of manufacturing and a method of use of the said implant including a breast pyramid sizing system.

A process for the manufacture of a heart valve of polymer material which provides for the deposition of a polymer solution comprising a copolymer which is preferably a copolymer of poly(carbonato-urethane) fluoridate (F-PCU) and intracatenary polydimethylsiloxane (PDMS), a PDMS with a functional group outside the chain and a solvent onto a mould using a spray technique associated with phase inversion.

A breast implant device product that mimic the natural pectoral fat pad of the breast and is characterized by an incomplete pyramid with isosceles triangular base and wedge-shaped edges and sloping faces that meet at acute angles with variable degree located medially, laterally and on the top and a footprint characterized by a semicircular lower portion and an oval paraboloid upper portion and a center of gravity located closer to the base than to the profile, the said footprint is advantageously converging and moving towards the underlying surface as the chest wall with a method of manufacturing and a method of use of the said implant including a breast pyramid sizing system.

A method for producing a polyimide tubular member includes preparing a polyimide precursor solution, heating the polyimide precursor solution, coating a core with the heated polyimide precursor solution to form a coating film, drying the coating film, and baking the dried coating film to perform imidization.

The present invention refers to a process and apparatus for manufacturing plastic articles through the rotational molding method, and is more particularly addressed to a process and apparatus of rotomolding in furnace for manufacturing containers with multiple layers. The apparatus of the present invention uses a series of bins for the introduction of the materials to be molten on the molds, which are controlled by a computerized control panel.

Simulated tissue structures for practicing surgical techniques and methods of manufacturing those structures are provided. In particular, a realistic organ model or simulated tissue portion for practicing the removal of a tumor or other undesired tissue followed by suturing a remnant defect as part of the same surgical procedure is provided. The simulated tissue structures include a polyp simulation having a suturable mesh layer that is separable from a defect layer. A simulated colon model with interchangeable and suturable tissue pods is also provided as is a fully suturable rectum model and a rectum model with integrative suturable and removable polyp zones.