Provided is a tube joining device that allows a user to easily and appropriately perform setting of tubes which become a joining target, and is capable of preventing occurrence of a joining failure caused by a setting error of the tubes in advance. A tube joining device 1 includes: a first tube holding portion 41 that is capable of holding a first tube T1; a second tube holding portion 42 that is disposed in adjacent to the first tube holding portion, and is capable of holding a second tube T2 at a position that is parallel to the first tube; and a housing 2 that is provided with a cover member 20 that is closed to cover fusion-joining sites C of the first tube and the second tube. The cover member is slidable along a direction in which the first tube and the second tube are disposed in parallel.

A sterile container including at least one hollow fiber filter module, especially dialyzer, which is accommodated in a hermetically sealed holding volume of a primary package and includes a blood compartment delimited by a blood inlet opening and a blood outlet opening, wherein a plurality of hollow fiber filter modules is arranged in the primary package and the sterile barrier of the blood compartment of each hollow fiber filter module inside the primary package is implemented by caps which close the blood inlet opening and the blood outlet opening of each hollow fiber filter module. A method of manufacturing such sterile container is also disclosed.

[Object] Provided is a tube joining device that allows a user to easily and appropriately perform setting of tubes which become a joining target, and is capable of preventing occurrence of a joining failure caused by a setting error of the tubes in advance.

[Solving Means] A tube joining device 1 includes: a first tube holding portion 41 that is capable of holding a first tube T1; a second tube holding portion 42 that is disposed in adjacent to the first tube holding portion, and is capable of holding a second tube T2 at a position that is parallel to the first tube; and a housing 2 that is provided with a cover member 20 that is closed to cover fusing-joining sites C of the first tube and the second tube. The cover member is slidable along a direction in which the first tube and the second tube are disposed in parallel.

Provided is a tube joining apparatus that allows a user to easily and properly set tubes to be joined, and can prevent occurrence of joining failures due to tube setting errors.

A tube joining apparatus 1 includes a housing, a lid relatively movable toward and away from the housing, a tube holding part that holds a first tube and a second tube individually in a state of being placed side by side in an oblique direction with respect to a height direction of the housing, and a tube pressing part that presses the first tube and the second tube against each other as the lid relatively moves toward the housing.

A method is described for opening a heat bonded sterile connection that includes a skin of material blocking flow between the connection site. The method includes applying external pressure to the connection site.

A method is described for opening a heat bonded sterile connection that includes a skin of material blocking flow between the connection site. The method includes applying external pressure to the connection site.

[Object] To provide a tube joining device in which the degree of freedom of device design is improved.

[Solving Means] A tube joining device 1 includes a delivery mechanism 500. The delivery mechanism includes a first pusher member 542 that is provided to perform forward movement and backward movement along a delivery direction and delivers a wafer WF to a first position PS2 that is set between a take-out position PS1 at which the wafer WF is taken out from a cassette WC and a stand-by position PS3, and a second pusher member 543 that is provided to perform forward movement and backward movement along the delivery direction in combination with the first pusher member, and delivers the wafer from the first position to the stand-by position. An operation of delivering the wafer by the first pusher member is capable of being switched to an operation of delivering the wafer by the second pusher member in synchronization with forward movement and backward movement of the first pusher member and the second pusher member.

[Object] Provided is a tube joining device which is capable of preventing occurrence of a joining failure caused by a setting error of tubes in advance, and in which tube holding and release of the holding are realized by a simple device configuration.

[Solving Means] A tube joining device 1 includes: a first tube holding portion 160 that is capable of holding a first tube T1; a second tube holding portion 230 that is capable of holding a second tube T2; a tube superimposing portion 30 that disposes the first tube and the second tube in a superimposed manner; and a switching mechanism 240 that is capable of switching holding of the second tube by the second tube holding portion and release of the holding. The switching mechanism applies a biasing force for maintaining a state in which the second tube is held to the second tube holding portion, and applies a biasing force for maintaining a state in which the holding of the second tube is released to the second tube holding portion in accordance with relative approaching of the tube holding portions.

A method is described for opening a heat bonded sterile connection that includes a skin of material blocking flow between the connection site. The method includes applying external pressure to the connection site.

A tube seal apparatus including a sealing iron having a tube sealing end, an insulating shroud having a tube clamping end, wherein the sealing iron is at least partially disposed within the insulating shroud. The apparatus further includes an anvil having a cutting detail and a non-stick membrane disposed between the anvil and the tube clamping end of the insulating shroud. The sealing iron and insulating shroud are configured to advance towards a tube to be sealed positioned between the non-stick membrane and the anvil. The tube clamping end is configured to clamp the tube through the non-stick membrane. The sealing iron is configured to advance towards the tube to melt and seal the tube against the cutting detail through the non-stick membrane.