An antimicrobial composition includes an aqueous carrier and a surfactant system. The surfactant system includes a first surfactant including a first polyethylene glycol (PEG) compound with an HLB value of greater than about 10 and less than about 14, and a second surfactant different from the first surfactant, wherein the second surfactant has an HLB value less than about 10.

A composite quaternary ammonium salt disinfectant includes a double long-chain quaternary ammonium salt, two single long-chain quaternary ammonium salts, a synergist isothiazolinone, a nonionic surfactant fatty alcohol polyvinyl ether, and water, wherein the double long-chain quaternary ammonium salt is dialkyl dimethyl ammonium chloride with dialkyl being two independent alkyl groups with a chain length of C8-C18, and the two single-chain quaternary ammonium salts are alkyl dimethyl benzyl ammonium chloride with an alkyl chain length of C8-C18 and alkyl dimethyl ethyl benzyl ammonium chloride with an alkyl chain length of C8-C18, respectively. The composite quaternary ammonium salt disinfectant has a synergistic effect among its components, which greatly improves the capacity of resisting interferences by hard water and organics; and can kill not only bacterial propagules, lipophilic viruses (enveloped viruses, such as novel coronavirus) and fungi, but also hydrophilic viruses (non-enveloped viruses).

A composite quaternary ammonium salt disinfectant includes a double long-chain quaternary ammonium salt, two single long-chain quaternary ammonium salts, a synergist isothiazolinone, a nonionic surfactant fatty alcohol polyvinyl ether, and water, wherein the double long-chain quaternary ammonium salt is dialkyl dimethyl ammonium chloride with dialkyl being two independent alkyl groups with a chain length of C8-C18, and the two single-chain quaternary ammonium salts are alkyl dimethyl benzyl ammonium chloride with an alkyl chain length of C8-C18 and alkyl dimethyl ethyl benzyl ammonium chloride with an alkyl chain length of C8-C18, respectively. The composite quaternary ammonium salt disinfectant has a synergistic effect among its components, which greatly improves the capacity of resisting interferences by hard water and organics; and can kill not only bacterial propagules, lipophilic viruses (enveloped viruses, such as novel coronavirus) and fungi, but also hydrophilic viruses (non-enveloped viruses).

A composite quaternary ammonium salt disinfectant includes a double long-chain quaternary ammonium salt, two single long-chain quaternary ammonium salts, a synergist isothiazolinone, a nonionic surfactant fatty alcohol polyvinyl ether, and water, wherein the double long-chain quaternary ammonium salt is dialkyl dimethyl ammonium chloride with dialkyl being two independent alkyl groups with a chain length of C8-C18, and the two single-chain quaternary ammonium salts are alkyl dimethyl benzyl ammonium chloride with an alkyl chain length of C8-C18 and alkyl dimethyl ethyl benzyl ammonium chloride with an alkyl chain length of C8-C18, respectively. The composite quaternary ammonium salt disinfectant has a synergistic effect among its components, which greatly improves the capacity of resisting interferences by hard water and organics; and can kill not only bacterial propagules, lipophilic viruses (enveloped viruses, such as novel coronavirus) and fungi, but also hydrophilic viruses (non-enveloped viruses).

A method of controlling a biofilm comprises contacting the biofilm with probiotic species and contacting the biofilm with chemical disinfectant. The biofilm may be contacted with the probiotic species and the chemical disinfectant simultaneously or sequentially. The method provides a higher reduction in the amount of at least one microbial species in the biofilm, compared to a similar method applying only the chemical disinfectant. Furthermore, the method may provide an unexpected synergy between the probiotic species and the chemical disinfectant in controlling the biofilm.

A method of controlling a biofilm comprises contacting the biofilm with probiotic species and contacting the biofilm with chemical disinfectant. The biofilm may be contacted with the probiotic species and the chemical disinfectant simultaneously or sequentially. The method provides a higher reduction in the amount of at least one microbial species in the biofilm, compared to a similar method applying only the chemical disinfectant. Furthermore, the method may provide an unexpected synergy between the probiotic species and the chemical disinfectant in controlling the biofilm.

A method of controlling a biofilm comprises contacting the biofilm with probiotic species and contacting the biofilm with chemical disinfectant. The biofilm may be contacted with the probiotic species and the chemical disinfectant simultaneously or sequentially. The method provides a higher reduction in the amount of at least one microbial species in the biofilm, compared to a similar method applying only the chemical disinfectant. Furthermore, the method may provide an unexpected synergy between the probiotic species and the chemical disinfectant in controlling the biofilm.

Disclosed herein is a shelf-stable, two-part formula for making an antimicrobial biphasic polymer. Some variations provide a two-part formula for fabricating a biphasic polymer, wherein the two-part formula consists essentially of (A) a first liquid volume, wherein the first liquid volume comprises: a structural phase containing a solid structural polymer; a transport phase containing a solid transport polymer; a chain extender; a curing catalyst; a first solvent; and (B) a second liquid volume that is volumetrically isolated from the first liquid volume, wherein the second liquid volume comprises: a crosslinker that is capable of crosslinking the solid structural polymer with the solid transport polymer; and a second solvent. An antimicrobial agent (e.g., quaternary ammoniums salts) may be contained in the first liquid volume or in the second liquid volume. Methods of making and using the antimicrobial biphasic polymer are described.

Disclosed herein is a shelf-stable, two-part formula for making an antimicrobial biphasic polymer. Some variations provide a two-part formula for fabricating a biphasic polymer, wherein the two-part formula consists essentially of (A) a first liquid volume, wherein the first liquid volume comprises: a structural phase containing a solid structural polymer; a transport phase containing a solid transport polymer; a chain extender; a curing catalyst; a first solvent; and (B) a second liquid volume that is volumetrically isolated from the first liquid volume, wherein the second liquid volume comprises: a crosslinker that is capable of crosslinking the solid structural polymer with the solid transport polymer; and a second solvent. An antimicrobial agent (e.g., quaternary ammoniums salts) may be contained in the first liquid volume or in the second liquid volume. Methods of making and using the antimicrobial biphasic polymer are described.

A non-toxic, alcohol-free disinfectant and sanitizing composition comprising a non-ionic surfactant system, an alkylated vegetable oil, a sodium-containing base, benzalkonium chloride, citric acid and purified water for use on skin, hands and hard surfaces. The materials from which it is manufactured are all renewable, non-toxic, alcohol-free, nonflammable and the composition is readily biodegradable. The composition does not rely upon alcohol to produce its antimicrobial effects. The invention provides effective alternative to alcohol-based disinfectant and sanitizers and may be particularly useful in personal care and cleaning household products for schools, hospitals, restaurants, hotels and supermarkets. Furthermore, the invention also met the Environmental Protection Agency (EPA) standards and protocols for disinfectants on hard surfaces.