An animal ear tag for marking livestock, in particular cattle, pigs, goats and sheep. The animal ear tag comprises a plastic, wherein an antimicrobial additive is incorporated into the plastic.

Genetic tests, such as whole genome analysis (WGA), have been employed to identify genetically superior embryos. The disclosed methods extend in vitro culture time of embryos while awaiting results of genetic tests being performed on a portion of the same embryos. The disclosed methods also help expand the number of cells in each embryo before implantation in the recipient.

The present disclosure provides genetically modified heterogametic organism that comprises a genetically modified first sex chromosome comprising at least one exogenous nucleic acid sequence integrated therein. In more specific embodiments, the exogenous nucleic acid sequence comprises (i) at least one nucleic acid sequence encoding at least one nucleic acids modifier component, and further (ii) at least one nucleic acid sequence encoding and/or forming at least one target recognition element for the at least one nucleic acids modifier component of (i). The present disclosure further comprises systems comprising the discussed genetically modified heterogametic organism, methods and uses thereof in biasing sex-ratio of populations.

An evaluating method includes an evaluating step of performing a first evaluation of evaluating a state of a metabolic disease in a cow after present parturition, using a first value in the cow before present parturition, a value of a formula calculated using the first value and the formula including an explanatory variable to be substituted with the first value, or a graph generated based on the first value, the first value being a value on cattle management information obtainable by a non-invasive method.

A system and method for calculating an estimate of a body condition score (BCS) for a bovine animal is described. The system comprises a visual spectrum camera configured to collect visual spectrum data of the animal in an area of interest, an infra-red camera configured to collect near infra-red spectrum data of the animal related to soft tissue distribution around the area of interest, and one or more neural networks trained using a first training dataset comprising combined imaging data for each of a plurality of animals and corresponding BCS's for the plurality of animals, in which the combined imaging data for each animal comprises the visual spectrum data and the near infra-red spectrum data for the animal. The system also includes a processor configured to: receive the combined imaging data for the animal and apply the one or more neural networks to the combined imaging data for the animal to calculate an estimate of a BCS for the animal.

The instant disclosure provides multiple precision edits of bovine integrin beta 2 (CD18) that confer reduced susceptibility to Manheimia haemolytica leukotoxin A (LktA). Further disclosed are methods of producing genome-edited bovine cells, embryos, and animals comprising a modified CD18 incorporating the precision edits.

Described in several exemplary embodiments herein are germline complementation methods and compositions, particularly NANOS3 deficient cells and non-human animals. In some embodiments, the NANOS3 deficient non-human animals are germline ablated.

A feedback device includes an acquisition unit configured to acquire a BCS evaluation value obtained by evaluating a BCS value representing a body condition score of livestock with a reference value for evaluating the BCS value and a feedback unit configured to output feedback information concerning the livestock based on the acquired BCS evaluation value.

Provided herein are isolated nucleic acids, vectors, recombinant cells, and transgenic animals capable of expressing at least one or more bluebuck gene variants associated with gray/blue coat color and/or melanogenesis and/or altered facial pattern. Also provided are methods of making recombinant cells and/or transgenic animals that comprise at least one bluebuck (Hippotragus leucophaeus) gene variant associated with gray/blue coat color and/or melanogenesis and/or altered facial pattern.