A water-soluble packaging film according to the present invention is a water-soluble packaging film comprising a polyvinyl alcohol resin, and has, on a film surface, irregularities having a surface roughness (Ra) of 0.3 to 1 m and a maximum height (Rz) of 3 to 9 m.

A process for manufacturing a water soluble product including the steps of: providing a water soluble fibrous first ply; providing a water soluble fibrous second ply formed on a surface other than the first ply, wherein the second ply is separate from the first ply; superposing the first ply and the second ply; and joining a first portion of the first ply to a second portion of the second ply to form the water soluble product.

The disclosed methods relate to forming microneedle arrays from a production mold that comprises a flexible mold material. The disclosed methods can be used to reproducibly manufacture undercut dissolvable and coated microneedle arrays with various shapes and structures.

Systems and methods in accordance with embodiments of the invention fabricate objects using investment molding techniques. In one embodiment, a method of fabricating an object includes: fabricating a subassembly including a plurality of volumes; where each volume is defined by the homogenous presence or absence of a material; where fabricating the subassembly includes using an additive manufacturing process; where at least one of the plurality of volumes defines a shape that is to exist in the object to be fabricated; where at least a first of the plurality of volumes includes a first dissolvable material; dissolving the first dissolvable material; where the dissolution of the first dissolvable material does not dissolve at least one other material within the subassembly; forming at least one cavity within the subassembly; and introducing an additive material into the at least one cavity.

Ophthalmic lens molds made from at least one vinyl alcohol copolymers with high amorphous content, ophthalmic lenses including silicone hydrogel contact lenses formed using these molds, packaged ophthalmic lenses present in a solution comprising the at least one vinyl alcohol copolymer with high amorphous content, and related methods are described. The methods of manufacturing ophthalmic lenses can use wet demolding, delensing or demolding and delensing processes involving dissolving the molds in water or an aqueous solution.

The present disclosure relates to a method and an apparatus for precipitating and collecting a support material dissolved in an aqueous solution after production of an additively manufactured part wherein a divalent metal is added to the aqueous solution to induce precipitation the support material.

Method for coating a product having a wall formed by at least a portion having at least partly a cell structure, preferably at least partly an open cell structure, wherein a foil or foil laminate is pressure formed over at least a part of at least one side of said wall, said foil or at least one layer of said laminate forming a coating of said part of the wall.

A method of manufacturing a composite material that is formed to include an aperture is provided. The method includes disposing a plurality of woven substances including reinforcement fibers on a jig having a protrusion to fit the woven substances on the protrusion and thus provide the aperture. Additionally, the method includes integrally mounting the jig and a plurality of the woven substances in a mold, and adding a resin to the mold to immerse the plurality of the woven substances with the resin.

Ophthalmic lens molds made from at least one vinyl alcohol copolymers with high amorphous content, ophthalmic lenses including silicone hydrogel contact lenses formed using these molds, packaged ophthalmic lenses present in a solution comprising the at least one vinyl alcohol copolymer with high amorphous content, and related methods are described. The methods of manufacturing ophthalmic lenses can use wet demolding, delensing or demolding and delensing processes involving dissolving the molds in water or an aqueous solution.

Described herein are sacrificial templates generated from water soluble thermoplastic-divalent cation-composite materials, such as poly(vinyl alcohol)-calcium. Also described herein are methods for the use of such sacrificial templates in casting of precise internal space microarchitectures within hydrogels, such as microchannel networks within alginate hydrogels.