The disclosed methods relate to forming microneedle arrays from a production mold that comprises a flexible mold material. The disclosed methods can be used to reproducibly manufacture undercut dissolvable and coated microneedle arrays with various shapes and structures.

Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a component present therein. Composite filaments suitable for additive manufacturing may comprise a continuous polymer phase of a first thermoplastic polymer and a second thermoplastic polymer that are immiscible with one another, and electrically conductive particles distributed in the continuous polymer phase, such as microparticles, nanoparticles, or any combination thereof. The first thermoplastic polymer is dissolvable or degradable and the second thermoplastic polymer is insoluble or non-degradable under specified conditions. Removal of the first thermoplastic polymer from a printed part may introduce porosity thereto, thereby inducing or enhancing piezoresistivity within the printed part. An aqueous mixture comprising the electrically conductive particles and the first and second thermoplastic polymers may have water removed therefrom, and the resulting composite residue may be extruded to form the composite filaments.

There is provided a water-soluble film containing polyvinyl alcohol resin, wherein a ratio RSm (LD/TD) is 1.2 or greater and 2.5 or less, where the RSm (LD/TD) is the ratio of an average length RSm (LD) of roughness curve elements on at least one film surface in the longitudinal direction to an average length RSm (TD) of roughness curve elements on the same film surface in the transverse direction. This allows provision of a water-soluble film that can be suitably used for manufacturing a package with excellent uniformity of seal strength, even for manufacturing a package with excellent uniformity of seal strength during high-speed sealing; and a package using the film.

The invention relates to a method of manufacturing a water-soluble sheet having an area of structured surface pattern, the structured surface pattern having one or more structural features having a measurement of less than 1000 m wherein the method comprises the steps of: a) providing a substrate having an area of complementary structured surface pattern; b) depositing a solution comprising a water-soluble polymer onto the substrate; and c) drying the solution to form a water-soluble sheet comprising an area of structured surface pattern.

Provided are a water-soluble film having excellent solubility in water and capable of reducing the stickiness of the contact surfaces to each other at the edges during storage in rolls, a production method thereof, and a package using the water-soluble film. A water-soluble film of the present invention includes a polyvinyl alcohol resin. The water-soluble film satisfies a formula (1) below when amounts of crystalline component are respectively (A1).sub.0, (A1).sub.60, and (A1).sub.180, the amounts being obtained from a spin-spin relaxation curve by .sup.1H pulse NMR measurement of the water-soluble film immediately after, 60 seconds after, and 180 seconds after the water-soluble film is immersed in a mixed solution of deuterated water and deuterated methanol mixed at a volume ratio of 1:1 at 5 C.

The invention relates to a water-soluble sheet comprising a nanostructured surface pattern having structural features of less than 2 m.

The invention is further related to a method of manufacturing such a water-soluble sheet having a nanostructured surface pattern having structural features of less than 2 m, wherein the method comprises contacting a water-soluble sheet with a substrate having a complementary nanostructured surface pattern.

Water-soluble unit dose article comprising a laundry or automatic dishwashing detergent and a method of making.

A continuous process for preparing a sheet article includes preparing a wet pre-mixture comprising a water-soluble polymer and a surfactant and having a viscosity of from 1,000 cps to 25,000 cps measured at 40 C. and 1 s.sup.1; aerating said wet pre-mixture to form an aerated wet pre-mixture having a density of from 0.05 to 0.5 g/ml; forming said aerated wet pre-mixture into a sheet having a top side and a bottom side; and drying said formed sheet of aerated wet pre-mixture on a conveying belt with the bottom side of said formed sheet contacting said conveying belt.

A method of forming dual layer water soluble packets includes drawing a base film into a cavity of a mold, drawing air through openings in the base film, metering an amount of a first product of a first color onto the base film in the cavity, metering an amount of a second product of a second color onto the amount of the first product, and, sealing a lid film to the base film.

The invention relates to a heating device (1) which is designed to heat a packaging film in a deep drawing process, over the course of which the heated packaging film is molded into the cavity of a deep drawing mold. The surface region of the heating device (1) which is brought into contact with the film section to be molded into the cavity has at least one depression (50), the opening area (40) of which equals 40 to 95% of the opening area (40) of the cavity. The invention also relates to a deep drawing device comprising the aforementioned heating device (1).