A method of depositing an extrudable substance comprises, with a cartridge positioned inside a sleeve between an inner tubular sleeve wall and an outer tubular sleeve wall, circumscribing the inner tubular sleeve wall, and also positioned between a twist-lock pressure cap, hermetically coupled with the cartridge, and a valve, communicatively coupled with the cartridge, linearly moving an annular plunger, received between an inner tubular cartridge wall and an outer tubular cartridge wall, circumscribing the inner tubular cartridge wall, toward the valve along a first axis to urge the extrudable substance from the cartridge, through the valve, and out of a nozzle that is communicatively coupled with the valve. The method also comprises controlling flow of the extrudable substance from the valve to the nozzle.

A method of depositing an extrudable substance onto a surface comprises (1) with a cartridge positioned inside a sleeve between an inner tubular sleeve wall and an outer tubular sleeve wall, circumscribing the inner tubular sleeve wall, and also positioned between a push-lock pressure cap, hermetically coupled with the cartridge, and a valve, communicatively coupled with the cartridge, linearly moving an annular plunger, received between an inner tubular cartridge wall and an outer tubular cartridge wall, circumscribing the inner tubular cartridge wall, toward the valve along a first axis to urge the extrudable substance from the cartridge, through the valve, and out of a nozzle that is communicatively coupled with the valve; and (2) controlling flow of the extrudable substance from the valve to the nozzle.

A fluid-flow-modification plate comprises a monolithic body, having an inlet-side surface, an outlet-side surface, a first passage, a second passage, a third passage, and a fourth passage. The first passage, second passage, third passage, and fourth passage each extend between the inlet-side surface and the outlet-side surface. The first passage and second passage intersect each other at a first intersection boundary. The third passage and fourth passage intersect each other at a second intersection boundary. The first passage and third passage do not intersect each other. The first passage and fourth passage do not intersect each other. The second passage and third passage do not intersect each other. The second passage and fourth passage do not intersect each other. The first-passage-inlet-opening perimeter boundary has single-point contact with the fourth-passage-inlet-opening perimeter boundary. The second-passage-outlet-opening perimeter boundary has single-point contact with the third-passage-outlet-opening perimeter boundary.

A fluid-flow-modification plate comprises a monolithic body, having an inlet-side surface and an outlet-side surface, a first passage, a second passage, a third passage, and a fourth passage. The first passage, the second passage, the third passage, and the fourth passage each extend between the inlet-side surface and the outlet-side surface. The first passage and the second passage intersect each other at a first intersection boundary. The third passage and the fourth passage intersect each other at a second intersection boundary. The first passage and the third passage do not intersect each other. The second passage and the fourth passage do not intersect each other. The first-passage-inlet-opening perimeter boundary has only two points of intersection with the fourth-passage-inlet-opening perimeter boundary. The second-passage-outlet-opening perimeter boundary has only two points of intersection with the third-passage-outlet-opening perimeter boundary.

A nozzle arrangement for a granulator has a nozzle body with an inlet side as well as an outlet side, a nozzle plate with nozzle holes arranged on the outlet side for forming melt strands, and flow channels formed in the nozzle body and connected to the inlet side and the outlet side in a fluid-conducting manner for supplying a melt flow to a nozzle plate. An annular connection channel connects a plurality of flow channels in a fluid-conducting manner. A method for separating a melt flow into melt strands is also described.

A method and a device for manufacturing a rubber coated cord, comprising:

a rubber coated cord including a preceding cord is manufactured by causing the preceding cord to pass through a preceding head while filling the preceding head with unvulcanized rubber extruded from a rubber extruder, and a rubber coated cord including a next cord is manufactured by setting a leading edge portion of the next cord in a state where the leading edge portion of the next cord has passed through the next head in advance, manufacturing a predetermined length of the rubber coated cord including the preceding cord, and subsequently causing the next cord including a leading edge portion side range bonded to a trailing edge portion of the rubber coated cord including the preceding cord to pass through the next head while switching from the preceding head to the next head.

A fluid-flow-modification plate comprises a monolithic body, having an inlet-side surface, an outlet-side surface, a first passage, a second passage, a third passage, and a fourth passage. The first passage, second passage, third passage, and fourth passage each extend between the inlet-side surface and the outlet-side surface. The first passage and second passage intersect each other at a first intersection boundary. The third passage and fourth passage intersect each other at a second intersection boundary. The first passage and third passage do not intersect each other. The first passage and fourth passage do not intersect each other. The second passage and third passage do not intersect each other. The second passage and fourth passage do not intersect each other. The first-passage-inlet-opening perimeter boundary has single-point contact with the fourth-passage-inlet-opening perimeter boundary. The second-passage-outlet-opening perimeter boundary has single-point contact with the third-passage-outlet-opening perimeter boundary.

Recently, we have introduced 3D-micro-patterned pharmaceutical dosage forms for enhancing the efficacy, safety, convenience, and cost-effectiveness of drug therapies. Presented herein are an apparatus and a method for the manufacture of such dosage forms. The apparatus comprises at least a first extruder and at least a second extruder. The first extruder comprises an extruder channel having an exit port with a valve mated to an input port of a second extruder. Said second extruder comprises a translatable piston for extruding plasticized fiber at controlled speed. The apparatus further comprises a stage movable at the controlled speed of the extruded fiber for depositing said fiber to a three dimensional structural framework. The method includes extruding plasticized matrix from a first extruder into a second extruder, extruding said plasticized matrix from the second extruder through a fiber fabrication exit port at controlled speed to form extruded fiber, and depositing said extruded fiber onto a fiber assembling stage to form a three dimensional structural framework.

A fluid-flow-modification plate (200) comprises a monolithic body (300), having an inlet-side surface (301) and an outlet-side surface (302), a first passage (501), a second passage (502), a third passage (503), and a fourth passage (504). The first passage (501), the second passage (502), the third passage (503), and the fourth passage (504) each extend between the inlet-side surface (301) and the outlet-side surface (302). The first passage (501) and the second passage (502) intersect each other at a first intersection boundary (530). The third passage (503) and the fourth passage (504) intersect each other at a second intersection boundary (531). The first passage (501) and the third passage (503) do not intersect each other. The second passage (502) and the fourth passage (504) do not intersect each other. The first-passage-inlet-opening perimeter boundary (311) has only two points of intersection with the fourth-passage-inlet-opening perimeter boundary (314). The second-passage-outlet-opening perimeter boundary (412) has only two points of intersection with the third-passage-outlet-opening perimeter boundary (413).

The extrusion installation is configured for manufacturing a complex profiled-element strip, such as a tread, based on elastomer compounds by co-extrusion, and comprises multiple extruders feeding elastomer compounds to an extrusion head. The extrusion head receives a proportion of elastomer compound of between 2 and 25% of the total volumetric throughput of the installation from at least one Archimedean-screw extruder and the rest from positive-displacement extruders.