A sampling device adapted to cooperate with a sampling member subsequent to collection of a sample of animal tissue. The sampling device includes: a receiving tube designed for receiving the sample of animal tissue, containing at least one specific agent and comprising an inlet; a tube head removably attached to the inlet of the receiving tube and provided with a through channel ending in the receiving tube; a closing element configured to take at least two positions: a first position, in which the closing element is held into the tube head so as to plug the through channel of the tube head, and a second position, in which the closing element is released into the receiving tube.

It is disclosed a System for sampling tissue from an ear of an animal including: a male component (2) including a detachable sample collecting part (2b), comprising a cavity (2c) for collecting the sample and a cutting edge (2a) at an aperture of the cavity (2c) for cutting the sample from the animal ear; and a tissue sample container (3) including a container component (30) for receiving the sample collecting part (2b) and the tissue sampled, the container component (30) having an opening (30b) closed by a sealed membrane or a cover (30d). The tissue sample container (3) includes a ring (31) comprising a peripheral flange (31a), a protrusion (31b) and radial portions (31c), the radial portions (31c) supporting the protrusion (31b) in the middle of the peripheral flange (31a) of the ring (31); a moulded portion (32) around the peripheral edge (31a) of the ring (31) and the container component (30), to embed the ring (31) and the container component (30) above the sealed membrane or cover (30d), preventing detachment thereof, wherein the protrusion (31b) projects from the middle of the ring (31) in a direction opposite with respect to the container component (30) and wherein a length of the protrusion (31b) is equal to or minor than a depth of the cavity (2c) of the sample collecting part (2b) to enter entirely the cavity (2c) through the aperture thereof so as the cutting edge (2a) contacts the radial portions (31c) for cutting them at a predetermined portion (31cc) during use, when the sample collecting part (2b) is moved in a same axis along which the protrusion (31b) is arranged.