A handheld reusable multi-compartmental mixing and dispensing container for storing fluids separately therein before mixing. The proportions of the substances in a mixture are externally adjustable. The desired concentration is determined by test components attached to the container that sense various environmental and user-specific factors. The amount of the adjustable substance to be added to a mixture is controlled by an adjustment wheel on the container. A single control button allows a user to choose what fluid substances are to be mixed and dispensed. A pressurized gas propellant in a replaceable canister moves the fluid around and out of the container.

The present invention provides an aerosol device for delivering a pharmaceutical formulation by inhalation via the mouth to the lungs or to the nostril in metered doses comprising: a pressurised aerosol canister including a vial containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further comprising a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a delivery outlet and a stem block, the stem block having a receptacle into which the valve stem of the metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice arranged to direct the pharmaceutical formulation through the delivery outlet, a transfer tunnel having an input opening and an output opening through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice, and a land length defining the distance from between the input opening and output opening, wherein the input opening and the output opening have cross-sectional areas of from 0.002 to 0.8 mm.sup.2 and the cross-sectional area of the input opening is smaller than the cross-sectional area of the output opening, and wherein the land length is from 0.5 mm to 10 mm.

The dosing device consists, for example, of a closure, having a closure body (1) with sealing closing means (7), which can be placed in a sealing manner on the connector. The metering means of the closure consist of just two components. There is first, seated securely in the closure body (1), a hollow cup (4) having, on the bottom side of the cup (4), a window (12) arranged in its side wall. The second component is a cap-shaped metering piston (10) having, on the upper side of the cap, a projection (5) which extends in the axial direction. This metering piston (10) with projection (5) fits into the cup (4), wherein its projection (5) covers and closes the window (12). The metering piston (10) is able to move axially in the cup (4) and its projection (5) is able to pivot to a limited degree toward the outer side of the window (12). In the pivoted-out state, it forms, together with the cup (4), an open valve which is otherwise closed.

An apparatus for delivering a predetermined quantity of content from a pressurized container includes a dispensing assembly which sits on the container and connects with an upper portion of a valve stem of the valve assembly, wherein the dispensing assembly includes a) an actuator cap having a discharge passage, which is open or obstructed and wherein the actuator cap acts as a metering chamber in combination with b) an adaptor which fits inside the cap and also snuggly engages the valve stem. The cap fits snuggly over the adjuster to define a metering chamber which depending on its position can close off the metered chamber or open it to the dispensing conduit nozzle. When the cap is depressed it pushes down on the adjuster which depresses the valve. The chamber fills, but nothing is released until the upstroke.

An apparatus for delivering a predetermined quantity of content from a pressurized container includes a dispensing assembly which sits on the container and connects with an upper portion of a valve stem of the valve assembly, wherein the dispensing assembly includes a) an actuator cap having a discharge passage, which is open or obstructed and wherein the actuator cap acts as a metering chamber in combination with b) an adaptor which fits inside the cap and also snuggly engages the valve stem. The cap fits snuggly over the adjuster to define a metering chamber which depending on its position can close off the metered chamber or open it to the dispensing conduit nozzle. When the cap is depressed it pushes down on the adjuster which depresses the valve. The chamber fills, but nothing is released until the upstroke.

A method and a system are described herein for preparing a custom cosmetic formulation. The system includes a controller in electronic communication with an order management system, wherein the order management system stores user-specific data including data related to a custom cosmetic formulation and components thereof, a plurality of valves for receiving pressurized fluid, the plurality of valves in electronic communication with the controller; a plurality of dispensers, each having a valve for metering fluid in predetermined quantities, and each having a dispensing head having a nozzle, each nozzle comprising a nozzle tip on a distal end thereof, wherein the nozzle tips are arranged so as to dispense a fluid into an inlet of a product receptacle, the dispensers in electronic communication with a data port; a measuring device in electronic communication with the controller, the measuring device capable of capturing data related to dispensed fluids from each of the plurality of dispensers and transmitting the data to the controller; a barcode scanner for reading order-specific instructions; a user interface for operator communication with the order management system and with the controller; a plurality of fluid conduits for introducing fluid to the dispensers; a fluid delivery apparatus for delivery of components of a custom cosmetic component to the dispensers; and a pressure source for pressurizing fluid in the fluid delivery apparatus for delivery of fluid from the fluid delivery apparatus to the plurality of dispensers.

Dispenser (1) for liquids comprising an applying nozzle constituted by a bell-shaped body (2) extending along a central axis (A) and provided, at the bottom, with an annular collar (3) and, at the top, with a convex cap (4); the bell-shaped body (2) having a first axial hole (5) whose cross-section decreases from the collar (3) towards said cap (4); a valve (7) for nebulizing the solution being housed inside the first hole (5) in a matching manner; an expansion device (9) being provided at the exit of said first hole (5).

A handheld reusable multi-compartmental mixing and dispensing container for storing fluids separately therein before mixing. The proportions of the substances in a mixture are externally adjustable. The desired concentration is determined by test components attached to the container that sense various environmental and user specific factors. The amount of the adjustable substance to be added to a mixture is controlled by an adjustment wheel on the container. A single control button allows a user to choose what fluid substances are to be mixed and dispensed. A pressurized gas propellant in a replaceable canister moves the fluid around and out of the container.

Provided is a cosmetics container. The cosmetics container (100) according to this embodiment includes a first container (120) configured to discharge a predetermined amount of cosmetics by a pressing motion, a second container (130) configured to discharge a predetermined amount of coolant by a pressing motion, a container (110) including the first container (120) and the second container (130) therein, a cooler (140), which includes a cooling pipe (141) connected to the first container (120) and allows the cosmetics to move therein and a cooling channel (143) formed to surround the cooling pipe (141) and connected to the second container (130) so that the coolant in the cooling channel (143) is evaporated while moving along an outer surface of the cooling pipe (141) to cool the cosmetics, and a pushing member (150) provided at one side of the container (110), wherein when the pushing member (150) is pressed to a predetermined depth (T), the coolant discharges from the second container (130) and moves to the cooling channel (143), and when the pushing member (150) is pressed over the predetermined depth (T), the cosmetics discharges from the first container (120) and moves to the cooling pipe (141), wherein the cooling pipe (141) and the cooling channel (143) extend on a plane perpendicular to a vertical direction of the container (110).

The replacement of chlorofluorohydrocarbon propellants in medical aerosols is of the utmost importance to the pharmaceutical industry. A number of formulations have been investigated. The present invention provides a medical aerosol formulation comprising a particular medicament, a fluorocarbon propellant and 6 to 25% w/w of the total formulation of a polar co-solvent, such formulation being substantially free of surfactant. Canisters suitable for delivering such a pharmaceutical formulation are also provided.