This invention relates to a method for treating atopic dermatitis, comprising administering an effective amount of N-acyltryptamine represented by Formula (I): ##STR00001##
wherein R represents a saturated aliphatic hydrocarbon group having 2 to 29 carbon atoms; or a pharmaceutically acceptable salt, hydrate or solvate thereof to a subject in need thereof.

A method for determining one or more tumour properties in a subject with a tumour, the method comprising:—seeding a cell-free scaffold obtained from the tumour with cancer cells;—culturing the cancer cells in the scaffold;—assaying the cultured cancer cells for the presence of target molecules indicative of the expression of one or more genes in the cells; and—determining one or more tumour properties based on the results of the assay.

The present disclosure relates to anti-microbial polymers comprising a polymerizable cyclic moiety which forms part of the backbone of the polymer.

The present disclosure relates to antimicrobial polymers which impart prolonged antimicrobial activity to a surface or in a solution, the polymers comprising as repeating monomers a polymerizable cyclic moiety forming part of the polymer backbone and an anti-microbial moiety such as a quaternary ammonium moiety in the side chain. The polymer may further comprise polymerizable units of at least one unsaturated monomer having an ethylenically unsaturated double or triple bond.

The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages. Various active ingredients may be incorporated, such as immunosuppressants, antiinfectives, antifungal agents, antiinflammatory agents, and retinoids.

The invention relates to a compound capable of blocking the absorption of heavy metals by plants and a composition containing the same. The compound was extracted from Aegiceras corniculatum. The compound is extracted by enzyme extraction, filtration, concentrating and drying. The compound is derived from natural plants, and no organic solvents are used in the extraction process. The compound and the composition formed by the compound have a certain barrier effect on the absorption of heavy metals by plants. ##STR00001##

Provided herein are stable amlodipine oral liquid formulations. Also provided herein are methods of using amlodipine oral liquid formulations for the treatment of certain diseases including hypertension and Coronary Artery Disease (CAD).

Provided is an orthopedic implant comprising a surface with a coating on the surface wherein the coating comprises a copolymer defined by Formula I: A.sub.w-B.sub.x-C.sub.y-D.sub.z wherein: A comprises an epoxy group; B comprises a hydrophobic group; C is an optional cross-linker; D of Formula I comprises a hydrophilic group; w is at least 0.1 to no more than 0.9 with the proviso that at least one of x or z is not zero; x is up to 0.9; y is up to 0.3; and z is up to 0.9.

Provided is an orthopedic implant comprising a surface with a coating on the surface wherein the coating comprises a copolymer defined by Formula I: A.sub.w-B.sub.x-C.sub.y-D.sub.z wherein: A comprises an epoxy group; B comprises a hydrophobic group; C is an optional cross-linker; D of Formula I comprises a hydrophilic group; w is at least 0.1 to no more than 0.9 with the proviso that at least one of x or z is not zero; x is up to 0.9; y is up to 0.3; and z is up to 0.9.

Provided herein are stable amlodipine oral liquid formulations. Also provided herein are methods of using amlodipine oral liquid formulations for the treatment of certain diseases including hypertension and Coronary Artery Disease (CAD).