The present invention generally relates to a method for producing inherently wettable silicone hydrogel contact lenses with a robusteness of lens shape and having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus.

The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.

A silicone elastomer-hydrogel hybrid contact lens includes a silicone elastomer layer and a hydrogel layer adhered to the silicone elastomer layer by a delamination-resistant bond that is formed by an elastomer-swellable monomer that is included in the polymerizable composition used to form the hydrogel layer.

A silicone elastomer-silicone hydrogel hybrid contact lens comprises a silicone elastomer layer adhered to silicone hydrogel layer by a delamination-resistant bond. The silicone hydrogel layer has a percent swell of about 5% up to about 20%. The silicone elastomer layer may have one or more objects embedded within it or adhered to its surface. Such objects may include variable-focus lenses and/or electronic components.

The disclosure describes an electrowetting contact lens comprising including an electrowetting cell. The cell includes first and second optical windows that form a sealed enclosure. A first electrode is formed on the first optical window, and a second electrode is formed on the second optical window. The first and second electrodes include an electrically conductive layer, and the first electrode includes at least one dielectric layer sandwiched between the relevant optical window and the at least one dielectric layer. Oil and saline layers are positioned in the sealed enclosure so that the oil is in contact with one electrode and the saline is in contact with the other electrode. A protective coating encloses the electrowetting cell, and a contact lens material encloses the sealing material. Other embodiments are disclosed and claimed.

A composition is provided for manufacturing contact lenses including a siloxane macromer represented by the following formula (I): ##STR00001##
wherein R1, R2 and R3 are independently C1-C4 alkyl groups, R4 is C1-C6 alkyl group, R5 is a residue obtained by removing NCO group from an aliphatic or aromatic diisocyanate, R6 and R7 are independently alkylene groups, and n is an integer of about 4-80, m is an integer of about 3-40; a crosslinking agent or a siloxane macromer represented by the following formula (II), wherein p is an integer of 4-80 and q is an integer of 3-40: ##STR00002##
and an initiator.

Methods for manufacturing contact lenses are provided. In an embodiment, the method includes mixing a siloxane macromer represented by the following formula (I), a hydrophilic monomer, a crosslinking agent or a siloxane macromer represented by the following formula (II), and an initiator to form a mixture. Then the mixture is injected into a mold of contact lens and heated to form contact lenses. The formula (I) and the formula (II) are shown respectively as the following: ##STR00001##
wherein R1, R2 and R3 are independently C1-C4 alkyl groups, R4 is C1-C6 alkyl group, R5 is a residue obtained by removing NCO group from an aliphatic or aromatic diisocyanate, R6 and R7 are independently alkylene groups, and n is an integer of 4-80, m is an integer of 3-40. ##STR00002##
wherein p is an integer of 4-80 and q is an integer of 3-40.

The invention is to provide an ophthalmic lens and manufacturing method thereof. The ophthalmic lens comprises a lens body, a polydopamine layer formed on a surface of the lens body and a first cellulose nanofiber (CNF) layer bonded to the polydopamine layer.

The invention is to provide an ophthalmic lens comprising a lens body, a polydopamine layer formed on the surface of the lens body and an antimicrobial layer bonded to the polydopamine layer, and manufacturing method thereof, wherein the antimicrobial layer is formed from a copolymer of carboxyl-containing polymer and zwitterionic polymer and a crosslinking agent, and the zwitterionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer and mixed-charge polymer or a combination thereof.

Described herein is a method for producing a contact lens comprising a central photochromic zone that has a diameter of about 13 mm or less and is concentric with the central axis of the contact lens. The method comprises: applying a first polymerizable fluid composition containing at least one photochromic compound on a central portion of the molding surface of a female mold half to form a circular layer; partially photocuring, in situ, the circular layer in the female mold half by using a visible light; dispensing a second polymerizable fluid composition over the partially-cured circular layer on the molding surface of the female mold half; and a step of thermally curing the second polymerizable fluid composition and the partially-cured circular layer immersed therein in the mold cavity formed between the molding surfaces of the female mold half and a male mold half.