The present invention provides a controlled release formulation comprising a silicone substrate which comprises a compound of Formula (I): AA-AA-AA-X—Y. The invention further provides methods of making these formulations, medical devices such as dressings incorporating said formulations and medical uses thereof.

Architectural structures including an inorganic material carrier including cement and particles or fibers of a glass including a plurality of Cu.sup.1+ ions. In aspects, the glass may have a glass phase and a cuprite phase. In aspects, the glasses may include a plurality of Cu.sup.1+ ions, a degradable phase including B.sub.2O.sub.3, P.sub.2O.sub.5 and K.sub.2O and a durable phase including SiO.sub.2. In other aspects, the glass can have a plurality of Cu.sup.1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The glasses and articles disclosed herein can exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing condition and under Modified JIS Z 2801 for Bacteria testing conditions.

Architectural structures including an inorganic material carrier including cement and particles or fibers of a glass including a plurality of Cu.sup.1+ ions. In aspects, the glass may have a glass phase and a cuprite phase. In aspects, the glasses may include a plurality of Cu.sup.1+ ions, a degradable phase including B.sub.2O.sub.3, P.sub.2O.sub.5 and K.sub.2O and a durable phase including SiO.sub.2. In other aspects, the glass can have a plurality of Cu.sup.1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The glasses and articles disclosed herein can exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing condition and under Modified JIS Z 2801 for Bacteria testing conditions.

Architectural structures including an inorganic material carrier including cement and particles or fibers of a glass including a plurality of Cu.sup.1+ ions. In aspects, the glass may have a glass phase and a cuprite phase. In aspects, the glasses may include a plurality of Cu.sup.1+ ions, a degradable phase including B.sub.2O.sub.3, P.sub.2O.sub.5 and K.sub.2O and a durable phase including SiO.sub.2. In other aspects, the glass can have a plurality of Cu.sup.1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The glasses and articles disclosed herein can exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing condition and under Modified JIS Z 2801 for Bacteria testing conditions.

A method for embedding a first component in a high molecular weight second component is disclosed. Embedded high-molecular-weight compositions are also disclosed.

This invention relates to the field of control of different fungal diseases in the agricultural industry. Specifically, the invention reports conjugates between biopolymers and a photoactivable agent, which when activated by light generates singlet oxygen, a species known for its antimicrobial capacity. The invention also relates to methods of production of these conjugates and their uses.

This invention relates to the field of control of different fungal diseases in the agricultural industry. Specifically, the invention reports conjugates between biopolymers and a photoactivable agent, which when activated by light generates singlet oxygen, a species known for its antimicrobial capacity. The invention also relates to methods of production of these conjugates and their uses.

An ultrasound probe with antimicrobial surface activity includes a housing, wherein the housing has an antimicrobial compound present at an exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity with microbes that contact the exterior surface of the ultrasound probe. A plurality of antimicrobial compounds may be present at the exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity. The antimicrobial compound may be an additive to a polymeric material from which the probe housing is manufactured. The antimicrobial compound may be present in an antimicrobial coating disposed on the exterior surface of the probe housing. The antimicrobial activity may provide log reductions in gram+ and gram− bacteria after 24 hours in the range from 3 to 7.

An ultrasound probe with antimicrobial surface activity includes a housing, wherein the housing has an antimicrobial compound present at an exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity with microbes that contact the exterior surface of the ultrasound probe. A plurality of antimicrobial compounds may be present at the exterior surface of the probe housing in sufficient concentration to provide antimicrobial activity. The antimicrobial compound may be an additive to a polymeric material from which the probe housing is manufactured. The antimicrobial compound may be present in an antimicrobial coating disposed on the exterior surface of the probe housing. The antimicrobial activity may provide log reductions in gram+ and gram− bacteria after 24 hours in the range from 3 to 7.

Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.