Described herein are methods and compositions for modulating bovine birth rate by following a breeding scheme based on the presence of the trio haplotype, which is strongly linked to the propensity to give birth to multiple calves in one event.

Described herein are methods and compositions for modulating bovine birth rate by following a breeding scheme based on the presence of the trio haplotype, which is strongly linked to the propensity to give birth to multiple calves in one event.

The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.

The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.

A method of increasing the probability of breeding swine via a lighting system with a programmable timing device. The lighting system is programmed to present differing photoperiods such that the amount of light observed by a swine every day or week gradually decreases, mimicking a seasonal change, typically from summer to fall. As a result, swine psychologically and physiologically believe that seasons are changing resulting in increased probability of breeding for the swine.

A method of increasing the probability of breeding swine via a lighting system with a programmable timing device. The lighting system is programmed to present differing photoperiods such that the amount of light observed by a swine every day or week gradually decreases, mimicking a seasonal change, typically from summer to fall. As a result, swine psychologically and physiologically believe that seasons are changing resulting in increased probability of breeding for the swine.

The invention relates to processes for mitochondrial microinjection in oocytes. The processes involve isolating mammalian mitochondria for microinjection in oocytes to increase their mitochondrial activity. Microinjected mitochondria may be isolated from mammalian platelets and incubated in a favorable medium prior to microinjection. Oocytes that are microinjected with mitochondria obtained from the processes of the invention are shown to have a higher rate of fertilization and blastocyst formation when the processes disclosed herein are used concurrently with in vitro fertilization procedures. The invention relates generally to a process for treating deficiencies in mitochondrial activity in oocytes, a process for isolating mitochondria from mammalian platelets, and/or a process for preparing mitochondria for microinjection in oocytes.

The invention relates to processes for mitochondrial microinjection in oocytes. The processes involve isolating mammalian mitochondria for microinjection in oocytes to increase their mitochondrial activity. Microinjected mitochondria may be isolated from mammalian platelets and incubated in a favorable medium prior to microinjection. Oocytes that are microinjected with mitochondria obtained from the processes of the invention are shown to have a higher rate of fertilization and blastocyst formation when the processes disclosed herein are used concurrently with in vitro fertilization procedures. The invention relates generally to a process for treating deficiencies in mitochondrial activity in oocytes, a process for isolating mitochondria from mammalian platelets, and/or a process for preparing mitochondria for microinjection in oocytes.

The present invention provides method of classifying a subject into a necrotizing meningoencephalitis (NME) disease risk group. The method may include assessing the presence of one or more marker (e.g., SNPs or risk loci) in a sample from the subject. For example, detection of the presence of one or more markers that are associated with an increased risk of NME can indicate that the subject should be classified into a risk group.

The present invention provides methods for estimating the breeding value of individuals in populations such as those having small effective population size (Ne) e.g., to identify selection candidates having high breeding values, wherein the methods comprise inferring one or more genotypes for one or more markers at a locus or QTL to be the same as for an ancestor or founder or a subset of ancestors and/or founders from which a corresponding chromosome segment is derived and estimating the breeding value of the individual based on the inferred genotype(s).