An example method of forming a biodegradable component includes extruding a mixture of biodegradable material and water through a die. The method further includes dividing the extruded mixture to form a plurality of biodegradable pellets. The method further includes forming the plurality of biodegradable pellets into a component. The water acts as a binding agent to bind the plurality of biodegradable pellets to one another.

A method for producing bone grafts using 3-D printing is employed using a 3-D image of a graft location to produce a 3-D model of the graft. This is printed using a 3-D printer and a printing medium that produces a porous, biocompatible, biodegradable material that is conducive to osteoinduction. For example, the printing medium may be PCL, PLLA, PGLA, or another approved biocompatible polymer. In addition such a method may be useful for cosmetic surgeries, reconstructive surgeries, and various techniques required by such procedures. Once the graft is placed, natural bone gradually replaces the graft.

An object of the present invention is to provide a method for producing a polymeric molded product, which does not undergo a considerable molecular weight reduction during melt-molding, even in a polymer may easily lose its molecular weight when it is in a melted state. The present invention provides a method for producing a polymeric molded product, which comprises melt-molding a polymer comprising lamellar crystals that are different in lamella thickness, in a temperature range where some of the lamellar crystals undergo melting and flowing, and the other balance lamellar crystals remain unmelted.

The present disclosure provides: a biodegradable nonwoven fabric for thermoforming, the biodegradable nonwoven fabric being composed of a fiber of a polylactic acid-based polymer, and having a basis weight of 20-300 g/m.sup.2, preferably, a biodegradable nonwoven fabric characterized by being composed of a long fiber of a polylactic acid polymer, having an MD-direction elongation of 50% or more at 120° C., and having an MD-direction dimensional change rate of ±4% or less at 80-140° C. as determined by thermomechanical analysis; a method for producing a molded body by using said biodegradable nonwoven fabric; and a method for molding a biodegradable beverage extraction container, the method being characterized in that the molded body has an MD-direction elongation change rate of 4% or less, as determined by thermomechanical analysis (TMA) under a load of 0.05 N/2 mm at 30-100° C.

An implantable, autonomously growing medical device is disclosed. The device may have an outer, braided outer element that holds an inner core. Degradation and/or softening of the inner core permits the outer element to elongate, allowing the device to grow with surrounding tissue. The growth profile of the medical device can be controlled by altering the shape/material/cure conditions of the inner core, as well as the geometry of the out element.

The disclosure relates to a subcutaneously implanted port device for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein may reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a tapered seat for receiving an access tube, the first tapered seat having a proximal portion, a distal portion, and a conical section extending between the proximal portion and the distal portion; and an interface surface configured to engage a blood vessel or a vascular access catheter. The proximal portion of the tapered seat is configured to receive the access tube therethrough, and the tapered seat creates a mismatch fit with a diameter of the access tube when in use for an increase in flow during treatment.

Provided is a method with which a biodegradable polyester film containing polyhydroxyalkanoate can be stably produced by film blowing under practical processing conditions. A method for producing a biodegradable polyester film containing a biodegradable aliphatic polyester (A) and a fatty acid amide (B) by film blowing, the biodegradable aliphatic polyester (A) containing polyhydroxyalkanoate, the method including: a step (I) of dry-blending the biodegradable aliphatic polyester (A) with a masterbatch containing the fatty acid amide (B) and a base material resin; and a step (II) of subjecting the mixture obtained in the step (I) to film blowing.

Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.

Provided are a biodegradable sheet with antiviral properties, a manufacturing method thereof, and the use thereof. The biodegradable sheet comprises: a biodegradable polymer resin consisting of a polylactic acid-based polymer; or a composite degradable polymer resin comprising of a biodegradable resin and a petrochemical resin; and particles of an inorganic antiviral agent or aggregated composite particles of at least two inorganic antiviral agents incorporated into the biodegradable sheet so that the inorganic antiviral agent can be dispersed with a particle size of 100 to 900 nm.

According to an example aspect of the present invention, there is provided means for maximizing the amount of cellulose content in 3D-printable bio-based thermoplastic materials and increasing temperature resistance compared to the existing bio-based thermoplastic materials used in additive manufacturing.