The present invention is directed to a process of manufacturing a pharmaceutical composition, a pharmaceutical composition produced by the process of the present invention and a container comprising a pharmaceutical composition produced by the process of the present invention.

A method for preparing food having at least a solid food component. The method comprises, during a high-temperature, short-time stage (HTST stage), cooking a surface of the solid food component at a temperature (HTST temperature) of greater than 140 C. The method further comprises placing the food into packaging to form a sterile food package containing the food. The method also comprises, during a low-temperature, long-time stage (LTLT stage), cooking the sterile food package at a temperature (LTLT temperature) of between 40 and 100 C.

A packaged coffee product with oxygen dissolved therein along with milk and/or sweeteners in the sealed packaging is provided. Preferably, the pH of the product is 4.6 or greater, preferably 5.0 or greater. The coffee product may be hot or cold brew coffee and may have other gasses such as nitrogen and/or carbon-dioxide in the sealed container. Ideally, there is oxygen in both the headspace and liquid portion of the beverage in order to inhibit C.Bot growth without requiring retort processing. Preferably, the calorie count is in the range of 0.5-9 calories per ounce.

A packaged coffee product with oxygen dissolved therein along with milk and/or sweeteners in the sealed packaging is provided. Preferably, the pH of the product is 4.6 or greater, preferably 5.0 or greater. The coffee product may be hot or cold brew coffee and may have other gasses such as nitrogen and/or carbon-dioxide in the sealed container. Ideally, there is oxygen in both the headspace and liquid portion of the beverage in order to inhibit C.Bot growth without requiring retort processing. Preferably, the calorie count is in the range of 0.5-9 calories per ounce.

A preform is sterilized by a preform sterilizer. The preform is blow-molded by a blow-molding device to manufacture a container. Next, the container is filled with a culture medium by a filling device without sterilizing the container by a container sterilizer, and the container is plugged by a plugging device. Thereafter, it is verified how much microorganism survive or propagate in the culture medium in the container. A degree of sterilization in the container sterilizer is adjusted on the basis of a verification result.

A filler assembly comprising a pouch preheat zone, a pouch sterilization zone, and a pouch flush zone. The preheat zone includes a preheat nozzle assembly having an inlet and an outlet, the outlet engageable with a pouch assembly, and a preheat vacuum nozzle assembly having an inlet engageable with a pouch assembly and an outlet attachable to a vacuum. The pouch sterilization zone includes a sterilization nozzle assembly having an inlet and an outlet, the outlet engageable with a pouch assembly, and, a sterilization vacuum nozzle assembly having an inlet engageable with a pouch assembly and an outlet attachable to a vacuum. The pouch flush zone includes a pouch flush nozzle assembly having an inlet and an outlet, the outlet engageable with a pouch assembly, and, a pouch flush vacuum nozzle assembly having an inlet engageable with a pouch assembly and an outlet attachable to a vacuum.

A sterilizing unit comprising at least one heater is provided, wherein said heater comprises a housing and at least one heating element extending in said housing for heating a flow of air being directed through the housing, and wherein said heating element is formed as a band of an electrically conductive material.

A sterilizing unit comprising at least one heater is provided, wherein said heater comprises a housing and at least one heating element extending in said housing for heating a flow of air being directed through the housing, and wherein said heating element is formed as a band of an electrically conductive material.

Induction heating systems for metal food cans configured to deliver sufficient heat into the can to sterilize the food within the can are provided. The heating system includes an induction coil and a control system. The control system is configured to monitor and control heating of sealed food cans during induction heating and to control and/or confirm various aspects of can heating during induction heating.

Induction heating systems for metal food cans configured to deliver sufficient heat into the can to sterilize the food within the can are provided. The heating system includes an induction coil and a control system. The control system is configured to monitor and control heating of sealed food cans during induction heating and to control and/or confirm various aspects of can heating during induction heating.