The present invention relates to novel combinations of active compounds comprising, novaluron and at least one further active compound, and to methods of controlling pests comprising applying said combinations.

The present invention relates to novel combinations of active compounds comprising, novaluron and at least one further active compound, and to methods of controlling pests comprising applying said combinations.

A high through-put screening method for identifying agents effective for inhibiting biofilm formation and/or killing established biofilm are disclosed. The method includes three tiers, and each tier includes three specific biological process assays. The tier levels are a primary screen, a confirmation screen, and a dose-response screen, and the biological process assays include assays for total bacterial growth, bacterial metabolic activity, and biofilm formation. The series of assays may be run once or more than once at each tier. A library of compounds is subject to tier A and only compounds meeting a primary parameter advance to tier B, and only tier B compounds meeting a confirmation parameter advance to tier C, and only tier C compounds meeting a dose-response parameter are identified as putative agents effective for inhibiting and/or eradicating a biofilm, further wherein the assays are conducted for each compound subject to the respective tier. The method is effective and validated for identifying agents which inhibit and/or kill Staphylococcus epidermidis, Pseudomonas aeruginosa, and Acinetobacter baumannii biofilms. Agents identified according to the high through-put screen and validated in follow-up experiments as effective for inhibiting and/or killing bacterial biofilms are also disclosed.

A high through-put screening method for identifying agents effective for inhibiting biofilm formation and/or killing established biofilm are disclosed. The method includes three tiers, and each tier includes three specific biological process assays. The tier levels are a primary screen, a confirmation screen, and a dose-response screen, and the biological process assays include assays for total bacterial growth, bacterial metabolic activity, and biofilm formation. The series of assays may be run once or more than once at each tier. A library of compounds is subject to tier A and only compounds meeting a primary parameter advance to tier B, and only tier B compounds meeting a confirmation parameter advance to tier C, and only tier C compounds meeting a dose-response parameter are identified as putative agents effective for inhibiting and/or eradicating a biofilm, further wherein the assays are conducted for each compound subject to the respective tier. The method is effective and validated for identifying agents which inhibit and/or kill Staphylococcus epidermidis, Pseudomonas aeruginosa, and Acinetobacter baumannii biofilms. Agents identified according to the high through-put screen and validated in follow-up experiments as effective for inhibiting and/or killing bacterial biofilms are also disclosed.

The disclosure concerns an oil flowable formulation comprising a first active compound having a structure

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and a lipophilic solvent, a first dispersant, and a rheology modifier. The formulation comprises particles of the first active compound having a median particle size, as measured by light scattering, of from 0.1 to 20 microns. The formulation may also comprise an emulsifier, a second dispersant, and/or an agriculturally active compound, such as an acaricide, antimicrobial, fungicide, herbicide, insecticide, molluscicide, or nematocide, or a combination thereof. Also disclosed are agricultural compositions comprising the formulation and methods of using the same.

The disclosure concerns an oil flowable formulation comprising a first active compound having a structure

##STR00001##

and a lipophilic solvent, a first dispersant, and a rheology modifier. The formulation comprises particles of the first active compound having a median particle size, as measured by light scattering, of from 0.1 to 20 microns. The formulation may also comprise an emulsifier, a second dispersant, and/or an agriculturally active compound, such as an acaricide, antimicrobial, fungicide, herbicide, insecticide, molluscicide, or nematocide, or a combination thereof. Also disclosed are agricultural compositions comprising the formulation and methods of using the same.

Disclosed herewith is a method of using N-hydroxycarboxamide compound based metabolic inhibitor composition, which has demonstrated efficacy for controlling biofilms formed by sulfate reducing prokaryotes. This composition is suitable for use in downhole, drilling and exploration application environments and in equipment like rigs, semi-submersibles, storage and base structures. It can also be used in other harsh environment applications, including mining, industrial extraction of metals and sewage treatment, as well as non-harsh environment applications.

Disclosed herewith is a method of using N-hydroxycarboxamide compound based metabolic inhibitor composition, which has demonstrated efficacy for controlling biofilms formed by sulfate reducing prokaryotes. This composition is suitable for use in downhole, drilling and exploration application environments and in equipment like rigs, semi-submersibles, storage and base structures. It can also be used in other harsh environment applications, including mining, industrial extraction of metals and sewage treatment, as well as non-harsh environment applications.

The present invention provides methods of regulating plant stress tolerance.

The present invention provides methods of regulating plant stress tolerance.