Systems and methods are disclosed that include an operation chamber, a plasma generator having at least one plasma head disposed within the operation chamber and in proximity to a profile formed by cutting a piece of tubing, and a mechanical motion module. The plasma generator generates a plasma treatment and applies the plasma treatment via the at least one plasma head to the profile to activate material on an end surface of the profile, within a lumen of the profile, or a combination thereof. Once the material of the profile is activated by the plasma treatment, the mechanical motion module manipulates the profile to close the lumen of the profile to aseptically seal the profile.

An integrated system for fusing and sealing of a plurality of tubes is disclosed. The integrated system includes one or more fusing units configured to cut one or more tubes of multiple tubes simultaneously, and fusing the one or more tubes together along their respective cut ends; one or more sealing units configured to seal an end of the tube of the multiple tubes; and a control unit for controlling functions of the one or more fusing units and the one or more sealing units.

A tube seal apparatus including a sealing iron having a tube sealing end, an insulating shroud having a tube clamping end, wherein the sealing iron is at least partially disposed within the insulating shroud. The apparatus further includes an anvil having a cutting detail and a non-stick membrane disposed between the anvil and the tube clamping end of the insulating shroud. The sealing iron and insulating shroud are configured to advance towards a tube to be sealed positioned between the non-stick membrane and the anvil. The tube clamping end is configured to clamp the tube through the non-stick membrane. The sealing iron is configured to advance towards the tube to melt and seal the tube against the cutting detail through the non-stick membrane.

A blood bag sterile connection method includes the following steps: 1) placing blood bag tubes above the wire box, clamping positions to be cut by using the vascular clamps, and simultaneously moving the two vascular clamps in opposite directions; 2) heating the composite metal wire, and cutting the blood bag tubes by using the composite metal wire; 3) after cutting the blood bag tubes, aligning the blood bag tubes to be connected; 4) moving the two vascular clamps towards each other, rolling away the used composite metal wire, and rolling out a new composite metal wire; 5) connecting the blood bag tubes by heating the composite metal wire, and simultaneously moving the two vascular clamps towards each other; and 6) returning the wire box to the initial position, taking out the connected blood bag tubes, and returning the vascular clamps to the initial positions.

A welding device for the sealing welding of thermopolastic hoses (184), includes a clamping device (12) with at least two clamping jaws (122, 124), of which at least one is movable and between which a hose (184) which is to be welded can be clamped, wherein the clamping device (12) has a heating devices (38; 40; 64) which is coupled to a control unit (30) and is configured to heat the hose clamped between the clamping jaws (122, 124). The invention is distinguished in that the at least one movable clamping jaw (122) is actuable with a controllable, bidirectional actuator (32, 34; 42-52; 54, 56, 58) which is coupled to the control unit (30) in such a manner that the clamping pressure acting on the hose (184) can be adjusted independently of the heating device.

Delivering a blood processing solution to blood in a blood bag includes coupling a first tube to a vented spike at one end and to a Y-shaped tube connector at a second end. An in-line microbiotic barrier filter is coupled to the first tube between its ends. A second tube is coupled to a transfer bag at one end and to the Y-shaped tube connector at its other end. A third tube is coupled to the output of the Y-shaped tube connector and sealed at its distal end. The blood bag includes a fourth tube that is sealed at a distal end. The third tube is welded to the fourth tube using a sterile tubing welder, wherein a functionally-closed, sterile flow path through which the blood processing solution can flow into the blood bag is maintained.

System, apparatus and method for opening a heat-bonded connection formed between two hollow, flexible thermoplastic conduits. A pressure difference is created between the inside of at least one of the conduits and the ambient atmosphere sufficient to cause expansion of a wall of the tubing conduit in the vicinity of a frangible portion at least partially blocking the connection to disrupt the frangible portion and reduce the blocking.

A method for producing sterile solution product bags includes positioning a manifold assembly onto a filling machine. The manifold assembly includes a plurality of bags, a first filter, and a connection line in fluid communication with the first filter. Each of the plurality of bags includes a bladder and a stem in fluid communication with the bladder and with the connection line. The method includes activating a pump and at least partially filling one or more of the bladders by pumping fluid through the feed line, the first filter, and the connection line. The method includes sealing the stem of each of the filled product bags at a location between the connection line and the bladder, thereby creating one or more at least partially filled and sealed product bags. The method includes separating each of the at least partially filled and sealed product bags from the connection line.

A tool is provided in a kit of parts for an implantable penile prosthesis that includes a first tubing section and a first connector that is attachable to a second tubing section and a second connector. The tool has a vertex end and an open end, a first arm extending from the vertex end to a first distal end, and a second arm extending from the vertex end to a second distal end. The first distal end is spaced apart from the second distal end to define the open end of the tool.