A method for controlling PPO resistant weeds, wherein compounds of formula (I)

##STR00001## wherein the variables are defined as given in the description and claims;
are applied to the PPO inhibitor herbicide resistant weed, parts of it or its propagation material.

In crop production in the fields of agriculture, horticulture and the like, the damage caused by insect pests etc. is still immense, and insect pests resistant to existing insecticides have emerged. Under such circumstances, the development of novel agricultural and horticultural insecticides is desired. The present invention provides an amide compound represented by the general formula (I):

##STR00001##

(wherein A.sup.1, A.sup.2 and A.sup.3 each represent a nitrogen atom or a CH group, R.sup.1 represents an alkyl group, R.sup.2 and R.sup.4 each represent a haloalkyl group, R.sup.3 represents an alkyl group, and m represents 0, 1 or 2) or a salt thereof; an agricultural and horticultural insecticide and microbicide comprising the compound or a salt thereof as an active ingredient; and a method for using the insecticide and microbicide.

In crop production in the fields of agriculture, horticulture and the like, the damage caused by insect pests etc. is still immense, and insect pests resistant to existing insecticides have emerged. Under such circumstances, the development of novel agricultural and horticultural insecticides is desired. The present invention provides an amide compound represented by the general formula (I):

##STR00001##

(wherein A.sup.1, A.sup.2 and A.sup.3 each represent a nitrogen atom or a CH group, R.sup.1 represents an alkyl group, R.sup.2 and R.sup.4 each represent a haloalkyl group, R.sup.3 represents an alkyl group, and m represents 0, 1 or 2) or a salt thereof; an agricultural and horticultural insecticide and microbicide comprising the compound or a salt thereof as an active ingredient; and a method for using the insecticide and microbicide.

The present invention relates to herbicidal mixture comprising L-glufosinate or its salt and at least one bleacher herbicide. The invention furthermore relates to a method for controlling undesirable vegetation in burndown programs, in industrial vegetation management and forestry, in vegetable and perennial crops and in turf and lawn.

The present invention relates to herbicidal mixture comprising L-glufosinate or its salt and at least one bleacher herbicide. The invention furthermore relates to a method for controlling undesirable vegetation in burndown programs, in industrial vegetation management and forestry, in vegetable and perennial crops and in turf and lawn.

The present invention is directed to agricultural compositions comprising at least one agriculturally active ingredient and gellan gum. The present invention is further directed to tank mixes comprising a high electrolyte composition comprising at least one agriculturally active ingredient and a second composition comprising at least one agriculturally active ingredient, wherein gellan gum is present in the high electrolyte composition or the second composition or is added to the tank mix.

The present invention is directed to agricultural compositions comprising at least one agriculturally active ingredient and gellan gum. The present invention is further directed to tank mixes comprising a high electrolyte composition comprising at least one agriculturally active ingredient and a second composition comprising at least one agriculturally active ingredient, wherein gellan gum is present in the high electrolyte composition or the second composition or is added to the tank mix.

The present invention is directed to agricultural compositions comprising at least one agriculturally active ingredient and gellan gum. The present invention is further directed to tank mixes comprising a high electrolyte composition comprising at least one agriculturally active ingredient and a second composition comprising at least one agriculturally active ingredient, wherein gellan gum is present in the high electrolyte composition or the second composition or is added to the tank mix.

Identification and evaluation of a set of first-in-class potent inhibitors targeting a new cancer target, Grb2-associated binder˜1 (GAB1), which integrates signals from different signaling pathways and is frequently over-expressed in cancer ceils. Intensive computational modeling is utilized to understand the structure of the GAB1 pleckstrin homology (PH) domain and screened five million compounds. Upon biological evaluation, several inhibitors were found that induced large conformational changes of the target structure exhibited strong selective binding to GAB1 PH domain. Particularly, these inhibitors demonstrated potent and tumor-specific cytotoxicity in breast cancer cells. This targeting GAB1 signaling may be used for cancer therapy, especially for triple negative breast cancer patients.

Identification and evaluation of a set of first-in-class potent inhibitors targeting a new cancer target, Grb2-associated binder˜1 (GAB1), which integrates signals from different signaling pathways and is frequently over-expressed in cancer ceils. Intensive computational modeling is utilized to understand the structure of the GAB1 pleckstrin homology (PH) domain and screened five million compounds. Upon biological evaluation, several inhibitors were found that induced large conformational changes of the target structure exhibited strong selective binding to GAB1 PH domain. Particularly, these inhibitors demonstrated potent and tumor-specific cytotoxicity in breast cancer cells. This targeting GAB1 signaling may be used for cancer therapy, especially for triple negative breast cancer patients.