The multi-chambered well dosage form and device disclosed herein can be single or multi dose capable for administration of pharmaceuticals of a range of particle sizes. The present dosage devices and systems provide for improved efficiency and patient ease of use owing to its compact size and simple design, low cost, and consistent, contamination free dosing of dry powder medicaments or other agents. The present disclosure provides a multi-chambered dosage form containing dry powder medical composition containing chamber well with an internal piercing device and one or more adjacent gas-filled chamber wells to aid the dispense of the powder contents to the user and in certain embodiments, without the requirement of an external energy sources common with active devices known in the art. Said methods, systems and devices provide increased ejection fraction and hence greater efficiency of drug delivery above that as provided by current devices.

The multi-chambered well dosage form and device disclosed herein can be single or multi dose capable for administration of pharmaceuticals of a range of particle sizes. The present dosage devices and systems provide for improved efficiency and patient ease of use owing to its compact size and simple design, low cost, and consistent, contamination free dosing of dry powder medicaments or other agents. The present disclosure provides a multi-chambered dosage form containing dry powder medical composition containing chamber well with an internal piercing device and one or more adjacent gas-filled chamber wells to aid the dispense of the powder contents to the user and in certain embodiments, without the requirement of an external energy sources common with active devices known in the art. Said methods, systems and devices provide increased ejection fraction and hence greater efficiency of drug delivery above that as provided by current devices.

A powder transfer bag includes a balloon or a membrane sealing its mouth. A connector to be used with the bags allows the bag to connect to a hydration device. A method of hydrating material in a powder transfer bag is provided.

A powder transfer bag includes a balloon or a membrane sealing its mouth. A connector to be used with the bags allows the bag to connect to a hydration device. A method of hydrating material in a powder transfer bag is provided.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A sealing container is designed to enable a user to adjust the timing of discharging the contents. The sealing container includes: a bag-shaped member for accommodating the contents therein, a sealing film for sealing the bag-shaped member, an opening means so configured that at least a part of which is movable toward the sealing film and is capable of opening the sealing film, an operation unit for performing an operation of moving the opening means, and a discharge means configured to be capable of discharging the contents from the bag-shaped member at a timing different from a timing at which the opening means penetrates the sealing film by operating the operation unit. It is possible for the user to perform only the operation of opening the sealing film by operating the operation unit, so that the user is able to arbitrarily adjust the timing at which the content is discharged from the bag-shaped member of the sealing container.

A flexible package for dispensing a liquid. The package includes a fitment and a piercing member. The fitment is secured to a wall of the flexible package and has a passageway extending through it and a screw-thread section. The piercing member has a passageway extending through it, a piercing tip, and a screw-thread section. The piercing member is configured for insertion in the passageway of the fitment, with the screw-thread sections engaging each other to cause the piercing tip to penetrate the package, whereupon the liquid within the package can flow into and through the piercing member.

A flexible package for dispensing a liquid. The package includes a fitment and a piercing member. The fitment is secured to a wall of the flexible package and has a passageway extending through it and a screw-thread section. The piercing member has a passageway extending through it, a piercing tip, and a screw-thread section. The piercing member is configured for insertion in the passageway of the fitment, with the screw-thread sections engaging each other to cause the piercing tip to penetrate the package, whereupon the liquid within the package can flow into and through the piercing member.