A flow modulation device 300 for controlling a rheological state of a dispensed pressurized fluid includes a porous element 304 and an exit tube. The porous element 304 is in fluid communication with a distal end of an outlet tube 303 and receives pressurized fluid in a first rheological state. The porous element 304 includes a plurality of channels that divide a flow channel into a plurality of flow paths through which the pressurized fluid flows and that modulates the flow of the pressurized fluid. The exit tube 305 includes proximal end 355 and distal end 345 and an intermediate body including a sidewall 365 defining a hollow internal lumen 375. The exit tube 305 is in fluid communication with the porous element 304 and receives the modulated pressurized fluid from the plurality of flow paths and refocuses the fluid to dispense the pressurized fluid in a second rheological state.

An adapter for a dispenser includes a longitudinal body with a first end that may be configured for connection with a dip tube and a second end that may be configured for connection with another object, such as a foam component. In embodiments, a cross piece is disposed between the first end and the second end. Further, in embodiments, one or more structures, such as barbs, may be provided between a cross piece and the second end.

An accessory device for delivering medications from press and breath metered-dose inhalers (pMDIs), including those medications containing hydrofluoroalkane propellants. The device includes a collapsible flexible bag to which is attached a bidirectional mouthpiece and an adaptor that receives the press and breath MDI. The mouthpiece contains a reed that functions as an audible signal, and a screen to prevent inhalation of unwanted particles. The adaptor positions the press and breath MDI at an angle to direct the aerosol spray toward the center of the collapsible flexible bag. When the press and breath MDI is triggered, it discharges the aerosolized medication into the center of the collapsible flexible bag which is then inhaled by the user through the mouthpiece. This collapses the bag. The reed emits an audible sound if the user inhales above a pre-determined flow rate to maximize medication delivery and ensure dose-to-dose consistency.

A refrigeration system includes a water circulation system and a replaceable water filter. The refrigerator includes a sensor that determines if a water filter is present, and a user interface that prompts a user to purge a water filter upon installation of a new water filter in the refrigerator. The water filter may include a memory storage device that stores information concerning the allowable life of the water filter, the remaining life of the water filter, and other information. Information concerning the remaining life of the water filter and other information can be displayed or otherwise communicated to a user by the user interface.

A refrigeration system includes a water circulation system and a replaceable water filter. The refrigerator includes a sensor that determines if a water filter is present, and a user interface that prompts a user to purge a water filter upon installation of a new water filter in the refrigerator. The water filter may include a memory storage device that stores information concerning the allowable life of the water filter, the remaining life of the water filter, and other information. Information concerning the remaining life of the water filter and other information can be displayed or otherwise communicated to a user by the user interface.

A pressurized metered dose dispenser (100) for dispensing an aerosol formulation comprising particles of a medicament suspended in liquefied propellant, optionally in combination with one or more excipients, the dispenser comprising an aerosol container (1) equipped with a metered dose valve (10), where a formulation chamber is defined in part by the internal walls of the container, and wherein the dispenser further comprises a porous, fluid permeable, particulate semi-permeable body (40) located within the formulation chamber adjacent to the metered dose valve.

A pressurized dispenser includes a base and a peripheral wall having an open end sealed by a dispensing element comprising a dip-tube, a fluid reservoir in contact with the dip-tube for reducing the compressed gas lost from the pressurized dispenser, a compressed gas and a dispensing liquid. In embodiments, a majority of the fluid reservoir may be located outside of the dip-tube, and the fluid reservoir may include a porous material, arranged in use to hold a volume of the dispensing liquid. Such porous material may be configured so that, in use, at least a portion of any compressed gas in the reservoir can be displaced by the liquid, ejecting such portion of the compressed gas into the dispenser. In embodiments, the dispensing element may be configured to dispense dispensing liquid continuously for at least 0.5 seconds, upon actuation of the dispensing element.

An inhalation device including a housing, which encloses a liquid reservoir in which the liquid is stored before discharge, and an applicator head with a nebulization chamber and an applicator piece connected thereto, wherein the applicator piece is designed either as a mouthpiece, to be received in the mouth of a patient, or as an inhalation mask, to sealingly cover the mouth, the nose, or the mouth and the nose. The inhalation device furthermore has a discharge channel which connects the liquid reservoir to the applicator head. The inhalation device includes at the end of the discharge channel, a nozzle plate with a large number of nozzle openings which serve to generate an inhalation mist and through which the liquid from the liquid reservoir is conveyed into the nebulization chamber.

Two sub-methods are used together to produce a nozzle unit for a liquid dispenser. The methods include adding a nozzle plate into a nozzle channel of a nozzle unit using an assembly tool which elastically expands the nozzle channel. The assembly tool is inserted in the nozzle channel and expands same, thus moving the nozzle plate into its final position where it remains after the assembly tool is removed. The methods also include attaching a filter to a nozzle unit carrier. In a preparation step, a flat filter material is positioned on the end face of the carrier. Only after the filter material is positioned and a connection of the filter material to the end face is established, a separation process is carried out by which the filter material is cut to surround the end face. The filter material positioned on the end face and cut in situ remains.

Embodiments herein describe a portable device for administering a physiologically active liquid that includes a container for holding the liquid, a pressure system for applying pressure to the liquid, an atomizer for atomizing the liquid, and an applicator for administering atomized liquid. The atomizer includes at least one nozzle through which liquid can be ejected from the container and an impact element on the nozzle outlet side that is functionally combined with the nozzle. Moreover, the atomizer is configured in such a way that, in a pressure range that can be generated with the pressurizing system, liquid emerging from the nozzle breaks up into droplets prior to striking the impact element.