Disclosed are compounds of Formula 1 including all geometric and stereoisomers, N-oxides, and salts thereof,

##STR00001##

wherein Z, X, R.sup.1, R.sup.2, W, R.sup.3, R.sup.4a, R.sup.4b, L, R.sup.5a, R.sup.5b and Q are as defined in the disclosure.

Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

Disclosed are compounds of Formula 1 including all geometric and stereoisomers, N-oxides, and salts thereof,

##STR00001##

wherein Z, X, R.sup.1, R.sup.2, W, R.sup.3, R.sup.4a, R.sup.4b, L, R.sup.5a, R.sup.5b and Q are as defined in the disclosure.

Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

Provided is an engineered antimicrobial peptide. Also provided is a composition comprising an engineered antimicrobial peptide. Provided is a method of treating a subject in need thereof, comprising administering a therapeutically effective amount of a composition comprising an engineered antimicrobial peptide. Also provided is a method of producing an engineered antimicrobial peptide.

Provided is an engineered antimicrobial peptide. Also provided is a composition comprising an engineered antimicrobial peptide. Provided is a method of treating a subject in need thereof, comprising administering a therapeutically effective amount of a composition comprising an engineered antimicrobial peptide. Also provided is a method of producing an engineered antimicrobial peptide.

A novel agrochemical formulation comprising adjuvants selected from ilicicolins and lamellicolic anhydrides and an agrochemical active is described. A concentrate is also provided suitable for forming the formulation. The ilicicolins and lamellicolic anhydrides provide adjuvancy in the concentrate and agrochemical formulation. Use of said ilicicolins and lamellicolic anhydrides as adjuvants in agrochemical formulations is also provided. There is also provided a method of making the formulation, and for treating soil with the formulations. A method of obtaining the ilicicolins and lamellicolic anhydrides from culturing of Cosmospora sp., strain RKD01747 is also described.

A novel agrochemical formulation comprising adjuvants selected from ilicicolins and lamellicolic anhydrides and an agrochemical active is described. A concentrate is also provided suitable for forming the formulation. The ilicicolins and lamellicolic anhydrides provide adjuvancy in the concentrate and agrochemical formulation. Use of said ilicicolins and lamellicolic anhydrides as adjuvants in agrochemical formulations is also provided. There is also provided a method of making the formulation, and for treating soil with the formulations. A method of obtaining the ilicicolins and lamellicolic anhydrides from culturing of Cosmospora sp., strain RKD01747 is also described.

A phytoregulator composition including L-proline, kaolin, and optionally brown algae in wettable powder form for use in plants in flowering and fruiting stages of life is provided.

A phytoregulator composition including L-proline, kaolin, and optionally brown algae in wettable powder form for use in plants in flowering and fruiting stages of life is provided.

This disclosure provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.

This disclosure provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.