A method comprising a first pump unit delivering a first flow of a first solvent at a first flow rate, and a second pump unit delivering a second flow of a second solvent at a second flow rate. At a first process stage of the first run when the first flow rate exceeds the second flow rate, the first pump unit assuming a first pump unit state, in the second run, at a first process stage of the second run, setting the first pump unit to the first pump unit state. At a second process stage of the first run when the second flow rate exceeds the first flow rate, the second pump unit assuming a second pump unit state, and in the second run, at a second process stage of the second run, setting the second pump unit to the second pump unit state.

A sample management device which comprises a source flow path in which a fluidic sample can flow, a volume flow adjustment unit configured for adjusting a volume flow of the fluidic sample to be branched off from the source flow path at a fluidic coupling point, and a fluidic valve fluidically coupled with the source flow path and with the volume flow adjustment unit, wherein the fluidic valve is switchable into a branch off state in which the fluidic coupling point is established within the source flow path to branch off an adjustable volume of the fluidic sample from the source flow path via the fluidic coupling point while a flow of the fluidic sample in the source flow path continues.

A method for controlling fluid flowing through a chromatographic system includes determining a fluidic parameter related to density at a first fluidic location in the chromatographic system; and in response to the determined fluidic parameter, modifying a volumetric flow rate or a pressure at a second fluidic location in the chromatographic system to produce a selected mass flow rate of the fluid.

Provided are apparatus and systems for performing a swing adsorption process. This swing adsorption process may involve passing an input feed stream through two swing adsorption systems as a purge stream to remove contaminants, such as water, from the respective adsorbent bed units. The wet purge product stream is passed to a solvent based gas treating system, which forms a wet hydrocarbon rich stream and a wet acid gas stream. Then, the wet hydrocarbon rich stream and the wet acid gas stream are passed through one of the respective swing adsorption systems to remove some of the moisture from the respective wet streams.

The disclosure relates to a system (10) for recovering lithium from lithium-containing fluids. It is provided that the system (10) comprises a first container (12) which contains a first sorbent (14) which is designed to bind lithium ions by adsorption, that the system (10) comprises a second container (16) which contains a second sorbent (18) which is designed to bind lithium ions by exchanging hydrogen ions for lithium ions, and that a fluid outlet of the first container (12) is fluidically connected to a fluid inlet of the second container (16).

A liquid pump is described, including two pumplet subassemblies, each including an actuator and a pump head, and a controller adapted to provide smooth flow at a command rate. Each pumplet subassembly sequentially, cyclically, and repetitively operates (i) in a first operational active dispensing stage and (ii) in a refilling and transitional repressurization in a second operational non-dispensing standby stage. The controller switches the active dispensing operation from the active pumplet subassembly to the alternate and non-dispensing pumplet subassembly in which refilled liquid has been pressurized in the transitional repressurization operation in the alternate and non-dispensing pumplet subassembly to match active dispensing pressure of the active pumplet subassembly.

A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible falling components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.

A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible failing components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.

The present disclosure relates to methods for the chromatographic separation of two or more sample components using a column while applying a time-pulsed pressure differential to the column and to apparatus for use in the same.