This invention relates generally to a process for selective adsorption and recovery of lithium from natural and synthetic brines, and more particular to a process for recovering lithium from a natural or synthetic brine solution by passing the brine solution through a lithium selective adsorbent in a continuous countercurrent adsorption and desorption circuit.

A gas separation device for use in combination with a liquid chromatography system is provided. The gas separation device includes a housing defining a fluid flow path between an outer surface and an inner surface. The fluid flow path includes an inlet portion, a diffuser portion, a recombination portion, and an outlet portion. Any gas bubbles contained within the fluid are trapped within the diffusor portion when fluid flow is in a forward direction. Fluid flow through the gas separation device is reversable so as to remove the trapped gas bubbles from within the gas separation device. In this operation state, the fluid is delivered from the gas separation device into the waste stream to ensure that gas bubbles leave the liquid chromatography system. The gas separation device may exhibit an air trapping effectiveness ratio (ATER) between 0.001 mb.sup.1 and 0.51 mb.sup.1 during forward direction fluid flow.

Disclosed is a method for removing factor XI (FXI) during plasma protein purification, more specifically a method for removing FXI including dialyzing and concentrating a plasma protein fraction II paste containing FXI and a plasma protein, and then removing the FXI using ceramic-based cation exchange resin. The method for removing factor XI (FXI) can improve removal efficiency of impurities and thrombogenic substances, thereby producing stable plasma proteins with improved quality.

Disclosed here includes a method for purifying a biologic composition, comprising diafiltering the biologic composition into a composition comprising phosphate buffered saline (PBS) to obtain a purified composition. The method disclosed here can be particularly useful for removing one or more impurities from the biologic composition, such as bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane (Bis-tris).

A sample injector is provided for a chromatography system that includes a mobile phase drive and a separation unit. The mobile phase drive is configured for driving a mobile phase through the separation unit, and the separation unit is configured for chromatographically separating compounds of a sample fluid in the mobile phase. The sample injector is configured for injecting the sample fluid into the mobile phase and comprises a needle and a handling unit configured for positioning the needle. Operating the sample injector includes providing a receptacle that includes a filtration unit configured for filtering a sample fluid comprised within the receptacle, moving the filtration unit within the receptacle in order to filter at least a portion of the sample fluid contained in the receptacle, operating the handling unit to position the needle into the receptacle, and aspirating a volume of the filtered sample fluid.

The present invention relates to the process of enrichment of Phytocannabinoids namely CBD and .sup.9-THC from the dried aerial part (leaves and inflorescence) of Cannabis sativa. The present invention also relates to the preparation of formulation having enriched CBD and THC by combining with appropriate acceptable excipients such as nutriose, dextrin and maltodextrin. The present invention also discloses the use of the phytocannabanoids enriched blend for the management of pain including cancer pain & general pain.

Disclosed here includes a method for purifying a biologic composition, comprising diafiltering the biologic composition into a composition comprising phosphate buffered saline (PBS) to obtain a purified composition. The method disclosed here can be particularly useful for removing one or more impurities from the biologic composition, such as bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane (Bis-tris).

Example implementations relate to techniques for thermal fluid conditioning and delivery. A technique may involve coupling a container of heat transfer fluid to an input and removing moisture from the heat transfer fluid via a molecular sieve. A pressure source is configured to push the heat transfer fluid out of the container and through the molecular sieve. Subsequent to removing the moisture from the heat transfer fluid, the technique involves separating, via an orifice coupled to a tank, the heat transfer fluid into liquid and gas particles within the tank and removing, via a vacuum coupled to the tank, the gas particles from the tank. The liquid can then be supplied into a fluid system via additional pressure by the pressure source. The technique may be performed by a portable device that houses the various components used to condition and delivery the thermal fluid.

A chromatography analysis apparatus (30) comprises: a fractionation device (32) for receiving a sample, the fractionation device (32) defining a sample flow path that includes a guard column; and a fractionation output analyser (34), wherein a fractionation output of the guard column is provided to an input of the fractionation output analyser (34) for enabling subsequent analysis of the fractionation output by the fractionation output analyser (34).

In some examples, a filter assembly may include a filter including a first gasket having a first channel adjacent to a first side of the filter and a second gasket having a second channel adjacent to a second side of the filter. The first gasket and the second gasket may include a beveled surface adjacent to the filter. The first channel and the second channel may include a diameter of from about 0.01 mm to about 0.5 mm. A finger tightening system may securely hold the filter without any leaks.