Method for processing hot-filled plastic containers are provided. In some embodiments, the method may include hot-filling a plastic container, sealing the container, and conveying the sealed container, each with an inner annular wall and a push-up portion in a first position. In some embodiments, the method may further include creating a vacuum pressure in the hot-filled and sealed container and repositioning or inverting the push-up portion from the first position to a second position under the vacuum pressure.

Method for processing hot-filled plastic containers are provided. In some embodiments, the method may include hot-filling a plastic container, sealing the container, and conveying the sealed container, each with an inner annular wall and a push-up portion in a first position. In some embodiments, the method may further include creating a vacuum pressure in the hot-filled and sealed container and repositioning the push-up portion from the first position to a second position under a mechanical force.

A method for producing a sterilized container comprises: providing a preform having a hanger arranged on a bottom of the preform, heating the preform in a heating device, feeding the heated preform into a stretching and blowing apparatus, stretching and blowing the preform in the stretching and blowing apparatus such that the container for the infusion solution is formed from the preform, cleaning the formed container in a rinsing apparatus, and drying the cleaned container in a drying device, filling the cleaned and dried container at least with an infusion solution, via a filling opening present in the container, in a filling plant, closing the container by attaching a closure cap to the filling opening of the container, sterilizing the closed container in an autoclave, wherein the hanger of the preform is oriented and folded over by a bending apparatus prior to stretching and blowing in the stretching and blowing apparatus.

A plastic container includes a hollow body portion including a lower supporting base portion; a sidewall portion extending upwardly from the base portion; and a neck portion extending upwardly from the sidewall portion. The neck portion includes a support flange having an upper and lower surface, at least one thread, and a dispensing opening at the top of the neck portion. In embodiments, a closure may be provided to form an assembly. A preform and method for making a container are also disclosed.

A plurality of containers fabricated from plastic preforms, wherein the form of each of the containers is partially defined, through expansion of the containers by other containers adjacent thereto. A package including a plurality of the plastic containers is also provided.

A blow molding apparatus is provided with a mold carriage movable in a path between an extruder station and a blow-and-fill station. The mold carriage can have one or more mold assemblies. Each mold assembly has opposed first and second mold halves that together define a mold cavity. The first mold half is fixed to the mold carriage while the second mold half is independently movable relative to the first mold half within the mold carriage to open and close the mold assembly.

A method of controlling a temperature of a biopharmaceutical product during blow-fill sealing, includes developing a model based on heat transfer mechanisms that incorporates the effects of the blow-fill sealing on the biopharmaceutical product, providing a parison to a blow-fill sealing machine for accepting the biopharmaceutical product during the blow-fill sealing, predicting a temperature of at least one the biopharmaceutical product, the parison, and a component of the blow-fill sealing machine at a stage in the blow-fill sealing, and adjusting a parameter of the blow-fill sealing machine to reduce damage to the biopharmaceutical product.

An apparatus for producing plastic bottles includes a molding machine to receive and mold the preforms into bottles; a labeling machine to label the bottles; a filler to fill the bottles; a packer to package the bottles; and a distributor arranged at an outfeed of the labeling machine or the filler to transfer the bottles to the packer. No buffers are positioned between at least one of the molding machine, the labeling machine, and the filler and at least one of the packer and the distributor to bloc-synchronize the at least one of the molding machine, the labeling machine, and the filler with the at least one of the packer and the distributer. The at least one of the molding machine, the labeling machine, and the filler being spaced a distance from the at least one of the packer and the distributor via one or more transfer starwheels.

A method of sterilizing a bottle includes steps of: sterilizing bacteria adhering to a preform (1) made of resin by gasifying a sterilizer, discharging a sterilized gas (G) from a nozzle (6) toward a preform, now traveling, so as to adhere to the preform (1); activating the sterilizer adhering to the preform by blasting hot air (P) to the preform; sterilizing the bacteria adhering to the preform, and removing the sterilizer adhering to the preform (1); heating the preform to a temperature suitable for blow-molding treatment; and blow-molding the preform within a mold (4) to mold the preform into a bottle (2), wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.

A synchronization system for a container-processing plant, including a container-forming machine configured to form a container, the container-forming machine having a first rotating wheel for rotating the container about a first rotation axis; a container-filling machine operatively coupled to the container-forming machine and configured to fill the container, the container-filling machine having a second rotating wheel for rotating the container about a second rotation axis; and at least one electric motor configured to cause the first rotating wheel and the second rotating wheel to rotate, the synchronization system comprising: a position sensor provided in the container-forming machine and configured to detect a rotating position of the first rotating wheel and to generate a position detection signal; at least one control unit configured to: receive information associated with the position detection signal; synchronize the rotation of the second rotating wheel to the rotation of the first rotating wheel based on the information associated with the position detection signal; and synchronize the rotation of the container-forming machine and container-filling machine from a zero speed up to a full operating speed of the container forming machine at which processing operations are designed to be performed.