A method and apparatus for sealing films. In one embodiment the sealing device comprises a horn and an anvil. The film has a standard portion and an increased portion. Increased energy is applied to the film in the increased portion compared to the energy applied to the standard portion. Such a method allows for sealing of varying number of layers.

A cell culture device comprises a cell culture membrane and a substrate fixed to the cell culture membrane. The cell culture membrane is made from a thermosetting resin and has a plurality of pores that are open to at least one surface including a surface on a side that is in contact with the substrate. The substrate is made from a thermoplastic resin. In a contact region between the cell culture membrane and the substrate, part of the substrate is extended to form bulges in the pores of the cell culture membrane that are open in the contact region. This configuration suppresses reduction of the strength of the cell culture membrane and reduction of the flatness of the cell culture membrane (membrane accuracy) in the cell culture device in which the cell culture membrane and the substrate are fixed to each other.

A structural element for use as a core layer in a sandwich composite element, wherein the structural element (2) is formed from a plurality of mutually welded body segments (4, 5) made from an extrusion foamed thermoplastic, and wherein the structural element (2) has a first face side (1) for bonding to a cover layer, wherein a surface of the first face side (1) that can be loaded with a resin (8) has open pores (6), wherein the surface of the first face side (1) is created by hot-element cutting, in such a manner that the surface is thermally sealed to some extent, wherein a gloss value of the surface of the first face side (1), measured at 60 in accordance with DIN 67530-1982 is between 2 and 10 gloss units.

A method of producing flexible polypropylene fabric bags with heat fused seams comprising providing fabric pieces, wherein each fabric piece has a coated side and an uncoated side; positioning fabric pieces so that a coated side of one fabric piece faces a coated side of another fabric piece; selecting an area of fabric to be joined for forming a seam or joint; applying heat to the area to be joined that is less than the melting point of the fabrics, for forming one or more seams or joints and wherein the heat fused seams or joints of a resulting polypropylene bag retains at least 85% of the fabric strength without using sewing machines.

A fluidic device including an inorganic solid support attached to an organic solid support by a bonding layer, wherein the inorganic solid support has a rigid structure and wherein the bonding layer includes a material that absorbs radiation at a wavelength that is transmitted by the inorganic solid support or the organic solid support; and a channel formed by the inorganic solid support and the organic solid support, wherein the bonding layer that attaches the inorganic solid support to the organic solid support provides a seal against liquid flow. Methods for making fluidic devices, such as this, are also provided.