Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material. The lens body can be secured to the mask. The mask material can include a modulus of elasticity that is greater than or equal to a modulus of elasticity of the lens material.

A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.

A contact lens incorporating one or more surface modified zones on the anterior surface of the lens may be utilized to generate a friction driven rotational force when the upper and/or lower eyelids pass over the one or more regions during blinking. A small difference in the coefficient of friction between the modified and unmodified regions of the lens may result in an equivalent rotational force to that of a thickness gradient lens. This small difference in the coefficient of friction produces a means to orient and stabilize the contact lens on eye.

A mold for a front curve of an ophthalmic lens includes an inner region having a non-rotationally symmetric shape, an outer region having a rotationally symmetric shape, and a continuous middle region between the inner region and the outer region. A first portion of the middle region is in contact with the inner region, defining a non-rotationally symmetric rim or edge of a front surface of the ophthalmic lens. A second portion of the middle region is in contact with the outer region and is rotationally symmetrical.

The present invention relates to copolymers made from a polymerization mixture comprising (a) one or more polymerizable monomers, which monomers are characterized as having at least one vinylic group and not containing an amino acid residue, (b) one or more not-functionalized side chain-linked amino acids, (c) one or more functionalized side chain-linked amino acids, (d) a free radical initiator and, optionally, (e) a chain-transfer-agent. It also relates to block copolymers comprising the same monomers. The invention also encompasses silicone hydrogel contact lenses coated with or comprising the latter copolymers and block copolymers as well methods for introducing the copolymers and block copolymers into silicone hydrogel contact lenses.

A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.

A contact lens incorporating one or more surface modified zones on the anterior surface of the lens may be utilized to generate a friction driven rotational force when the upper and/or lower eyelids pass over the one or more regions during blinking. A small difference in the coefficient of friction between the modified and unmodified regions of the lens may result in an equivalent rotational force to that of a thickness gradient lens. This small difference in the coefficient of friction produces a means to orient and stabilize the contact lens on eye.

A method of making a contact lens includes providing a cylindrical blank for the contact lens, the cylindrical blank including a first portion and a second portion. The first portion is formed from a homogenous, optically clear material and the second portion is formed from an inhomogeneous, optically-scattering material. The method includes shaping the cylindrical blank to provide the contact lens. The contact lens includes a first region surrounded by a second region, the first region being formed from the homogenous, optically clear material and the second region being formed from the inhomogeneous, optically-scattering material.

A device comprises a surface that is a hydrogel having a targeted mesh size that permits a low-speed friction coefficient near or lower that that typically reported for cartilage of 0.01 to 0.02, a transition. The device can be a contact lens to sit on the cornea where, during a blink, eyelid slides past the eye surface at about 100 mm s.sup.1. The hydrodynamic lubrication of the hydrogel of the device separates the contact lens surface from the surfaces of the tarsal conjunctiva and marginal conjunctiva of the eyelid. Other devices that can comprise the hydrogel of a targeted mesh size are those that can contact cartilage of articulating joints.

A contact lens incorporating one or more dynamic stabilization zones fabricated from a material that is readily deformable under eyelid pressure during blinking allows for the control over rotation of the contact lens on the eye. As the material deforms, the angle of contact between the eyelid and the one or more dynamic stabilization zones changes as does the rotational force acting on the contact lens.