The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.

The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.

A method of sterilizing a preform includes steps of: sterilizing bacteria adhering to a preform (1) made of resin by gasifying a sterilizer, discharging a sterilized gas (G) from a nozzle (6) toward a preform (1), now traveling, so as to adhere to the preform (1); activating the sterilizer adhering to the preform (1) by blasting hot air (P) to the preform; and sterilizing bacteria adhering to the preform, and removing the sterilizer adhering to the preform (1), wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.

A method of sterilizing a preform includes steps of: sterilizing bacteria adhering to a preform (1) made of resin by gasifying a sterilizer, discharging a sterilized gas (G) from a nozzle (6) toward a preform (1), now traveling, so as to adhere to the preform (1); activating the sterilizer adhering to the preform (1) by blasting hot air (P) to the preform; and sterilizing bacteria adhering to the preform, and removing the sterilizer adhering to the preform (1), wherein the above steps are performed sequentially in order. According to the above-mentioned steps, the sterilizer does not enter a blow-molding machine.

A method for filling of a beverage packaging includes in-line microwave assisted pasteurizing a beverage, vaporized hydrogen peroxide treating a packaging, vaporized hydrogen peroxide treating a drinking straw, positioning the vaporized hydrogen peroxide treated drinking straw in the vaporized hydrogen peroxide treated packaging, fixing the drinking straw inside the packaging, adjusting a temperature of the pasteurized beverage and cold filling the pasteurized beverage into the packaging with the fixed straw, and sealing the packaging.

A method for filling of a beverage packaging includes in-line microwave assisted pasteurizing a beverage, vaporized hydrogen peroxide treating a packaging, vaporized hydrogen peroxide treating a drinking straw, positioning the vaporized hydrogen peroxide treated drinking straw in the vaporized hydrogen peroxide treated packaging, fixing the drinking straw inside the packaging, adjusting a temperature of the pasteurized beverage and cold filling the pasteurized beverage into the packaging with the fixed straw, and sealing the packaging.

A sealing arrangement is for a container (1) and/or container part, such as a closure cap placed onto the container (1). The interior of the container (1) is used to accommodate a medium, particularly a fluid bottled in a sterile manner, which can be removed from the container (1) by a removal device such as a syringe needle. The removal device penetrates sealing material (9) connected to the container. The sealing material (9) is fixedly connected to the outside (7) of the container (1) and/or container parts facing the environment by a fused and/or adhesively bonded connection.

A sealing arrangement is for a container (1) and/or container part, such as a closure cap placed onto the container (1). The interior of the container (1) is used to accommodate a medium, particularly a fluid bottled in a sterile manner, which can be removed from the container (1) by a removal device such as a syringe needle. The removal device penetrates sealing material (9) connected to the container. The sealing material (9) is fixedly connected to the outside (7) of the container (1) and/or container parts facing the environment by a fused and/or adhesively bonded connection.

A packaging system for the storage of an ophthalmic device is disclosed. The packaging system comprises a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising (a) one or more osmoprotectants, (b) one or more poloxamer comfort agents and (c) one or more polyol demulcents, wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is heat sterilized.

A packaging system for the storage of an ophthalmic device is disclosed. The packaging system comprises a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising (a) one or more osmoprotectants, (b) one or more poloxamer comfort agents and (c) one or more polyol demulcents, wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is heat sterilized.