An environmental control assembly for controlling at least one environmental condition of one or more substances, the one or more substances being uncontained or contained within a substance container, the assembly comprising a first enclosure comprising a thermal insulator configured to provide a thermal shield to the substance, a second enclosure comprising at least one deformable environmental control material configured to regulate at least one environmental condition of the substance, wherein the second enclosure at least partially physically contacts with at least one of the substance and the substance container, and a housing at least partially comprising the first enclosure and the second enclosure.

An insulative packaging for the cold chain marketplace. The insulative packaging includes a base unit, a wall unit, and a top unit, which together form an enclosure. Each base unit, the wall unit, and the top unit have an inflatable liner, one or more insulative sheets, and a radiant barrier. The inflatable liner can be folded, and the one or more insulative sheets can be sandwiched between the two folds of the inflatable liner. An article to be protected can be placed within the enclosure, and insulative packaging can provide 360-degree insulation and protection.